Fabrication and Characterization of Magnetic Microrobots for Three-Dimensional Cell Culture and Targeted Transportation
Sangwon Kim,Famin Qiu,Samhwan Kim,Ali Ghanbari,Cheil Moon,Li Zhang,Bradley J. Nelson,Bradley J. Nelson,Hongsoo Choi +8 more
Reads0
Chats0
TLDR
Three-dimensional porous structures fabricated with an SU-8 photoresist using a 3D laser lithography system for targeted cell transportation and human embryonic kidney 239 cells are cultivated in the microrobot.Abstract:
Magnetically manipulated microrobots are demonstrated for targeted cell transportation. Full three-dimensional (3D) porous structures are fabricated with an SU-8 photoresist using a 3D laser lithography system. Nickel and titanium are deposited as a magnetic material and biocompatible material, respectively. The fabricated microrobots are controlled in the fluid by external magnetic fields. Human embryonic kidney 239 (HEK 239) cells are cultivated in the microrobot to show the possibility for targeted cell transportation.read more
Citations
More filters
Journal ArticleDOI
Light‐Fueled Microscopic Walkers
Hao Zeng,Piotr Wasylczyk,Camilla Parmeggiani,Daniele Martella,Matteo Burresi,Diederik S. Wiersma +5 more
TL;DR: The first microscopic artificial walker equipped with liquid-crystalline elastomer muscle is reported, which is smaller than any known living terrestrial creatures, and is capable of several autonomous locomotions on different surfaces.
Journal ArticleDOI
Magnetic Helical Microswimmers Functionalized with Lipoplexes for Targeted Gene Delivery
Famin Qiu,Satoshi Fujita,Satoshi Fujita,Rami Mhanna,Li Zhang,Benjamin R. Simona,Bradley J. Nelson +6 more
TL;DR: The successful wirelessly targeted and single‐cell gene delivery to human embryonic kidney cells using ABFs loaded with plasmid DNA (pDNA) in vitro is demonstrated for the first time.
Journal ArticleDOI
Recent developments in magnetically driven micro- and nanorobots
Xiang-Zhong Chen,Marcus Hoop,Fajer Mushtaq,Erdem C. Siringil,Chengzhi Hu,Bradley J. Nelson,Salvador Pané +6 more
TL;DR: A short review of magnetically driven micro-and nanorobots developed in our laboratory and by other research groups is presented in this paper, where different designs such as helical swimmers, flexible swimmers and surface walkers are categorized and discussed.
Journal ArticleDOI
Development of a magnetic microrobot for carrying and delivering targeted cells
Junyang Li,Xiaojian Li,Tao Luo,Ran Wang,C.T. Liu,Shuxun Chen,Dongfang Li,Jianbo Yue,Shuk Han Cheng,Dong Sun +9 more
TL;DR: A microrobotic device platform for regenerative medicine and cell-based therapy with a burr-like porous spherical structure for carrying and delivering targeted cells in vivo under a magnetic gradient field–driven mechanism is presented.
Journal ArticleDOI
Magnetically Driven Micro and Nanorobots
TL;DR: MagRobots as discussed by the authors introduce fundamental concepts and advantages of magnetic micro/nanorobots as well as basic knowledge of magnetic fields and magnetic materials, setups for magnetic manipulation, magnetic field configurations, and symmetry-breaking strategies for effective movement.
References
More filters
Journal ArticleDOI
Life at low Reynolds number
TL;DR: Weisskopf as mentioned in this paper presented a transparencies of a tall rectangular transparent vessel of corn syrup, projected by an overhead projector turned on its side, which was itself a slightly edited transcript of a tape.
Journal ArticleDOI
Microrobots for Minimally Invasive Medicine
TL;DR: The aim of this review is to provide a comprehensive survey of the technological state of the art in medical microrobots, to explore the potential impact of medical micRORobots and inspire future research in this field.
Journal ArticleDOI
Artificial bacterial flagella: Fabrication and magnetic control
TL;DR: ABF swimmers represent the first demonstration of microscopic artificial swimmers that use helical propulsion and are of interest in fundamental research and for biomedical applications.
Journal ArticleDOI
Magnetic Helical Micromachines: Fabrication, Controlled Swimming, and Cargo Transport
Soichiro Tottori,Li Zhang,Famin Qiu,Krzysztof Krawczyk,Alfredo Franco-Obregón,Bradley J. Nelson +5 more
TL;DR: A simple and general fabrication method for helical swimming micromachines by direct laser writing and e-beam evaporation is demonstrated and the magnetic helical devices exhibit varying magnetic shape anisotropy, yet always generate corkscrew motion using a rotating magnetic field.
Adhesion of cells to surfaces coated with polylysine
Daniel Mazia,Gerald Schatten +1 more
TL;DR: The attachment of cells to the polylysine-treated surfaces can be exploited for a variety of experimental manipulations and is found to be the case for nuclei isolated from sea urchin embryos and for the microtubules of flagella, which are well displayed after the membrane has been disrupted by Triton X-100.