Journal ArticleDOI
GRADE guidelines: 13. Preparing Summary of Findings tables and evidence profiles—continuous outcomes
Gordon H. Guyatt,Kristian Thorlund,Andrew D Oxman,Stephen D. Walter,Donald L. Patrick,Toshi A. Furukawa,Bradley C. Johnston,Paul J. Karanicolas,Elie A. Akl,Gunn Elisabeth Vist,Regina Kunz,Jan Brozek,Lawrence L. Kupper,Sandra L. Martin,Joerg J Meerpohl,Pablo Alonso-Coello,Robin Christensen,Holger J. Schünemann +17 more
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TLDR
Alternatives include presenting results in the units of the most popular or interpretable measure, converting to dichotomous measures and presenting relative and absolute effects, presenting the ratio of the means of intervention and control groups, and presenting the results in minimally important difference units.About:
This article is published in Journal of Clinical Epidemiology.The article was published on 2013-02-01. It has received 461 citations till now. The article focuses on the topics: Units of measurement.read more
Citations
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Exploring reasons for the observed inconsistent trial reports on intra-articular injections with hyaluronic acid in the treatment of osteoarthritis: Meta-regression analyses of randomized trials.
Mette Y. Johansen,Henriette Bahrt,Roy D. Altman,Else Marie Bartels,Carsten Bogh Juhl,Henning Bliddal,Hans Lund,Robin Christensen +7 more
TL;DR: Publishing bias and the risk of selective outcome reporting suggest only small clinical effect compared to saline, while intra-articular hyaluronic acid showed a better effect than intra-Articular saline on pain reduction in osteoarthritis.
Journal ArticleDOI
Plasma expanders for people with cirrhosis and large ascites treated with abdominal paracentesis
TL;DR: This review found no evidence of a difference in effect between plasma expansion versus no plasma expansion in people with cirrhosis and large ascites, and calculated the risk ratio or mean difference using the fixed-effect model and the random-effects model meta-analyses.
Journal ArticleDOI
Creating Clinical Practice Guidelines: Problems and Solutions
Journal ArticleDOI
Xiao Chai Hu Tang, a herbal medicine, for chronic hepatitis B
De Zhao Kong,Ning Liang,Ning Liang,Guan Lin Yang,Zhe Zhang,Yue Liu,Jing Li,Xue-Han Liu,Shibing Liang,Dimitrinka Nikolova,Janus Christian Jakobsen,Christian Gluud,Jianping Liu +12 more
TL;DR: The Chinese herbal medicine formula Xiao Chai Hu Tang formula has been used to decrease discomfort and replication of the virus in people with chronic hepatitis B but the benefits and harms have never been established with rigorous review methodology.
Journal ArticleDOI
External beam radiotherapy for unresectable hepatocellular carcinoma
Omar Abdel-Rahman,Zeinab Elsayed +1 more
TL;DR: The combined treatment with external beam radiotherapy plus transarterial chemoembolisation alone in people with unresectable hepatocellular carcinoma was associated with a higher risk of elevated total bilirubin and elevated alanine aminotransferase.
References
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Book
Statistical Power Analysis for the Behavioral Sciences
TL;DR: The concepts of power analysis are discussed in this paper, where Chi-square Tests for Goodness of Fit and Contingency Tables, t-Test for Means, and Sign Test are used.
Journal ArticleDOI
Development of a Rating Scale for Primary Depressive Illness
TL;DR: This is an account of further work on a rating scale for depressive states, including a detailed discussion on the general problems of comparing successive samples from a ‘population’, the meaning of factor scores, and the other results obtained.
Journal ArticleDOI
GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables
Gordon H. Guyatt,Andrew D Oxman,Elie A. Akl,Regina Kunz,Gunn Elisabeth Vist,Jan Brozek,Susan L Norris,Yngve Falck-Ytter,Paul Glasziou,Hans deBeer,Roman Jaeschke,David Rind,Joerg J Meerpohl,Philipp Dahm,Holger J. Schünemann +14 more
TL;DR: The GRADE process begins with asking an explicit question, including specification of all important outcomes, and provides explicit criteria for rating the quality of evidence that include study design, risk of bias, imprecision, inconsistency, indirectness, and magnitude of effect.
Journal ArticleDOI
GRADE guidelines: 3. Rating the quality of evidence
Howard Balshem,Mark Helfand,Mark Helfand,Holger J. Schünemann,Andrew D Oxman,Regina Kunz,Jan Brozek,Gunn Elisabeth Vist,Yngve Falck-Ytter,Joerg J Meerpohl,Susan L Norris,Gordon H. Guyatt +11 more
TL;DR: The approach of GRADE to rating quality of evidence specifies four categories-high, moderate, low, and very low-that are applied to a body of evidence, not to individual studies.
Related Papers (5)
GRADE guidelines: 7. Rating the quality of evidence—inconsistency
GRADE guidelines: 4. Rating the quality of evidence—study limitations (risk of bias)
GRADE guidelines: 6. Rating the quality of evidence-imprecision
Gordon H. Guyatt,Andrew D Oxman,Regina Kunz,Jan Brozek,Pablo Alonso-Coello,David Rind,Philip J. Devereaux,Victor M. Montori,Bo Freyschuss,Gunn Elisabeth Vist,Roman Jaeschke,John W Williams,Mohammad Hassan Murad,David A. Sinclair,Yngve Falck-Ytter,Joerg J Meerpohl,Craig Whittington,Kristian Thorlund,Jeffrey C Andrews,Holger J. Schünemann +19 more