Journal ArticleDOI
Hot-melt extrusion: Highlighting recent advances in pharmaceutical applications
TLDR
This review channels to a holistic perspective of several equipment components, processing requirements, materials used in HME, and various drug delivery systems utilizing HME in recent years and gives a comprehensive treatise on several novel opportunities and innovations.About:
This article is published in Journal of Drug Delivery Science and Technology.The article was published on 2021-06-01. It has received 26 citations till now.read more
Citations
More filters
Journal ArticleDOI
Recent trends in the application of essential oils: The next generation of food preservation and food packaging
Srutee Rout,Srushti Tambe,Rameshwar K. Deshmukh,Suraj N. Mali,Jorddy Nevez Cruz,Prem Prakash Srivastav,Purnima D. Amin,Kirtiraj K. Gaikwad,Eloisa Helena A. Andrade,Mozaniel Santana de Oliveira +9 more
TL;DR: In this paper , the authors discuss the recent developments in the application of EOs from plants and spices as antimicrobial agents for food preservation and shelf-life augmentation and highlight new developments in encapsulating strategies to get beyond some significant intrinsic constraints, such as low water solubility, volatility, bioavailability and stability in food systems.
Journal ArticleDOI
Eudragit®: A Versatile Family of Polymers for Hot Melt Extrusion and 3D Printing Processes in Pharmaceutics.
TL;DR: In this article, the authors highlight the possibilities of Eudragit polymers in HME and 3D printing, whether alone or in blends, discussing their prominence in the development of innovative modified drug release systems.
Peer ReviewDOI
Potential of Flax Fiber Reinforced Biopolymer Composites for Cross-Arm Application in Transmission Tower: A Review
M. R. M. Asyraf,Mohamad Ridzwan Ishak,Mohd Nor Faiz Norrrahim,A. Amir,N. Mohd Nurazzi,R.A. Ilyas,Mochamad Asrofi,M. Rafidah,Muhammad Rizal Razman +8 more
Journal ArticleDOI
Recent Advances in Amorphous Solid Dispersions: Preformulation, Formulation Strategies, Technological Advancements and Characterization
Srushti Tambe,Divya Jain,Saikishore Meruva,Gopinath Rongala,Abhishek Juluri,Girish Nihalani,Hemanth K. Mamidi,Pavan Nukala,Pradeep Kumar Bolla +8 more
TL;DR: A review of the recent advancements in the field of ASDs with respect to formulation approaches, methods of preparation, and advanced characterization techniques can be found in this article , where the authors highlight some of the most important developments in this field.
Journal ArticleDOI
Hot-melt extrudability of amorphous solid dispersions of flubendazole-copovidone: An exploratory study of the effect of drug loading and the balance of adjuvants on extrudability and dissolution.
João M. C. de Assis,Eduardo José Barbosa,Vinícius D.N. Bezzon,Felipe Rebello Lourenço,Flávio M S Carvalho,J. R. Matos,Nadia Araci Bou-Chacra,Chris J. Benmore,Stephen R. Byrn,Fanny N. Costa,Gabriel L B de Araujo +10 more
TL;DR: In this paper , the authors evaluated the influence of adjuvants and drug loading on the development of amorphous solid dispersion of flubendazole-copovidone by hot-melt extrusion.
References
More filters
Journal ArticleDOI
Improving drug solubility for oral delivery using solid dispersions.
TL;DR: The historical background and definitions of the various systems including eutectic mixtures, solid dispersions and solid solutions, as well as the production, the different carriers and the methods used for the characterization of solid dispersion are outlined.
Journal ArticleDOI
Mechanochemistry: opportunities for new and cleaner synthesis
Stuart L. James,Christopher J. Adams,Carsten Bolm,Dario Braga,Paul Collier,Tomislav Friščić,Fabrizia Grepioni,Kenneth D. M. Harris,Geoff Hyett,William Jones,Anke Krebs,James Mack,Lucia Maini,A. Guy Orpen,Ivan P. Parkin,William C. Shearouse,Jonathan W. Steed,Daniel C. Waddell +17 more
TL;DR: Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes, supramolecular aspects and characterization methods.
Journal ArticleDOI
What is the true solubility advantage for amorphous pharmaceuticals
Bruno C. Hancock,Michael Parks +1 more
TL;DR: Amorphous pharmaceuticals are markedly more soluble than their crystalline counterparts, however, their experimental solubility advantage is typically less than that predicted from simplethermodynamic considerations.
Journal ArticleDOI
Pharmaceutical Cocrystals and Their Physicochemical Properties
Nate Schultheiss,Ann Newman +1 more
TL;DR: The advances made over the last 10 years pertaining to physical and chemical property improvements through pharmaceutical cocrystalline materials will be highlighted and discussed to draw closer the fields of crystal engineering and pharmaceutical sciences.
Journal ArticleDOI
Salt formation to improve drug solubility.
TL;DR: Physicochemical principles of salt solubility are presented, with special reference to the influence of pH-solubility profiles of acidic and basic drugs on salt formation and dissolution.