Estimating F-statistics for the analysis of population structure.
Bruce S. Weir,C. Clark Cockerham +1 more
Reads0
Chats0
TLDR
The purpose of this discussion is to offer some unity to various estimation formulae and to point out that correlations of genes in structured populations, with which F-statistics are concerned, are expressed very conveniently with a set of parameters treated by Cockerham (1 969, 1973).Abstract:
This journal frequently contains papers that report values of F-statistics estimated from genetic data collected from several populations. These parameters, FST, FIT, and FIS, were introduced by Wright (1951), and offer a convenient means of summarizing population structure. While there is some disagreement about the interpretation of the quantities, there is considerably more disagreement on the method of evaluating them. Different authors make different assumptions about sample sizes or numbers of populations and handle the difficulties of multiple alleles and unequal sample sizes in different ways. Wright himself, for example, did not consider the effects of finite sample size. The purpose of this discussion is to offer some unity to various estimation formulae and to point out that correlations of genes in structured populations, with which F-statistics are concerned, are expressed very conveniently with a set of parameters treated by Cockerham (1 969, 1973). We start with the parameters and construct appropriate estimators for them, rather than beginning the discussion with various data functions. The extension of Cockerham's work to multiple alleles and loci will be made explicit, and the use of jackknife procedures for estimating variances will be advocated. All of this may be regarded as an extension of a recent treatment of estimating the coancestry coefficient to serve as a mea-read more
Citations
More filters
Journal ArticleDOI
Genetic diversity and introgression in the Scottish wildcat.
Mark A. Beaumont,E. M. Barratt,Dada Gottelli,Andrew C. Kitchener,M. J. Daniels,Jonathan K. Pritchard,Michael William Bruford +6 more
TL;DR: It is argued that this is evidence that these cats do not have very recent domestic ancestry, but from the morphological data it is highly likely that this gene pool also contains a contribution from earlier introgression of domestic cat genes.
Journal ArticleDOI
Genomic Diversity and Admixture Differs for Stone-Age Scandinavian Foragers and Farmers
Pontus Skoglund,Helena Malmström,Ayça Omrak,Maanasa Raghavan,Cristina Valdiosera,Torsten Günther,Per Hall,Kristiina Tambets,Jueri Parik,Karl-Göran Sjögren,Jan Apel,Eske Willerslev,Jan Storå,Anders Götherström,Mattias Jakobsson,Mattias Jakobsson +15 more
TL;DR: In this article, population-genomic data from 11 Scandinavian Stone Age human remains suggest that hunter-gatherers had lower genetic diversity than that of farmers, despite their close geographical proximity, the genetic differentiation between the two Stone Age groups was greater than that observed among extant European populations.
Journal ArticleDOI
Historical contingency and ecological determinism interact to prime speciation in sticklebacks, Gasterosteus.
Eric B. Taylor,J. Donald McPhail +1 more
TL;DR: Sympatric sticklebacks provide an example of adaptive radiation by determinism contingent upon historical conditions promoting unique ecological interactions, and illustrate how contingency and determinism may interact to generate geographical variation in species diversity.
Journal ArticleDOI
Sex-biased dispersal of great white sharks
Amanda T. Pardini,Catherine S. Jones,Leslie R. Noble,Brian R. Kreiser,Brian R. Kreiser,Hamish A. Malcolm,Barry D. Bruce,John D. Stevens,Geremy Cliff,Michael C. Scholl,Malcolm P. Francis,Clinton A. J. Duffy,Andrew P. Martin +12 more
TL;DR: In some respects, these sharks behave more like whales and dolphins than other fish.
Journal ArticleDOI
Recent habitat fragmentation caused by major roads leads to reduction of gene flow and loss of genetic variability in ground beetles
Irene Keller,Carlo R. Largiadèr +1 more
TL;DR: Findings strongly support the hypothesis that large roads are absolute barriers to gene flow in C. violaceus, which may lead to a loss of genetic variability in fragmented populations.
References
More filters
Journal ArticleDOI
Analysis of Gene Diversity in Subdivided Populations
TL;DR: A method is presented by which the gene diversity (heterozygosity) of a subdivided population can be analyzed into its components, i.e., the gene diversities within and between subpopulations.
Book
The jackknife, the bootstrap, and other resampling plans
TL;DR: The Delta Method and the Influence Function Cross-Validation, Jackknife and Bootstrap Balanced Repeated Replication (half-sampling) Random Subsampling Nonparametric Confidence Intervals as mentioned in this paper.
Journal ArticleDOI
The interpretation of population structure by F-statistics with special regard to systems of mating
TL;DR: It was found that there is no equilibrium in either case short of complete fixation locally, in spite of the linear increase in number of different ancestors with increasing number of ancestral generations, in contrast to systems (half first cousin or second cousin) in which this increase is more than linear and a steady state is rapidly attained with respect to heterozygosis.
Related Papers (5)
Inference of population structure using multilocus genotype data
GENEPOP (Version 1.2): Population Genetics Software for Exact Tests and Ecumenicism
Michel Raymond,François Rousset +1 more