scispace - formally typeset
Open AccessJournal ArticleDOI

Fabrication and Characterization of Magnetic Microrobots for Three-Dimensional Cell Culture and Targeted Transportation

Reads0
Chats0
TLDR
Three-dimensional porous structures fabricated with an SU-8 photoresist using a 3D laser lithography system for targeted cell transportation and human embryonic kidney 239 cells are cultivated in the microrobot.
Abstract
Magnetically manipulated microrobots are demonstrated for targeted cell transportation. Full three-dimensional (3D) porous structures are fabricated with an SU-8 photoresist using a 3D laser lithography system. Nickel and titanium are deposited as a magnetic material and biocompatible material, respectively. The fabricated microrobots are controlled in the fluid by external magnetic fields. Human embryonic kidney 239 (HEK 239) cells are cultivated in the microrobot to show the possibility for targeted cell transportation.

read more

Citations
More filters
Proceedings ArticleDOI

A New Method for Creating a Wound Model with Micro-robot in Microfluidic Device

TL;DR: In this article, the authors describe a comparative two-dimensional and three-dimensional wound healing assay with wound generated via exclusively designed and magnetically manipulated micro-robot and the healing process is observed with a holographic imaging setup.
Journal ArticleDOI

Advanced medical micro-robotics for early diagnosis and therapeutic interventions

TL;DR: In this paper , the major challenges, current trends and significant achievements for developing versatile and intelligent micro-robotics with a focus on applications in early diagnosis and therapeutic interventions are reviewed.
Journal ArticleDOI

Magnet‐Driven Microwalker in Surface Motion Based on Frictional Anisotropy

TL;DR: In this article , a magnetically powered and frictional anisotropy-based microwalker that can be potentially used in in vivo non-liquid-filled environment is proposed.
Proceedings ArticleDOI

Magnetically-guided in-situ microrobot fabrication

TL;DR: A new, 3D printing inspired method for in-situ fabrication of mobile magnetic microrobots with complex topology from a polymer filament on demand directly inside an enclosed operational environment, with the potential for scaled down applications in healthcare and microfluidics.
Proceedings ArticleDOI

Development of Magnetically Driven Microrobots for Targeted Cell Delivery, and Their Characterization in in Vitro, Ex Vivo and in Vivo Environments

TL;DR: The proposed magnetically driven microrobots demonstrated stem cell transportation inside the body cavity of the nude mouse as a proof of concept of targeted cell delivery and shown the feasibility of future applications in precision medicine.
References
More filters
Journal ArticleDOI

Life at low Reynolds number

TL;DR: Weisskopf as mentioned in this paper presented a transparencies of a tall rectangular transparent vessel of corn syrup, projected by an overhead projector turned on its side, which was itself a slightly edited transcript of a tape.
Journal ArticleDOI

Microrobots for Minimally Invasive Medicine

TL;DR: The aim of this review is to provide a comprehensive survey of the technological state of the art in medical microrobots, to explore the potential impact of medical micRORobots and inspire future research in this field.
Journal ArticleDOI

Artificial bacterial flagella: Fabrication and magnetic control

TL;DR: ABF swimmers represent the first demonstration of microscopic artificial swimmers that use helical propulsion and are of interest in fundamental research and for biomedical applications.
Journal ArticleDOI

Magnetic Helical Micromachines: Fabrication, Controlled Swimming, and Cargo Transport

TL;DR: A simple and general fabrication method for helical swimming micromachines by direct laser writing and e-beam evaporation is demonstrated and the magnetic helical devices exhibit varying magnetic shape anisotropy, yet always generate corkscrew motion using a rotating magnetic field.

Adhesion of cells to surfaces coated with polylysine

TL;DR: The attachment of cells to the polylysine-treated surfaces can be exploited for a variety of experimental manipulations and is found to be the case for nuclei isolated from sea urchin embryos and for the microtubules of flagella, which are well displayed after the membrane has been disrupted by Triton X-100.
Related Papers (5)