Journal ArticleDOI
Guar and diabetes.
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This article is published in The Lancet.The article was published on 1979-03-17. It has received 214 citations till now. The article focuses on the topics: Guar.read more
Citations
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IFN‐γ activation of mesenchymal stem cells for treatment and prevention of graft versus host disease
David Polchert,Justin Sobinsky,G. W. Douglas,Martha Kidd,Ada Moadsiri,Eduardo Reina,Kristyn Genrich,Swati Mehrotra,Suman Setty,Brett Smith,Amelia Bartholomew +10 more
TL;DR: It is shown that bone marrow‐isolated MSC can suppress the development of GVHD if given after donor T cell recognition of antigen, and activated MSC could prevent GV HD mortality when given at the time of bone marrow transplantation.
Journal ArticleDOI
The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation.
Vincent T. Ho,Robert J. Soiffer +1 more
TL;DR: T-cell depletion (TCD) of the donor graft offers the potential for prevention of GVHD without donor graft depletion.
Journal ArticleDOI
Combined histocompatibility leukocyte antigen-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: the induction of allograft tolerance through mixed lymphohematopoietic chimerism.
Thomas R. Spitzer,Francis L. Delmonico,Nina Tolkoff-Rubin,Steven L. McAfee,Robert Sackstein,Susan L. Saidman,Christine Colby,Megan Sykes,David H. Sachs,Cosimi Ab +9 more
TL;DR: This is the first report of the deliberate induction of mixed lymphohematopoietic chimerism after a nonmyeloablative preparative regimen to treat a hematological malignancy and to provide allotolerance for a solid organ transplant.
Journal ArticleDOI
Medicinal plants with hypoglycemic activity.
Atta-ur-Rahman,Khurshid Zaman +1 more
TL;DR: This review summarises the literature on the antidiabetic activity of 343 medicinal plants reputed in the indigenous system of medicine or in which the pharmacological activity has been scientifically demonstrated.
Journal ArticleDOI
Animal model of Gaucher's disease from targeted disruption of the mouse glucocerebrosidase gene.
Victor L. J. Tybulewicz,Victor L. J. Tybulewicz,Michel L. Tremblay,Michel L. Tremblay,LaMarca,Rob Willemsen,B. K. Stubblefield,S. Winfield,B. Zablocka,E. Sidransky,Brian M. Martin,Sing-Ping Huang,K. A. Mintzer,Heiner Westphal,Richard C. Mulligan,Edward I. Ginns +15 more
TL;DR: An animal model for Gaucher's disease is generated by creating a null allele in embryonic stem cells through gene targeting and using these genetically modified cells to establish a mouse strain carrying the mutation.
References
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Journal ArticleDOI
Dietary fibres, fibre analogues, and glucose tolerance: importance of viscosity.
David J.A. Jenkins,Thomas M.S. Wolever,Anthony R. Leeds,Miguel A. Gassull,P Haisman,Dilawari Jb,D V Goff,Metz Gl,K. G. M. M. Alberti +8 more
TL;DR: Viscous types of dietary fibre are most likely to be therapeutically useful in modifying postprandial hyperglycaemia.
Journal ArticleDOI
Beneficial effects of a high carbohydrate, high fiber diet on hyperglycemic diabetic men
TL;DR: A high carbohydrate diet with generous amounts of dietary fiber may be the treatment of choice of diabetic patients requiring sulfonylureas or less than 30 units of insulin per day.
Journal ArticleDOI
High-fiber diets in the treatment of diabetes mellitus.
TL;DR: It is indicated that substantial changes in fiber content of the diabetic diet may lead to marked changes in diabetic control and that increasing dietary fiber may be a useful means of lowering plasma glucose in some diabetic patients.
Journal ArticleDOI
TREATMENT OF DIABETES WITH GUAR GUM: Reduction of Urinary Glucose Loss in Diabetics
DavidJ.A. Jenkins,T. Derek,R. Hockaday,Richard Howarth,E.C. Apling,Thomas M.S. Wolever,A.R. Leeds,Susan Bacon,Jang Dilawari +8 more
TL;DR: When nine diabetic patients supplemented either their normal home diets or metabolic ward diets with 25 g guar gum daily for 5 or 7 days their mean urinary glucose excretion fell, and gel-forming, unabsorbable carbohydrate may be a useful adjunct to anti-diabetic therapy, irrespective of the type of treatment or insulin dosage used.
Journal ArticleDOI
Survey of dietary policy and management in British diabetic clinics.
TL;DR: Questions about dietary policy were sent to 471 physicians in diabetic clinics throughout the United Kingdom, and usable replies were received from 281; there is uncertainty about the ideal dietary policy for diabetics and the best way of helping patients to follow the regimen prescribed.
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