Fabrication and Characterization of Magnetic Microrobots for Three-Dimensional Cell Culture and Targeted Transportation
Sangwon Kim,Famin Qiu,Samhwan Kim,Ali Ghanbari,Cheil Moon,Li Zhang,Bradley J. Nelson,Bradley J. Nelson,Hongsoo Choi +8 more
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TLDR
Three-dimensional porous structures fabricated with an SU-8 photoresist using a 3D laser lithography system for targeted cell transportation and human embryonic kidney 239 cells are cultivated in the microrobot.Abstract:
Magnetically manipulated microrobots are demonstrated for targeted cell transportation. Full three-dimensional (3D) porous structures are fabricated with an SU-8 photoresist using a 3D laser lithography system. Nickel and titanium are deposited as a magnetic material and biocompatible material, respectively. The fabricated microrobots are controlled in the fluid by external magnetic fields. Human embryonic kidney 239 (HEK 239) cells are cultivated in the microrobot to show the possibility for targeted cell transportation.read more
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Biomedical Applications of Untethered Mobile Milli/Microrobots
Metin Sitti,Metin Sitti,Hakan Ceylan,Wenqi Hu,Joshua Giltinan,Mehmet Turan,Sehyuk Yim,Eric Diller +7 more
TL;DR: A comprehensive review of the current advances in biomedical untethered mobile milli/microrobots and discusses the existing challenges and emerging concepts associated with designing such a miniaturized robot for operation inside a biological environment for biomedical applications.
Journal ArticleDOI
Controlled In Vivo Swimming of a Swarm of Bacteria‐Like Microrobotic Flagella
Ania Servant,Ania Servant,Famin Qiu,Mariarosa Mazza,Mariarosa Mazza,Kostas Kostarelos,Kostas Kostarelos,Bradley J. Nelson +7 more
TL;DR: In vivo imaging and actuation of a swarm of magnetic helical microswimmers by external magnetic fields in deep tissue is demonstrated for the first time, yielding a generation of micrometer-scale transporters with numerous applications in biomedicine including synthetic biology, assisted fertilization, and drug/gene delivery.
Journal ArticleDOI
Millimeter-scale flexible robots with programmable three-dimensional magnetization and motions
TL;DR: A method for patterning hard magnetic microparticles in an elastomer matrix based on ultraviolet (UV) lithography, which uses controlled reorientation of magnetic particles and selective exposure to UV light to encode magnetic particles in planar materials with arbitrary 3D orientation with a geometrical feature size as small as 100 micrometers.
Journal ArticleDOI
Fuel-Free Synthetic Micro-/Nanomachines.
TL;DR: Recent developments on fuel-free micro-/nanomotors (powered by various external stimuli such as light, magnetic, electric, or ultrasonic fields) are summarized, ranging from fabrication to propulsion mechanisms.
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Two-Component Polymer Scaffolds for Controlled Three-Dimensional Cell Culture
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Artificial bacterial flagella for micromanipulation
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