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Journal ArticleDOI

Integration of polymer waveguides for optical detection in microfabricated chemical analysis systems.

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TLDR
Multimode polymer waveguides and fiber-to-waveguide couplers have been integrated with microfluidic channels by use of a single-mask-step procedure, which ensured self-alignment between the optics and the fluidics and allowed a fabrication and packaging time of only one day.
Abstract
Multimode polymer waveguides and fiber-to-waveguide couplers have been integrated with microfluidic channels by use of a single-mask-step procedure, which ensured self-alignment between the optics and the fluidics and allowed a fabrication and packaging time of only one day Three fabrication procedures for obtaining hermetically sealed channels were investigated, and the spectrally resolved propagation loss (400–900 nm) of the integrated waveguides was determined for all three procedures Two chemical absorbance cells with optical path lengths of 100 and 1000 μm were furthermore fabricated and characterized in terms of coupling loss, sensitivity, and limit of detection for measurements of the dye bromothymol blue

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Citations
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Journal ArticleDOI

Fabrication and measurement of optical waveguide sensor based on localized surface plasmon resonance

TL;DR: In this paper, a localized surface plasmon resonance (LSPR) sensor system based on polymer material is proposed, which consists of the incident medium with low-loss polymer waveguide and the chemically immobilized plasmoric nanoparticles for on-chip LSPR sensing.
Patent

Fluorescence-detected assays on microfluidic chips

TL;DR: In this article, a photonic system with two or more rectangular waveguide structures (62, 66, 63) arranged on the chip that are able to guide excitation light in the near IR, visible, or near UV range is described.
Proceedings ArticleDOI

A microfluidic-photonic-integrated device with enhanced excitation power density

TL;DR: In this article, the power density of optical excitation in microfluidic-photonic-integrated flow cytometers is typically provided from an integrated waveguide and the beam is therefore divergent within the microchannel due to the NA of the waveguide.
Proceedings ArticleDOI

A SU-8 microfluidic total analysis system integrating silicon photodiodes and buried waveguides

TL;DR: Blanco et al. as discussed by the authors described the monolithic integration of several optical structures that are needed for optical absorption or scattering measurements, including buried waveguides to confine light, a y-branch splitter to couple light to both photodiodes, a connector for input fibre coupling and a microfluidic circuit with an analytical chamber to allow propagation of light through the substance under analysis.
Journal ArticleDOI

Simple applications of microparticle transportation by tender optical scattering force

TL;DR: In this article, a novel application of the optical radiation pressure for microfluidic particle transportation without precise focusing or alignment of the laser beam to the device and target is presented.
References
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Journal ArticleDOI

Micro Total Analysis Systems. 1. Introduction, Theory, and Technology

TL;DR: In this article, the authors present a review of the book.http://www.reviewreviews.com/reviews/book-reviews-of-the-book
Journal ArticleDOI

Micro total analysis systems. 2. Analytical standard operations and applications.

TL;DR: This second part of the review of microfluidic system preparation will cover a number of standard operations as well as some biological applications of micro total analysis systems.
Journal ArticleDOI

Advances in polymer integrated optics

TL;DR: In this paper, the authors report on advances in polymeric waveguide technologies developed worldwide for the telecom and datacom markets, and describe in detail one such technology developed at AlliedSignal.
Journal ArticleDOI

Microfluidic chips for clinical and forensic analysis

TL;DR: Few cases of microchip analysis of physiological samples or other “real‐world” matrices were found, but many of the examples presented have potential application for these samples, especially with ongoing parallel developments involving integration of sample pretreatment onto chips and the use of fluid propulsion mechanisms other than electrokinetic pumping.
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