Journal ArticleDOI
Grating-based X-ray phase contrast for biomedical imaging applications
Franz Pfeiffer,Julia Herzen,Julia Herzen,Marian Willner,Michael Chabior,Sigrid Auweter,Maximilian F. Reiser,Fabian Bamberg +7 more
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TLDR
The theoretical concepts to extend grating-based multimodal radiography to quantitative transmission, phase-contrast, and dark-field scattering computed tomography are discussed.Abstract:
In this review article we describe the development of grating-based X-ray phase-contrast imaging, with particular emphasis on potential biomedical applications of the technology. We review the basics of image formation in grating-based phase-contrast and dark-field radiography and present some exemplary multimodal radiography results obtained with laboratory X-ray sources. Furthermore, we discuss the theoretical concepts to extend grating-based multimodal radiography to quantitative transmission, phase-contrast, and dark-field scattering computed tomography.read more
Citations
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Journal ArticleDOI
X-ray phase-contrast imaging
TL;DR: X-ray imaging is a standard tool for the non-destructive inspection of the internal structure of samples and finds application in a vast diversity of fields: medicine, biology, many engineering disciplines, palaeontology and earth sciences as discussed by the authors.
Journal ArticleDOI
X-ray phase contrast imaging: From synchrotrons to conventional sources
TL;DR: The phase-based approaches can increase the contrast of all details, and enable the detection of features classically considered "X-ray invisible" as discussed by the authors, which is the main limitation of low attenuation differences.
Journal ArticleDOI
Large field-of-view tiled grating structures for X-ray phase-contrast imaging.
Tobias J. Schröter,Frieder Koch,Pascal Meyer,Danays Kunka,Jan Meiser,Konstantin Willer,Lukas B. Gromann,Fabio De Marco,Julia Herzen,Peter B. Noël,Andre Yaroshenko,Andreas Hofmann,Franz Pfeiffer,Jürgen Mohr +13 more
TL;DR: First results of a phase-contrast scanning setup with a full FoV of 384 mm × 24 mm show the suitability of this method and investigates theoretically the accuracy needed for a tiling process in all degrees of freedom by applying a simulation approach.
Journal ArticleDOI
Helical X-ray phase-contrast computed tomography without phase stepping
Mathias Marschner,Marian Willner,Guillaume Potdevin,Andreas Fehringer,Peter B. Noël,Franz Pfeiffer,Julia Herzen +6 more
TL;DR: A novel scan technique is demonstrated, which directly allows the determination of the phase signal without a phase-stepping procedure, based on moiré fringe scanning, which allows fast data acquisition in radiographic applications such as mammography or in-line product analysis.
Journal ArticleDOI
AHA classification of coronary and carotid atherosclerotic plaques by grating-based phase-contrast computed tomography.
Holger Hetterich,Nicole Webber,Marian Willner,Julia Herzen,Lorenz Birnbacher,Alexander Hipp,Mathias Marschner,Sigrid Auweter,Christopher Habbel,Ulrich Schüller,Fabian Bamberg,Birgit Ertl-Wagner,Franz Pfeiffer,Tobias Saam +13 more
TL;DR: It is indicated that gb-PCCT can reliably classify atherosclerotic plaques according to modified AHA criteria with excellent agreement to histopathology and phase-contrast CT can detect and differentiate AHA plaque types.
References
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Journal ArticleDOI
Phase retrieval and differential phase-contrast imaging with low-brilliance X-ray sources
TL;DR: In this article, a setup consisting of three transmission gratings can efficiently yield quantitative differential phase-contrast images with conventional X-ray tubes, which can be scaled up to large fields of view.
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Phase-contrast imaging using polychromatic hard X-rays
TL;DR: In this paper, a simplified scheme for phase-contrast imaging based on an X-ray source having high spatial (but essentially no chromatic) coherence is presented. But the method is not suitable for large areas of irradiation, and it can operate with a lower absorbed dose than traditional Xray imaging techniques, and should find broad application in clinical, biological and industrial settings.
Journal ArticleDOI
X-ray phase imaging with a grating interferometer.
Timm Weitkamp,Ana Diaz,Christian David,Franz Pfeiffer,Marco Stampanoni,Peter Cloetens,Eric Ziegler +6 more
TL;DR: Using a high-efficiency grating interferometer for hard X rays (10-30 keV) and a phase-stepping technique, separate radiographs of the phase and absorption profiles of bulk samples can be obtained from a single set of measurements.
Journal ArticleDOI
Hard-X-ray dark-field imaging using a grating interferometer
Franz Pfeiffer,Franz Pfeiffer,Martin Bech,Oliver Bunk,P. Kraft,E. F. Eikenberry,Christian Brönnimann,Christian Grünzweig,Christian David +8 more
TL;DR: This letter reports a new approach on the basis of a grating interferometer that can efficiently yield dark-field scatter images of high quality, even with conventional X-ray tube sources and is fully compatible with conventional transmission radiography and a recently developed hard-X-ray phase-contrast imaging scheme.