Hippocampus contributions to food intake control: mnemonic, neuroanatomical, and endocrine mechanisms
Scott E. Kanoski,Harvey J. Grill +1 more
TLDR
The data reviewed here support the perspective that neurons in multiple hippocampal subregions constitute an important neural substrate linking the external context, the internal context, and mnemonic and cognitive information to control both appetitive and ingestive behavior.About:
This article is published in Biological Psychiatry.The article was published on 2017-05-01 and is currently open access. It has received 189 citations till now. The article focuses on the topics: Context (language use) & Neural substrate.read more
Citations
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Leptin and the maintenance of elevated body weight.
Warren Pan,Martin G. Myers +1 more
TL;DR: It is possible that increased LEPR signalling may be increased (rather than impaired) in common obesity, suggesting that any obesity-associated defects in leptin action must result from lesions somewhere other than the initial LEPR signal.
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The Emerging Science of Interoception: Sensing, Integrating, Interpreting, and Regulating Signals within the Self.
Wen G. Chen,Dana Schloesser,Angela M. Arensdorf,Janine M. Simmons,Changhai Cui,Rita J. Valentino,James W. Gnadt,Lisbeth Nielsen,Coryse St Hillaire-Clarke,Victoria M. Spruance,Todd S. Horowitz,Yolanda F. Vallejo,Helene M. Langevin +12 more
TL;DR: Interoception refers to the representation of the internal states of an organism, and includes the processes by which it senses, interprets, integrates, and regulates signals from within itself as discussed by the authors.
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GLP-1 and weight loss: unraveling the diverse neural circuitry.
TL;DR: In some of these nuclei [VTA, NAc, and vHP], GLP-1R activation reduces food intake and body weight without concomitant nausea responses, suggesting that targeting these specific pathways may be of particular interest for future obesity pharmacotherapy.
Journal ArticleDOI
Gut vagal sensory signaling regulates hippocampus function through multi-order pathways
Andrea N. Suarez,Ted M. Hsu,Ted M. Hsu,Clarissa M. Liu,Emily E. Noble,Alyssa M. Cortella,Emily M Nakamoto,Joel D. Hahn,Guillaume de Lartigue,Scott E. Kanoski +9 more
TL;DR: It is shown that selective GI vagal sensory/afferent ablation in rats impairs HPC-dependent episodic and spatial memory, effects associated with reduced HPC neurotrophic and neurogenesis markers, thereby identifying a previously unknown role for the gut–brain axis in memory control.
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Central nervous pathways of insulin action in the control of metabolism and food intake
Stephanie Kullmann,André Kleinridders,Dana M. Small,Dana M. Small,Andreas Fritsche,Hans-Ulrich Häring,Hubert Preissl,Martin Heni +7 more
TL;DR: Overall, current findings highlight the role of insulin action in the brain and its consequences on peripheral metabolism and cognition and improving central insulin action could represent a therapeutic option for people at an increased risk of developing metabolic and cognitive diseases.
References
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