Generation of Triplet Excited States via Photoinduced Electron Transfer in meso-anthra-BODIPY: Fluorogenic Response toward Singlet Oxygen in Solution and in Vitro
Mikhail A. Filatov,Safakath Karuthedath,Pavel M. Polestshuk,Huguette Savoie,Keith J. Flanagan,Cindy Sy,Elisabeth Sitte,Maxime Telitchko,Frédéric Laquai,Ross W. Boyle,Mathias O. Senge +10 more
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TLDR
1O2 generation by BADs in living cells enables visualization of the dyads distribution, promising new imaging applications.Abstract:
Heavy atom-free BODIPY-anthracene dyads (BADs) generate locally excited triplet states by way of photoinduced electron transfer (PeT), followed by recombination of the resulting charge-separated states (CSS). Subsequent quenching of the triplet states by molecular oxygen produces singlet oxygen (1O2), which reacts with the anthracene moiety yielding highly fluorescent species. The steric demand of the alkyl substituents in the BODIPY subunit defines the site of 1O2 addition. Novel bis- and tetraepoxides and bicyclic acetal products, arising from rearrangements of anthracene endoperoxides were isolated and characterized. 1O2 generation by BADs in living cells enables visualization of the dyads distribution, promising new imaging applications.read more
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Journal ArticleDOI
Color-Tunable Delayed Fluorescence and Efficient Spin–Orbit Charge Transfer Intersystem Crossing in Compact Carbazole-Anthracene-Bodipy Triads Employing the Sequential Electron Transfer Approach
Zafar Mahmood,Zafar Mahmood,Maria Taddei,Noreen Rehmat,Laura Bussotti,Sandra Doria,Qinglin Guan,Shaomin Ji,Jianzhang Zhao,Mariangela Di Donato,Yanping Huo,Yong Heng Xing +11 more
TL;DR: In this article, two triads composed of carbazole (CZ), anthracene (AN), and bodipy (BDP) moieties were devised to study the effect on photophysical properties, especially on SOCT-ISC efficiency.
Journal ArticleDOI
Efficient Intersystem Crossing in the Tröger's Base Derived From 4-Amino-1,8-naphthalimide and Application as a Potent Photodynamic Therapy Reagent.
Yingjie Zhao,Kepeng Chen,Elif Akhuseyin Yildiz,Shujing Li,Yuqi Hou,Xue Zhang,Zhijia Wang,Jianzhang Zhao,Antonio Barbon,Halime Gul Yaglioglu,Huijian Wu +10 more
TL;DR: Intersystem crossing (ISC) was observed for naphthalimide-derived Tröger's base, and the ISC is confirmed as spin orbital charge transfer ISC (SOCT-ISC) mechanism.
Journal ArticleDOI
Pyrazole appended quinoline-BODIPY based arene ruthenium complexes: their anticancer activity and potential applications in cellular imaging.
Rajendra Prasad Paitandi,Vinay Sharma,Vishwa Deepak Singh,Bhupendra Kumar Dwivedi,Shaikh M. Mobin,Daya Shankar Pandey +5 more
TL;DR: In vitro antiproliferative activity and photocytotoxicity of 1-4 were examined against the human cervical cancer cell line (HeLa) which clearly showed that these complexes behave as a potential theranostic agent and their ability to kill cancer cells under visible light lies in the order 4 > 3 > 2 > 1.
Journal ArticleDOI
Twisted BODIPY derivative: intersystem crossing, electron spin polarization and application as a novel photodynamic therapy reagent.
Yu Dong,Prashant Kumar,Partha Maity,Ivan V. Kurganskii,Shujing Li,Ayhan Elmali,Jianzhang Zhao,Daniel Escudero,Huijian Wu,Ahmet Karatay,Omar F. Mohammed,Matvey V. Fedin +11 more
TL;DR: In this paper, the photophysical properties of a heavy atom-free BODIPY derivative with a twisted π-conjugated framework were studied, and the results were consistent with TREPR results on the electron spin selectivity (the overpopulation of the TY sublevel of the T1 state).
Journal ArticleDOI
Supramolecular assembly confined purely organic room temperature phosphorescence and its biological imaging
TL;DR: In this article , a review mainly focuses on macrocyclic (cyclodextrin and cucurbituril) hosts, nanoassembly, and macromolecule (polyether) confinement-driven RTP.
References
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Journal ArticleDOI
BODIPY dyes in photodynamic therapy.
TL;DR: The attributes of BODIPY dyes for PDT are summarized, and substituents with appropriate oxidation potentials are summarized in some related areas.
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Reaction-based small-molecule fluorescent probes for chemoselective bioimaging
TL;DR: A survey of tools and tactics for using small-molecule fluorescent probes to detect biologically important chemical analytes is presented, highlighting design criteria for effective chemical tools for use in biological applications as well as gaps for future exploration.
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The triplet excited state of Bodipy: formation, modulation and application
TL;DR: The methods for switching (or modulation) of the triplet excited state of Bodipy were discussed, such as those based on the photo-induced electron transfer (PET), by controlling the competing Förster-resonance-energy-transfer (FRET), or the intermolecular charge transfer (ICT).
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Design and Synthesis of a Library of BODIPY-Based Environmental Polarity Sensors Utilizing Photoinduced Electron-Transfer-Controlled Fluorescence ON/OFF Switching
TL;DR: A library of probes in which the threshold of fluorescence ON/OFF switching corresponds to different levels of solvent polarity is designed and synthesized, which were used to examine bovine serum albumin and living cells and concluded to be similar to that of acetone.