Journal ArticleDOI
GRADE guidelines: 13. Preparing Summary of Findings tables and evidence profiles—continuous outcomes
Gordon H. Guyatt,Kristian Thorlund,Andrew D Oxman,Stephen D. Walter,Donald L. Patrick,Toshi A. Furukawa,Bradley C. Johnston,Paul J. Karanicolas,Elie A. Akl,Gunn Elisabeth Vist,Regina Kunz,Jan Brozek,Lawrence L. Kupper,Sandra L. Martin,Joerg J Meerpohl,Pablo Alonso-Coello,Robin Christensen,Holger J. Schünemann +17 more
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TLDR
Alternatives include presenting results in the units of the most popular or interpretable measure, converting to dichotomous measures and presenting relative and absolute effects, presenting the ratio of the means of intervention and control groups, and presenting the results in minimally important difference units.About:
This article is published in Journal of Clinical Epidemiology.The article was published on 2013-02-01. It has received 461 citations till now. The article focuses on the topics: Units of measurement.read more
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Relation of total sugars, fructose and sucrose with incident type 2 diabetes: a systematic review and meta-analysis of prospective cohort studies.
Christine S. Tsilas,Russell J. de Souza,Sonia Blanco Mejia,Arash Mirrahimi,Adrian I. Cozma,Viranda H. Jayalath,Vanessa Ha,Reem Tawfik,Marco Di Buono,Alexandra L Jenkins,Lawrence A. Leiter,Thomas M.S. Wolever,Joseph Beyene,Tauseef Khan,Cyril W.C. Kendall,David J.A. Jenkins,John L. Sievenpiper +16 more
TL;DR: Current evidence does not allow us to conclude that fructose-containing sugars independent of food form are associated with increased risk of type 2 diabetes, and confidence in the estimates was limited by evidence of serious inconsistency between studies for total sugars and fructose, and serious imprecision in the pooled estimates for all 3 sugar categories.
Journal ArticleDOI
Facilitating healthcare decisions by assessing the certainty in the evidence from preclinical animal studies.
Carlijn R. Hooijmans,Rob B. M. de Vries,Merel Ritskes-Hoitinga,Maroeska M. Rovers,Mariska M.G. Leeflang,Joanna IntHout,Kimberley E. Wever,Lotty Hooft,Hans de Beer,Ton Kuijpers,Malcolm R. Macleod,Emily S. Sena,Gerben ter Riet,Rebecca L. Morgan,Kristina A. Thayer,Andrew A. Rooney,Gordon H. Guyatt,Holger J. Schünemann,Miranda W. Langendam +18 more
TL;DR: How the GRADE approach could be used to rate the certainty in the evidence of preclinical animal studies in the context of therapeutic interventions is presented and the methodological challenges identified are discussed.
Journal ArticleDOI
Management of major organ involvement of Behçet’s syndrome: a systematic review for update of the EULAR recommendations
Yesim Ozguler,Pietro Leccese,Robin Christensen,Robin Christensen,Sinem Nihal Esatoglu,Dongsik Bang,Bahram Bodaghi,Aykut Ferhat Celik,Farida Fortune,Julien Gaudric,Ahmet Gül,Ina Kötter,Alfred Mahr,Robert J. Moots,Jutta G Richter,David Saadoun,Carlo Salvarani,Francesco Scuderi,Petros P. Sfikakis,Aksel Siva,Miles Stanford,Ilknur Tugal-Tutkun,Richard P. West,Sebahattin Yurdakul,Ignazio Olivieri,Hasan Yazici,Gulen Hatemi +26 more
TL;DR: The majority of studies related to major organ involvement that informed the updated EULAR recommendations for the management of BS were observational studies, including studies with beneficial results for refractory uveitis.
Journal ArticleDOI
Fructose intake and risk of gout and hyperuricemia: a systematic review and meta-analysis of prospective cohort studies.
Joseph Jamnik,Sara Rehman,Sonia Blanco Mejia,Russell J. de Souza,Tauseef Khan,Lawrence A. Leiter,Thomas M.S. Wolever,Cyril W.C. Kendall,D. J. A. Jenkins,John L. Sievenpiper +9 more
TL;DR: Fructose consumption was associated with an increased risk of developing gout in predominantly white health professionals and its food sources in the development of gout and hyperuricemia.
Journal ArticleDOI
Presentation of Benefits and Harms in US Cancer Screening and Prevention Guidelines: Systematic Review.
Tanner J. Caverly,Rodney A. Hayward,Elyse N. Reamer,Brian J. Zikmund-Fisher,Daniel Connochie,Michele Heisler,Angela Fagerlin +6 more
TL;DR: Improved presentation of benefits and harms in guidelines would better ensure that clinicians and patients have access to the information required for making informed decisions.
References
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Book
Statistical Power Analysis for the Behavioral Sciences
TL;DR: The concepts of power analysis are discussed in this paper, where Chi-square Tests for Goodness of Fit and Contingency Tables, t-Test for Means, and Sign Test are used.
Journal ArticleDOI
Development of a Rating Scale for Primary Depressive Illness
TL;DR: This is an account of further work on a rating scale for depressive states, including a detailed discussion on the general problems of comparing successive samples from a ‘population’, the meaning of factor scores, and the other results obtained.
Journal ArticleDOI
GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables
Gordon H. Guyatt,Andrew D Oxman,Elie A. Akl,Regina Kunz,Gunn Elisabeth Vist,Jan Brozek,Susan L Norris,Yngve Falck-Ytter,Paul Glasziou,Hans deBeer,Roman Jaeschke,David Rind,Joerg J Meerpohl,Philipp Dahm,Holger J. Schünemann +14 more
TL;DR: The GRADE process begins with asking an explicit question, including specification of all important outcomes, and provides explicit criteria for rating the quality of evidence that include study design, risk of bias, imprecision, inconsistency, indirectness, and magnitude of effect.
Journal ArticleDOI
GRADE guidelines: 3. Rating the quality of evidence
Howard Balshem,Mark Helfand,Mark Helfand,Holger J. Schünemann,Andrew D Oxman,Regina Kunz,Jan Brozek,Gunn Elisabeth Vist,Yngve Falck-Ytter,Joerg J Meerpohl,Susan L Norris,Gordon H. Guyatt +11 more
TL;DR: The approach of GRADE to rating quality of evidence specifies four categories-high, moderate, low, and very low-that are applied to a body of evidence, not to individual studies.
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GRADE guidelines: 6. Rating the quality of evidence-imprecision
Gordon H. Guyatt,Andrew D Oxman,Regina Kunz,Jan Brozek,Pablo Alonso-Coello,David Rind,Philip J. Devereaux,Victor M. Montori,Bo Freyschuss,Gunn Elisabeth Vist,Roman Jaeschke,John W Williams,Mohammad Hassan Murad,David A. Sinclair,Yngve Falck-Ytter,Joerg J Meerpohl,Craig Whittington,Kristian Thorlund,Jeffrey C Andrews,Holger J. Schünemann +19 more