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Free radicals, lipid peroxidation, and cell damage.
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This article is published in The Lancet.The article was published on 1984-11-10. It has received 131 citations till now. The article focuses on the topics: Lipid peroxidation & Free-radical theory of aging.read more
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Yeast Stress Responses
Stefan Hohmann,Willem H. Mager +1 more
TL;DR: The environmental stress response: a common yeast response to diverse environmental stresses.
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Alpha-ketoglutarate dehydrogenase: a target and generator of oxidative stress
Laszlo Tretter,Vera Adam-Vizi +1 more
TL;DR: The pathological relevance of these two features of α-KGDH is discussed in this review, particularly in relation to neurodegeneration, as an impaired function of this enzyme has been found to be characteristic for several Neurodegenerative diseases.
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Reactive oxygen species and yeast apoptosis.
TL;DR: The nature of the ROS involved, the damage they cause to cells, the responses of S. cerevisiae to ROS are summarised, and those aspects in which ROS affect cell integrity that may be relevant to the apoptotic process are discussed.
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Antioxidants: Molecules, Medicines, and Myths
TL;DR: This article re-examines and challenges some basic assumptions in the nutritional antioxidant field and suggests that pro-oxidants can be better for you in some circumstances.
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Global analysis of the Bacillus subtilis Fur regulon and the iron starvation stimulon.
TL;DR: Twenty operons (containing 39 genes) are identified that are derepressed both by mutation of fur and by treatment of cells with the iron chelator 2,2′‐dipyridyl, and these operons are direct targets of Fur regulation as judged by DNase I footprinting.
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Free radical mechanisms in tissue injury
TL;DR: This short review of free radicals discusses certain types of free radical, such as nitroxyl-radicals and free radicals stabilized by steric or derealization features, which are stable enough to be crystallised and stored at temperatures above 0°.
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Lipid peroxidation, oxygen radicals, cell damage, and antioxidant therapy.
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FUNCTIONAL and STRUCTURAL ASPECTS OF BIOLOGICAL MEMBRANES: A SUGGESTED STRUCTURAL ROLE FOR VITAMIN E IN THE CONTROL OF MEMBRANE PERMEABILITY and STABILITY
TL;DR: It is proposed that uncontrolled changes in membrane permeability and stability may occur in the absence of vitamin E, and hence that a deficiency of this vitamin may lead to a failure of compartmentalization by biological membranes.
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An approach to free radicals
TL;DR: Free radicals have become a buzz word in experimental pathology and they are beginning to impinge on clinical practice.