Journal ArticleDOI
In vitro screening for anthelmintic and antitumour activity of ethnomedicinal plants from Thailand.
Korakot Atjanasuppat,Weerah Wongkham,Puttinan Meepowpan,Prasat Kittakoop,Prasert Sobhon,A. Bartlett,P. J. Whitfield +6 more
TLDR
The plant species screened in this research was recorded by several indigenous medicinal practitioners as antiparasitic, anticancer and/or related activities to the human major organ system.About:
This article is published in Journal of Ethnopharmacology.The article was published on 2009-06-25. It has received 108 citations till now. The article focuses on the topics: Anthelmintic & Piper chaba.read more
Citations
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Journal ArticleDOI
Piper Species: A Comprehensive Review on Their Phytochemistry, Biological Activities and Applications.
Bahare Salehi,Zainul Amiruddin Zakaria,Rabin Gyawali,Salam A. Ibrahim,Jovana Rajkovic,Zabta Khan Shinwari,Tariq Khan,Javad Sharifi-Rad,Adem Ozleyen,Elif Turkdonmez,Marco Valussi,Tugba Boyunegmez Tumer,Lianet Monzote Fidalgo,Miquel Martorell,William N. Setzer +14 more
TL;DR: The functional properties of Piper plants/extracts/active components the antiproliferative, anti-inflammatory, and neuropharmacological activities of the extracts and extract-derived bioactive constituents are thought to be key effects for the protection against chronic conditions.
Journal ArticleDOI
Bioactive compounds from medicinal plants: Focus on Piper species
TL;DR: New discoveries related to the phytochemistry and biological activities of bioactive compounds from Piper species are reviewed for further clinical applications, which could pave the way for the proper therapeutic use ofBioactive compounds and extracts from this plant species.
Journal ArticleDOI
Chemical constituents and biological research on plants in the genus Curcuma
Wen Sun,Sheng Wang,Wenwen Zhao,Chuanhong Wu,Shuhui Guo,Hongwei Gao,Hongxun Tao,Jin-Jian Lu,Yitao Wang,Xiuping Chen +9 more
TL;DR: This review comprehensively summarizes the current knowledge on the chemistry and briefly discusses the biological activities of Curcuma species, with emphasis on anti-inflammatory and antitumor activities.
Journal ArticleDOI
In vitro antioxidant and antiproliferative activities of methanolic plant part extracts of Theobroma cacao.
TL;DR: This study indicates that T. cacao methanolic extracts have a cytotoxic effect in cancer cells, but not in normal cells.
Journal ArticleDOI
Seed Oil of Brucea javanica Induces Apoptotic Death of Acute Myeloid Leukemia Cells via Both the Death Receptors and the Mitochondrial-Related Pathways.
TL;DR: This study provided strong evidence for the first time that BJO induced apoptosis of both cultured and primary AML cells and intravenous injection of BJO significantly inhibited U937 tumor growth in the xenograft mouse model, suggesting that B JO may have a therapeutic role in the treatment of human leukemia.
References
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New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening
Philip Skehan,Ritsa Storeng,Dominic A. Scudiero,Anne Monks,James B. McMahon,David T. Vistica,Jonathan T. Warren,Heidi R. Bokesch,Susan Kenney,Michael R. Boyd +9 more
TL;DR: The SRB assay provides a sensitive measure of drug-induced cytotoxicity, is useful in quantitating clonogenicity, and is well suited to high-volume, automated drug screening.
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Anti-tumour and antioxidant activity of natural curcuminoids
TL;DR: Curcumin III is the most active of the curcuminoids present in turmeric, indicated by the ability of these compounds to suppress the superoxide production by macrophages activated with phorbol-12-myristate-13-acetate (PMA).
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Biological activities of Curcuma longa L.
TL;DR: An overview of the pharmacological activities of C. longa L., showing its importance, and experiments showing the anti-parasitic, anti-inflammatory potency of curcumin and extracts of this plant by parenteral and oral application in animal models.
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Probit analysis of preference data
TL;DR: A probit analysis method is presented for the analysis of preference data from a behavioural assay of animals, where responses were observed as animals' cheice between the treatment and control sides or areas, and a preferable experimental design was formulated.
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Immunomodulatory and antitumor activity of Piper longum Linn. and piperine.
E.S Sunila,G Kuttan +1 more
TL;DR: Administration of alcoholic extract of Piper longum as well as piperine could inhibit the solid tumor development in mice induced with DLA cells and increase the life span of mice bearing Ehrlich ascites carcinoma tumor to 37.3 and 58.8%, respectively.