Journal ArticleDOI
Epidemiology of suicide in bipolar disorders: a systematic review of the literature.
Maurizio Pompili,Xenia Gonda,Gianluca Serafini,Marco Innamorati,Leo Sher,Mario Amore,Zoltan Rihmer,Paolo Girardi +7 more
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TLDR
The aim of the present paper is to provide a systematic review of the existing literature on the epidemiology of completed suicides in adult patients with bipolar disorder (BD).Abstract:
OBJECTIVE: Suicidal behavior is a major public health problem worldwide, and its prediction and prevention represent a challenge for everyone, including clinicians. The aim of the present paper is to provide a systematic review of the existing literature on the epidemiology of completed suicides in adult patients with bipolar disorder (BD). METHODS: We performed a Pubmed/Medline, Scopus, PsycLit, PsycInfo, and Cochrane database search to identify all relevant papers published between 1980 and 2011. A total of 34 articles meeting our inclusion criteria were included in the present review. RESULTS: Several prospective follow-up contributions, many retrospective analyses, and a few psychological autopsy studies and review articles investigated the epidemiology of completed suicides in patients with BD. The main finding of the present review was that the risk for suicide among BD patients was up to 20-30 times greater than that for the general population. CONCLUSION: Special attention should be given to the characteristics of suicides in patients with BD. Better insight and understanding of suicide and suicidal risk in this very disabling illness should ultimately help clinicians to adequately detect, and thus prevent, suicidal acts in patients with BD. Language: enread more
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Journal ArticleDOI
Structural-functional decoupling predicts suicide attempts in bipolar disorder patients with a current major depressive episode.
Haiteng Jiang,Rongxin Zhu,Shui Tian,Huan Wang,Zhilu Chen,Xinyi Wang,Junneng Shao,Jiaolong Qin,Jiabo Shi,Haiyan Liu,Yu Chen,Zhijian Yao,Zhijian Yao,Qing Lu +13 more
TL;DR: It is hypothesized that structure connectivity constrains functional connectivity, and structural–functional coupling is a more sensitive biomarker to detect subtle brain abnormalities than any single modality in BD patients with a current major depressive episode who had attempted suicide.
Journal ArticleDOI
The clinical characterization of the adult patient with bipolar disorder aimed at personalization of management
Roger S. McIntyre,Martin Alda,Ross J. Baldessarini,Michael Bauer,Michael Berk,Christoph U. Correll,Andrea Fagiolini,Kostas N. Fountoulakis,Mark A. Frye,Heinz Grunze,Lars Vedel Kessing,David J. Miklowitz,Gordon Parker,Robert M. Post,Alan C. Swann,Trisha Suppes,Eduard Vieta,Allan H. Young,Mario Maj +18 more
TL;DR: In this paper , the authors synthesize salient domains in the clinical characterization of the adult patient with bipolar disorder, with the overarching aim of improving health outcomes by informing patient management and treatment considerations.
Journal ArticleDOI
Tobacco smoking and other substance use disorders associated with recurrent suicide attempts in bipolar disorder
Romain Icick,Ingrid Melle,Bruno Etain,Petter Andreas Ringen,Sofie R. Aminoff,Marion Leboyer,Monica Aas,C. Henry,Thomas Bjella,Ole A. Andreassen,Frank Bellivier,Trine Vik Lagerberg +11 more
TL;DR: Regression analysis showed that tobacco smoking with- or without additional SUD can be important risk factors of SA recurrence in BD, which is likely to inform both research and prevention strategies.
Journal ArticleDOI
Serum oxytocin concentrations in current and recent suicide survivors are lower than in healthy controls
Leila Jahangard,Mehran Shayganfard,Farahnaz Ghiasi,Iraj Salehi,Mohammad Haghighi,Mohammad Ahmadpanah,Dena Sadeghi Bahmani,Serge Brand +7 more
TL;DR: The results support the notion that suicide attempts are closely linked to suicide survivors' perceptions of the quality of their social lives, and serum oxytocin concentrations support this notion.
Journal ArticleDOI
Relative toxicity of mood stabilisers and antipsychotics: case fatality and fatal toxicity associated with self-poisoning
Anne E. Ferrey,Galit Geulayov,Deborah Casey,Claudia Wells,Alice Fuller,Clare Bankhead,Jennifer Ness,Caroline Clements,David Gunnell,Navneet Kapur,Keith Hawton +10 more
TL;DR: Estimating the relative toxicity of specific drugs within two drug categories, antipsychotics and mood stabilizers, using large-scale databases to provide evidence that could assist clinicians in making decisions about prescribing, especially for patients at risk of suicidal behaviour is relevant to prescribing policy.
References
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Manic-Depressive Illness
TL;DR: In this paper, psychodynamic features of families with multigenerational bipolar manic-depressive illness are described, including avoidance of affect, unrealistic standards of conformity, absence of intimate relationships apart from family, displaced parental low self-esteem, and fears related to illness heritability.
Journal ArticleDOI
Suicide as an outcome for mental disorders. A meta-analysis.
E C Harris,B Barraclough +1 more
TL;DR: Almost all mental disorders have an increased risk of suicide excepting mental retardation and dementia, which is highest for functional and lowest for organic disorders with substance misuse disorders lying between.