Journal ArticleDOI
Genetic Markers of Sleep and Sleepiness.
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TLDR
The genetic underpinnings of chronotype and of sleep, including sleepiness, sleep quality and latency, and sleep timing and duration in healthy adult sleepers, are reviewed, drawing on candidate gene and genome-wide association studies.About:
This article is published in Sleep Medicine Clinics.The article was published on 2017-09-01. It has received 21 citations till now. The article focuses on the topics: Chronotype & Sleep in non-human animals.read more
Citations
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Journal ArticleDOI
Sleep Apnea and Sleep Habits: Relationships with Metabolic Syndrome.
TL;DR: The present review focuses on the role of sleep habits in the development of metabolic syndrome, on the reciprocal relationship between sleep apnea and metabolic Syndrome, and on the results of sleep intervention studies.
Journal ArticleDOI
Neurobehavioral Effects and Biomarkers of Sleep Loss in Healthy Adults
TL;DR: Sleep loss is increasingly prevalent and produces reliable, differential neurobehavioral deficits across individuals, and recent research has identified biomarkers to predict these responses, though future work is warranted, such that precise determination of who will develop neuro behavioral decrements from sleep loss will be possible.
Genome-wide association study of sleep duration in the Finnish population
Hanna Ollila,Hanna Ollila,Johannes Kettunen,Olli Pietiläinen,Olli Pietiläinen,Vilma Aho,Kaisa Silander,Erkki Kronholm,Markus Perola,Jari Lahti,Katri Räikkönen,Elisabeth Widen,Aarno Palotie,Johan G. Eriksson,Timo Partonen,Jaakko Kaprio,Jaakko Kaprio,Veikko Salomaa,Olli T. Raitakari,Terho Lehtimäki,Mikael Sallinen,Mikko Härmä,Tarja Porkka-Heiskanen,Tiina Paunio,Tiina Paunio +24 more
TL;DR: The results illustrate the utility of combining different analytical approaches to identify genetic determinants for traits related to sleep physiology, however, additional studies are needed in order to understand the roles of KLF6 and PCDH7 in sleep regulation.
Journal ArticleDOI
Bridging the Reciprocal Gap between Sleep and Fruit and Vegetable Consumption: A Review of the Evidence, Potential Mechanisms, Implications, and Directions for Future Work
TL;DR: An overview of experimental and observational studies assessing the relations between sleep and FV consumption from 52 human adult studies supports a non-linear association with adults sleeping the recommended 7–9 hours/day having the highest intakes of FV.
Journal ArticleDOI
Methodology and theoretical basis of forward genetic screening for sleep/wakefulness in mice
Chika Miyoshi,Staci Jakyong Kim,Takahiro Ezaki,Aya Ikkyu,Noriko Hotta-Hirashima,Satomi Kanno,Miyo Kakizaki,Mana Yamada,Shigeharu Wakana,Masashi Yanagisawa,Hiromasa Funato,Hiromasa Funato +11 more
TL;DR: A large-scale screening system using EEG/EMG-based sleep/wake monitoring with reliable parameters is established and the theoretical basis of forward genetics research for sleep in mice is discussed.
References
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Journal Article
A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms.
James Horne,Ostberg O +1 more
TL;DR: Although the questionnaire appears to be valid, further evaluation using a wider subject population is required, as sleep habits are an important déterminant of peak time there are other contibutory factors, and these appear to be partly covered by the questionnaire.
Journal ArticleDOI
Life between clocks: daily temporal patterns of human chronotypes.
TL;DR: It is predicted that the timing of sleep has changed during industrialization and that a majority of humans are sleep deprived during the workweek, and the implications are far ranging concerning learning, memory, vigilance, performance, and quality of life.
Journal ArticleDOI
Stability, Precision, and Near-24-Hour Period of the Human Circadian Pacemaker
Charles A. Czeisler,Jeanne F. Duffy,Theresa L. Shanahan,Emery N. Brown,Jude F. Mitchell,D. W. Rimmer,Joseph M. Ronda,Edward J. Silva,James S. Allan,Jonathan S. Emens,Derk-Jan Dijk,Richard E. Kronauer +11 more
TL;DR: In this article, the intrinsic period of the human circadian pacemaker averages 24.18 hours in both age groups, with a tight distribution consistent with other species, with important implications for understanding the pathophysiology of disrupted sleep in older people.
Journal ArticleDOI
Timing of human sleep: recovery process gated by a circadian pacemaker
TL;DR: The model shows that the experimental data are consistent with the concept of a single circadian pacemaker in humans, which has implications for the understanding of sleep as a restorative process and its timing with respect to day and night.