Impact of Transcatheter Aortic Valve Durability on Life Expectancy in Low-Risk Patients With Severe Aortic Stenosis.
Derrick Y. Tam,Derrick Y. Tam,Harindra C. Wijeysundera,Harindra C. Wijeysundera,Harindra C. Wijeysundera,David Naimark,Mario Gaudino,John G. Webb,David Cohen,Stephen E. Fremes,Stephen E. Fremes +10 more
TLDR
According to simulation models, the durability of TAVR valves must be 70% shorter than that of surgical valves to result in reduced life expectancy in patients with demographics similar to those of recent trials, but in younger low-risk patients, valve durability must be weighed against other patient factors such as life expectancy.Abstract:
Background: Recent clinical trial results showed that transcatheter aortic valve replacement (TAVR) is noninferior and may be superior to surgical aortic valve replacement (SAVR) for mortality, str...read more
Citations
More filters
Journal ArticleDOI
Outcomes 2 Years After Transcatheter Aortic Valve Replacement in Patients at Low Surgical Risk.
Martin B. Leon,Michael J. Mack,Rebecca T. Hahn,Vinod H. Thourani,Raj Makkar,Susheel Kodali,Maria Alu,Mahesh V. Madhavan,Katherine H. Chau,Mark J. Russo,Samir R. Kapadia,S. Chris Malaisrie,David J. Cohen,Philipp Blanke,Jonathon Leipsic,Mathew R. Williams,James M. McCabe,David L. Brown,Vasilis Babaliaros,Scott M. Goldman,Howard C. Herrmann,Wilson Y. Szeto,Philippe Généreux,Ashish Pershad,Michael T. Lu,John G. Webb,Craig R. Smith,Philippe Pibarot,Partner Investigators +28 more
TL;DR: The safety and effectiveness of transcatheter aortic valve replacement (TAVR) versus surgery for the primary endpoint of death, stroke, or rehospitalization at 1 year was evaluated in the PARTNER 3 trial as discussed by the authors.
Journal Article
Abstract 19391: Early Structural Valve Deterioration of Mitroflow Aortic Bioprosthesis : Mode, Incidence and Impact on Outcome in a Large Cohort of Patients
Thomas Senage,Jean Christian Roussel,Yohann Foucher,Christian Perigaud,Antoine Mugniot,Thierry Le Tourneau +5 more
TL;DR: In this article, the authors assess the incidence, the mode and the impact of structural valve deterioration on outcome in a large series of Mitroflow aortic valve replacement (AVR) patients.
Journal ArticleDOI
Transcatheter Aortic Valve Replacement in Low-Risk, Young Patients: Natural Expansion or Cause for Concern?
George Hanzel,Bernard J. Gersh +1 more
Journal ArticleDOI
A biomimetic multilayered polymeric material designed for heart valve repair and replacement.
Ming Sun,Mohamed A Elkhodiry,Lei Shi,Ying Ying Xue,M.H. Abyaneh,Alexander P. Kossar,Caroline Giuglaris,Samuel L. Carter,Richard Li,Emile A. Bacha,Giovanni Ferrari,Jeffrey W. Kysar,K. Myers,David Kalfa +13 more
TL;DR: In this paper , a biomimetic multilayered material (BMM) was designed to replicate the native valve leaflets, which exhibited an anisotropic behavior and a closer mechanical performance to the aortic leaflets.
References
More filters
Journal ArticleDOI
Transcatheter versus Surgical Aortic-Valve Replacement in High-Risk Patients
Craig R. Smith,Martin B. Leon,Michael J. Mack,D. Craig Miller,Jeffrey W. Moses,Lars G. Svensson,E. Murat Tuzcu,John G. Webb,Gregory P. Fontana,Raj Makkar,Mathew R. Williams,Todd M. Dewey,Samir R. Kapadia,Vasilis Babaliaros,Vinod H. Thourani,Paul J. Corso,Augusto D. Pichard,Joseph E. Bavaria,Howard C. Herrmann,Jodi J. Akin,William N. Anderson,Duolao Wang,Stuart J. Pocock +22 more
TL;DR: In high-risk patients with severe aortic stenosis, transcatheter and surgical procedures for aorti-valve replacement were associated with similar rates of survival at 1 year, although there were important differences in periprocedural risks.
Journal ArticleDOI
Balance diagnostics for comparing the distribution of baseline covariates between treatment groups in propensity-score matched samples
TL;DR: Methods to determine the sampling distribution of the standardized difference when the true standardized difference is equal to zero are described, thereby allowing one to determined the range of standardized differences that are plausible with the propensity score model having been correctly specified.
Journal ArticleDOI
Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients.
Martin B. Leon,Craig R. Smith,Michael J. Mack,Michael J. Mack,Rajendra Makkar,Lars G. Svensson,Susheel Kodali,Vinod H. Thourani,Murat Tuzcu,D. Craig Miller,Howard C. Herrmann,Darshan Doshi,David J. Cohen,Augusto D. Pichard,Samir R. Kapadia,Todd M. Dewey,Vasilis Babaliaros,Wilson Y. Szeto,Mathew R. Williams,Dean J. Kereiakes,Alan Zajarias,Kevin L. Greason,Brian Whisenant,Robert W. Hodson,Jeffrey W. Moses,Alfredo Trento,David L. Brown,William F. Fearon,Philippe Pibarot,Rebecca T. Hahn,Wael A. Jaber,William N. Anderson,Maria Alu,John G. Webb +33 more
TL;DR: In intermediate-risk patients, TAVR was similar to surgical aortic-valve replacement with respect to the primary end point of death or disabling stroke; surgery resulted in fewer major vascular complications and less paravalvular aorta regurgitation.
Journal ArticleDOI
Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients
Michael J. Mack,Martin B. Leon,Vinod H. Thourani,Raj Makkar,Susheel Kodali,Mark J. Russo,Samir R. Kapadia,S. Chris Malaisrie,David J. Cohen,Philippe Pibarot,Jonathon Leipsic,Rebecca T. Hahn,Philipp Blanke,Mathew R. Williams,James M. McCabe,David L. Brown,Vasilis Babaliaros,Scott M. Goldman,Wilson Y. Szeto,Philippe Généreux,Ashish Pershad,Stuart J. Pocock,Maria Alu,John G. Webb,Craig R. Smith +24 more
TL;DR: Among patients with severe aortic stenosis who were at low surgical risk, the rate of the composite of death, stroke, or rehospitalization at 1 year was significantly lower with TAVR than with surgery.
Journal ArticleDOI
Transcatheter aortic-valve replacement with a self-expanding valve in low-risk patients
Jeffrey J. Popma,G. Michael Deeb,Steven J. Yakubov,Mubashir Mumtaz,Hemal Gada,Daniel O'Hair,Tanvir Bajwa,John Heiser,William Merhi,Neal S. Kleiman,Judah Askew,Paul Sorajja,Joshua Rovin,Stanley Chetcuti,David H. Adams,P.S. Teirstein,George L. Zorn,John K. Forrest,Didier Tchetche,Jon R. Resar,Antony Walton,Nicolo Piazza,Basel Ramlawi,Newell Robinson,George Petrossian,Thomas G. Gleason,Jae K. Oh,Michael J. Boulware,Hongyan Qiao,Andrew S. Mugglin,Michael J. Reardon +30 more
TL;DR: In patients with severe aortic stenosis who were at low surgical risk, TAVR with a self‐expanding supraannular bioprosthesis was noninferior to surgery with respect to the composite end point of death or disabling stroke at 24 months.
Related Papers (5)
Durability and clinical outcomes of transcatheter aortic valve replacement for failed surgical bioprostheses
Incidence of Long-Term Structural Valve Dysfunction and Bioprosthetic Valve Failure After Transcatheter Aortic Valve Replacement.
Marco Barbanti,Giuliano Costa,Paolo Zappulla,Denise Todaro,Andrea Picci,Giulia Rapisarda,Emanuela Di Simone,Rita Sicuso,Sergio Buccheri,Simona Gulino,Gerlando Pilato,Ketty La Spina,Paolo D'Arrigo,Roberto Valvo,Antonino Indelicato,Daniela Giannazzo,Sebastiano Immè,Claudia Tamburino,Martina Patanè,Carmelo Sgroi,Angelo Giuffrida,Danilo Trovato,Ines Monte,Wanda Deste,Piera Capranzano,Davide Capodanno,Corrado Tamburino +26 more
Structural Deterioration of Transcatheter Versus Surgical Aortic Valve Bioprostheses in the PARTNER-2 Trial.
Philippe Pibarot,Julien Ternacle,Wael A. Jaber,Erwan Salaun,Abdellaziz Dahou,Federico M. Asch,Neil J. Weissman,L. Leonardo Rodriguez,Ke Xu,Mohamed-Salah Annabi,Ezequiel Guzzetti,Jonathan Beaudoin,Mathieu Bernier,Jonathon Leipsic,Philipp Blanke,Marie-Annick Clavel,Erin Rogers,Maria Alu,Pamela S. Douglas,Raj Makkar,D. Craig Miller,Samir R. Kapadia,Michael J. Mack,John G. Webb,Susheel Kodali,Craig R. Smith,Howard C. Herrmann,Vinod H. Thourani,Martin B. Leon,Rebecca T. Hahn,Partner Investigators +30 more