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Ethanol and supercritical fluid extracts of hemp seed (Cannabis sativa L.) increase gene expression of antioxidant enzymes in HepG2 cells

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TLDR
The gene expression of antioxidant enzymes by hemp seed extracts in human hepatoma (HepG2) cells is determined by studying the activity of these enzymes in response to the presence or absence of polypeptide A in hepatoma cells.
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This article is published in Asian Pacific Journal of Reproduction.The article was published on 2015-06-01 and is currently open access. It has received 25 citations till now. The article focuses on the topics: Superoxide dismutase.

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Hempseed in food industry: Nutritional value, health benefits, and industrial applications

TL;DR: The chemical composition, nutritional value, and potential health benefits of hempseed, as researched via in vitro and in vivo trials were compared and the latest processing methods developed to improve these properties were compared.
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Cannabinoids in cancer treatment: Therapeutic potential and legislation

TL;DR: Understanding how cannabinoids are able to regulate essential cellular processes involved in tumorigenesis, such as progression through the cell cycle, cell proliferation and cell death, as well as the interactions between cannabinoids and the immune system, are crucial for improving existing and developing new therapeutic approaches for cancer patients.
Journal ArticleDOI

Supercritical carbon dioxide extraction of cannabinoids from Cannabis sativa L.

TL;DR: In this article, the effect of ethanol as co-solvent was investigated for supercritical carbon dioxide (CO 2 ) extraction of four different Cannabis sativa L. strains with variable cannabinoids initial content.
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Chemical composition and nutraceutical properties of hempseed: an ancient food with actual functional value

TL;DR: In this article, the authors provide a detailed and updated background for research on seeds of this niche crop, pointing out the chemistry and bioactivity of their phytochemicals, and highlight it is an inestimable source of health promoting ingredients.
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Hemp (Cannabis Sativa L.) Extract: Anti-Microbial Properties, Methods of Extraction, and Potential Oral Delivery

TL;DR: Novel advances in technologies designed to use nano-carriers for oral delivery of cannabinoids are introduced with the goal to highlight the latest developments in hemp extract processing and delivery.
References
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Journal ArticleDOI

A new mathematical model for relative quantification in real-time RT-PCR.

TL;DR: This study enters into the particular topics of the relative quantification in real-time RT-PCR of a target gene transcript in comparison to a reference gene transcript and presents a new mathematical model that needs no calibration curve.
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Antioxidant activity applying an improved ABTS radical cation decolorization assay.

TL;DR: A method for the screening of antioxidant activity is reported as a decolorization assay applicable to both lipophilic and hydrophilic antioxidants, including flavonoids, hydroxycinnamates, carotenoids, and plasma antioxidants.
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Free radicals and antioxidants in normal physiological functions and human disease

TL;DR: Attention is focussed on the ROS/RNS-linked pathogenesis of cancer, cardiovascular disease, atherosclerosis, hypertension, ischemia/reperfusion injury, diabetes mellitus, neurodegenerative diseases, rheumatoid arthritis, and ageing.
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Free radicals, metals and antioxidants in oxidative stress-induced cancer

TL;DR: This review examines the evidence for involvement of the oxidative stress in the carcinogenesis process and the role of enzymatic and non-enzymatic antioxidants in the process of carcinogenesis as well as the antioxidant interactions with various regulatory factors.
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Chemical constituents of marijuana: The complex mixture of natural cannabinoids

TL;DR: The chemical constituents of the plant are discussed with particular emphasis on the cannabinoids as the class of compounds responsible for the drug's psychological properties.
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