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Open AccessJournal ArticleDOI

Fabrication and Characterization of Magnetic Microrobots for Three-Dimensional Cell Culture and Targeted Transportation

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TLDR
Three-dimensional porous structures fabricated with an SU-8 photoresist using a 3D laser lithography system for targeted cell transportation and human embryonic kidney 239 cells are cultivated in the microrobot.
Abstract
Magnetically manipulated microrobots are demonstrated for targeted cell transportation. Full three-dimensional (3D) porous structures are fabricated with an SU-8 photoresist using a 3D laser lithography system. Nickel and titanium are deposited as a magnetic material and biocompatible material, respectively. The fabricated microrobots are controlled in the fluid by external magnetic fields. Human embryonic kidney 239 (HEK 239) cells are cultivated in the microrobot to show the possibility for targeted cell transportation.

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Citations
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Journal ArticleDOI

Biocompatible polymers with tunable mechanical properties and conductive functionality on two-photon 3D printing

TL;DR: Li et al. as mentioned in this paper proposed a printable polymer formula with good mechanical tunability, high resolution, strong functional scalability, and excellent biocompatibility, by using the synergistic effects of a hydroxyl group-containing photocurable resin prepolymer, UV acrylate monomer, long-chain hydrophilic crosslinking monomer and photo-initiator.
Proceedings ArticleDOI

Fabrication and targeted particle delivery using microrobots

TL;DR: This work demonstrated loading, encapsulation, and unloading of micro-bead with the fabricated microrobot with rotating magnetic field, showing the potential for drug delivery and cell transportation without coating or fixing the drug and cells on the micRORobot surface.
Book ChapterDOI

Nonlinear Modeling Application to Micro-/Nanorobotics

TL;DR: Application of microrobots can move us to the stage that monitoring diseases, precise localized drug delivery, minimally invasive surgery, and novel therapies such as stem cell therapy are done using the tools inside the human body.
Journal ArticleDOI

Physically Soft Magnetic Films and Devices: Fabrication, Properties, Printability, and Applications

TL;DR: In this paper , the authors developed materials that enable fabricating multifunctional devices, which makes these devices capable of novel applications ranging from energy, storage, and communication, among others.
Proceedings ArticleDOI

Direct laser writing of 3D protein structures with nanoscale feature sizes

TL;DR: In this article, the authors reported the fabrication of 2D and 3D protein structures with nm-sized features using two-photon direct laser writing (DLW) and showed the biocompatibility of protein structures to 3T3 fibroblasts.
References
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Journal ArticleDOI

Life at low Reynolds number

TL;DR: Weisskopf as mentioned in this paper presented a transparencies of a tall rectangular transparent vessel of corn syrup, projected by an overhead projector turned on its side, which was itself a slightly edited transcript of a tape.
Journal ArticleDOI

Microrobots for Minimally Invasive Medicine

TL;DR: The aim of this review is to provide a comprehensive survey of the technological state of the art in medical microrobots, to explore the potential impact of medical micRORobots and inspire future research in this field.
Journal ArticleDOI

Artificial bacterial flagella: Fabrication and magnetic control

TL;DR: ABF swimmers represent the first demonstration of microscopic artificial swimmers that use helical propulsion and are of interest in fundamental research and for biomedical applications.
Journal ArticleDOI

Magnetic Helical Micromachines: Fabrication, Controlled Swimming, and Cargo Transport

TL;DR: A simple and general fabrication method for helical swimming micromachines by direct laser writing and e-beam evaporation is demonstrated and the magnetic helical devices exhibit varying magnetic shape anisotropy, yet always generate corkscrew motion using a rotating magnetic field.

Adhesion of cells to surfaces coated with polylysine

TL;DR: The attachment of cells to the polylysine-treated surfaces can be exploited for a variety of experimental manipulations and is found to be the case for nuclei isolated from sea urchin embryos and for the microtubules of flagella, which are well displayed after the membrane has been disrupted by Triton X-100.
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