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Open AccessJournal ArticleDOI

Fabrication and Characterization of Magnetic Microrobots for Three-Dimensional Cell Culture and Targeted Transportation

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TLDR
Three-dimensional porous structures fabricated with an SU-8 photoresist using a 3D laser lithography system for targeted cell transportation and human embryonic kidney 239 cells are cultivated in the microrobot.
Abstract
Magnetically manipulated microrobots are demonstrated for targeted cell transportation. Full three-dimensional (3D) porous structures are fabricated with an SU-8 photoresist using a 3D laser lithography system. Nickel and titanium are deposited as a magnetic material and biocompatible material, respectively. The fabricated microrobots are controlled in the fluid by external magnetic fields. Human embryonic kidney 239 (HEK 239) cells are cultivated in the microrobot to show the possibility for targeted cell transportation.

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Book ChapterDOI

Magnetic Field-Based Technologies for Lab-on-a-Chip Applications

TL;DR: In this chapter, magnetic field-based technologies, their basic theory, and main applications in LOC scenario will be discussed, by foreseeing also a deeper interaction/integration with the typical technologies of microrobotics.
Journal ArticleDOI

Engineered Magnetic Nanocomposites to Modulate Cellular Function.

TL;DR: Magnetic nanoparticles (MNPs) have various applications in biomedicine, including imaging, drug delivery and release, genetic modification, cell guidance, and patterning.
Proceedings ArticleDOI

Mobile paramagnetic nanoparticle-based vortex for targeted cargo delivery in fluid

TL;DR: A novel method of using millions of magnetic nanoparticles to generate a dynamic-equilibrium particle-based vortex, which can manipulate multiple cargos simultaneously at the microscale, and allows to perform micromanipulation using the collective behaviour of nanoparticles and to develop new strategies for the formation and control of the microrobotic swarm.
DissertationDOI

Solution synthesis and actuation of magnetic nanostructures

Peter Vach
TL;DR: In this article, a method to synthesize magnetic nanostructures in solution which can be actuated by external rotating magnetic fields is presented, which is scalable and can cheaply produce randomly shaped magnetic structures in large quantities.
Proceedings ArticleDOI

Methods and Results for Rotation of Diamagnetic Robots Using Translational Designs

TL;DR: In this article, the authors explore the use of novel control strategies and mechanical constraints to provide additional rotational degrees of freedom to underactuated multipole magnetic robots originally designed with only translational degree of freedom.
References
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Life at low Reynolds number

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Journal ArticleDOI

Microrobots for Minimally Invasive Medicine

TL;DR: The aim of this review is to provide a comprehensive survey of the technological state of the art in medical microrobots, to explore the potential impact of medical micRORobots and inspire future research in this field.
Journal ArticleDOI

Artificial bacterial flagella: Fabrication and magnetic control

TL;DR: ABF swimmers represent the first demonstration of microscopic artificial swimmers that use helical propulsion and are of interest in fundamental research and for biomedical applications.
Journal ArticleDOI

Magnetic Helical Micromachines: Fabrication, Controlled Swimming, and Cargo Transport

TL;DR: A simple and general fabrication method for helical swimming micromachines by direct laser writing and e-beam evaporation is demonstrated and the magnetic helical devices exhibit varying magnetic shape anisotropy, yet always generate corkscrew motion using a rotating magnetic field.

Adhesion of cells to surfaces coated with polylysine

TL;DR: The attachment of cells to the polylysine-treated surfaces can be exploited for a variety of experimental manipulations and is found to be the case for nuclei isolated from sea urchin embryos and for the microtubules of flagella, which are well displayed after the membrane has been disrupted by Triton X-100.
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