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Journal ArticleDOI

Glucose intolerance states in women with the polycystic ovary syndrome.

R. Pasquali, +1 more
- 01 Sep 2013 - 
- Vol. 36, Iss: 8, pp 648-653
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TLDR
argeted intervention studies focused on prevention and treatment of glucose intolerance states in PCOS are warranted and some insights on potential factors responsible for individual susceptibility are discussed.
Abstract
The polycystic ovary syndrome (PCOS), the most common hyperandrogenic disorder affecting 4–7% of women, is often associated with metabolic alterations, chiefly insulin resistance and obesity. Based on available scientific evidence, PCOS should be regarded as an independent risk for the development of glucose intolerance states. This short review summarizes the available literature on the prevalence and incidence of impaired glucose tolerance and Type 2 diabetes in this disorder. In addition, some insights on potential factors responsible for individual susceptibility are discussed. Targeted intervention studies focused on prevention and treatment of glucose intolerance states in PCOS are warranted.

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Citations
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Синдром поликистозных яичников. Официальное заявление Европейского общества эндокринологии

TL;DR: A critical endocrine on the debate on the definition of PCOS and summarises all major aspects related to aetiological factors, including early life events, potentially involved in the development of the disorder.
Journal ArticleDOI

Insulin and the polycystic ovary syndrome.

TL;DR: Metformin is the primary insulin-sensitising drug to be used as an adjuvant therapy to lifestyle modification in patients with insulin resistance and impaired glucose tolerance, as well as in those referred to infertility treatment, and glucagon-like peptide 1 analogues has a potential therapeutic use in obese PCOS women.
References
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Journal ArticleDOI

Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome

TL;DR: Since the 1990 NIH-sponsored conference on polycystic ovary syndrome, it has become appreciated that the syndrome encompasses a broader spectrum of signs and symptoms of ovarian dysfunction than those defined by the original diagnostic criteria.
Journal ArticleDOI

Men at risk: occupation and male infertility☆

TL;DR: There is accumulating evidence that workplace exposure to toxic substances contributes to male infertility, and men suffering from infertility problems may do well to look at their occupations, where exposure to certain substances may be a contributory factor.
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