Fructose transporter in human spermatozoa and small intestine is GLUT5.
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TLDR
The biochemical properties and tissue distribution of GLUT5 are consistent with a physiological role for this protein as a fructose transporter.About:
This article is published in Journal of Biological Chemistry.The article was published on 1992-07-25 and is currently open access. It has received 508 citations till now. The article focuses on the topics: Fructose transport & GLUT5.read more
Citations
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Facilitative glucose transporters
TL;DR: This review summarizes recent advances concerning the structure, function, and regulation of the Glut proteins.
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Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer
TL;DR: Targeting GLUT12 could provide novel methods for detection and treatment of breast and prostate cancer and help clarify the role of glucose transporter expression in breast cancer.
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Exercise, glucose transport, and insulin sensitivity.
TL;DR: There is now extensive epidemiological evidence demonstrating that long-term regular physical exercise can significantly reduce the risk of developing non-insulin-dependent diabetes mellitus.
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The SLC2 (GLUT) family of membrane transporters.
Mike Mueckler,Bernard Thorens +1 more
TL;DR: This review describes the major characteristics of the 14 GLUT family members and concludes that GLUTs 1-5 are the most thoroughly studied and all have well established roles as glucose and/or fructose transporters in various tissues and cell types.
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Phlorizin: a review.
TL;DR: The dihydrochalcone phlorizin is a natural product and dietary constituent found in a number of fruit trees that has been used as a pharmaceutical and tool for physiology research for over 150 years.
References
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Human facilitative glucose transporters. Isolation, functional characterization, and gene localization of cDNAs encoding an isoform (GLUT5) expressed in small intestine, kidney, muscle, and adipose tissue and an unusual glucose transporter pseudogene-like sequence (GLUT6).
Toshiaki Kayano,Charles F. Burant,Hirofumi Fukumoto,Gwyn W. Gould,Yao Shan Fan,Roger L. Eddy,Mary G. Byers,Thomas B. Shows,Susumu Seino,Graeme I. Bell +9 more
TL;DR: Two novel facilitative glucose transporter-like cDNAs have been isolated from human small intestine and fetal skeletal muscle cDNA libraries by low stringency cross-hybridization with a fragment of the human erythrocyte/GLUT1 facilitatives glucose transporter cDNA.
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Facilitated diffusion of glucose
TL;DR: Article de synthese sur the diffusion facilite du glucose a travers les membranes cellulaires a travers le membranes cellulaire.
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Expression of human glucose transporters in Xenopus oocytes: kinetic characterization and substrate specificities of the erythrocyte, liver, and brain isoforms.
TL;DR: It is shown that, for all transporters, the transport of 2-deoxy-D-glucose is inhibited by D-but not by L- glucose, and both D-galactose and D-mannose are transported by GLUTs 1-3 at significant rates; furthermore, GLUT 2 is capable of transporting D-fructose.
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Liver glucose transporter: a basolateral protein in hepatocytes and intestine and kidney cells
TL;DR: The "liver" isoform of the facilitated diffusion glucose transporter is expressed predominantly in liver, intestine, kidney, and pancreatic islet beta-cells, indicating that there are tissue-specific posttranslational modifications of the same transporter polypeptide.
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Localization of the pancreatic beta cell glucose transporter to specific plasma membrane domains.
TL;DR: Results support a possible role for this glucose transporter in glucose sensing by beta cells and provide evidence that these cells are polarized.
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Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney, and β-pancreatic islet cells
The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review).
Hans-Georg Joost,Bernard Thorens +1 more