Journal ArticleDOI
Integrated nanohole array surface plasmon resonance sensing device using a dual-wavelength source
Carlos Escobedo,Serge Vincent,A. I. K. Choudhury,J. Campbell,Alexandre G. Brolo,David Sinton,Reuven Gordon +6 more
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In this paper, the authors demonstrate a compact integrated nanohole array-based surface plasmon resonance sensing device, which includes a LED light source, driving circuitry, CCD detector, microfluidic network and computer interface, all assembled from readily available commercial components.Abstract:
In this paper, we demonstrate a compact integrated nanohole array-based surface plasmon resonance sensing device. The unit includes a LED light source, driving circuitry, CCD detector, microfluidic network and computer interface, all assembled from readily available commercial components. A dual-wavelength LED scheme was implemented to increase spectral diversity and isolate intensity variations to be expected in the field. The prototype shows bulk sensitivity of 266 pixel intensity units/RIU and a limit of detection of 6 ? 10?4 RIU. Surface binding tests were performed, demonstrating functionality as a surface-based sensing system. This work is particularly relevant for low-cost point-of-care applications, especially those involving multiple tests and field studies. While nanohole arrays have been applied to many sensing applications, and their suitability to device integration is well established, this is the first demonstration of a fully integrated nanohole array-based sensing device.read more
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Surface Plasmon Resonance Optical Sensor: A Review on Light Source Technology
TL;DR: The trend of SPR sensor configurations, as well as its methodology and optical designs are strongly influenced by the development of light source technology as a critical component, which simultaneously offer new underlying principles ofspr sensor towards miniaturization, portability, and disposability features.
Journal ArticleDOI
Periodic Metallic Nanostructures as Plasmonic Chemical Sensors
TL;DR: The most common parameters used for the evaluation of plasmonic nanostructures will be reviewed, and a assessment of the state of the art in terms of periodic structures employed for chemical sensing is assessed.
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Nanoplasmonic sensors for biointerfacial science
TL;DR: The goal of this review is to introduce the latest advances in nanoplasmonic sensors for the biointerfacial sciences, including ongoing development of nanoparticle and nanohole arrays for exploring different classes of biomacromolecules interacting at solid-liquid interfaces.
Journal ArticleDOI
On-chip nanohole array based sensing: a review
Carlos Escobedo,Carlos Escobedo +1 more
TL;DR: The integration of nanohole array based plasmonic sensors into microfluidic systems has enabled the emergence of platforms with unique capabilities and a diversified palette of applications.
Journal ArticleDOI
Optofluidic Concentration: Plasmonic Nanostructure as Concentrator and Sensor
TL;DR: This work employs the nanohole array geometry and the conducting nature of the film to actively concentrate analyte within the sensor to achieve 180-fold enrichment of a dye, and 100-fold enriched and simultaneous sensing of a protein in less than 1 min.
References
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Extraordinary optical transmission through sub-wavelength hole arrays
Thomas W. Ebbesen,Thomas W. Ebbesen,Henri J. Lezec,H. F. Ghaemi,Tineke Thio,Peter A. Wolff,Peter A. Wolff +6 more
TL;DR: In this article, the optical properties of submicrometre cylindrical cavities in metallic films were explored and it was shown that arrays of such holes display highly unusual zero-order transmission spectra at wavelengths larger than the array period, beyond which no diffraction occurs.
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Rapid prototyping of microfluidic systems in poly(dimethylsiloxane)
TL;DR: A procedure that makes it possible to design and fabricate microfluidic systems in an elastomeric material poly(dimethylsiloxane) (PDMS) in less than 24 h by fabricating a miniaturized capillary electrophoresis system is described.
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Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
TL;DR: This work presents a meta-analysis of the literature on food quality and safety analysis and its applications in the context of veterinary drugs and drugs and drug-Induced Antibodies, which focuses on the role of canine coronavirus in the veterinary industry.
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Fabrication of microfluidic systems in poly(dimethylsiloxane)
J.C. McDonald,David C. Duffy,Janelle R. Anderson,Daniel T. Chiu,Hongkai Wu,Olivier Schueller,George M. Whitesides +6 more
TL;DR: Fabrication of microfluidic devices in poly(dimethylsiloxane) (PDMS) by soft lithography provides faster, less expensive routes to devices that handle aqueous solutions.
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Notizen: Radiative Decay of Non Radiative Surface Plasmons Excited by Light
E. Kretschmann,H. Raether +1 more
TL;DR: In this paper, it has been shown that the non-radiative mode excited by light can also radiate under certain conditions if they are excited by electrons (grazing incidence of electrons on a rough surface or at normal incidence on a grating).