Journal ArticleDOI
Interaction of coumarin with calf thymus DNA: Deciphering the mode of binding by in vitro studies
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TLDR
Analysis of UV-visible absorbance spectra and fluorescence spectra indicates the formation of complex between coumarin and Ct-DNA, and observation of effect of ionic strength, iodide induced quenching, and competitive binding assay with ethidium bromide, acridine orange and Hoechst 33258 reflected that cou marin possibly binds to the minor groove of the Ct- DNA.About:
This article is published in International Journal of Biological Macromolecules.The article was published on 2015-02-01. It has received 135 citations till now. The article focuses on the topics: Ethidium bromide & Docking (molecular).read more
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Studying non-covalent drug-DNA interactions.
TL;DR: This review focuses on discussing various techniques used to study non-covalent interactions that occur between drugs and DNA and reports several techniques that may be employed to analyse the binding mode of a drug with DNA.
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Multi-spectroscopic and molecular modelling studies on the interaction of esculetin with calf thymus DNA.
TL;DR: The strong dependence on ionic strength in controlling the binding of esculetin with Ct-DNA confirms the possibility of electrostatic interaction.
Journal ArticleDOI
Production of green surfactants: Market prospects
Charles Bronzo B. Farias,Charles Bronzo B. Farias,Charles Bronzo B. Farias,Fabíola Carolina G. Almeida,Fabíola Carolina G. Almeida,Ivison A. Silva,Ivison A. Silva,Ivison A. Silva,Thais C. Souza,Hugo M. Meira,Hugo M. Meira,Rita de Cássia Freire Soares da Silva,Rita de Cássia Freire Soares da Silva,J.M. Luna,J.M. Luna,Valdemir Alexandre dos Santos,Valdemir Alexandre dos Santos,Attilio Converti,Attilio Converti,Ibrahim M. Banat,Ibrahim M. Banat,Leonie Asfora Sarubbo,Leonie Asfora Sarubbo,Leonie Asfora Sarubbo +23 more
TL;DR: A review of green surfactants can be found in this article, where the authors discuss the different types, properties, and uses of surfactant components with a focus on green detergents, and describe the current scenario as well as the projections for the future market economy related to the production of different types of green suractants.
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Multi-spectroscopic and molecular modeling studies to reveal the interaction between propyl acridone and calf thymus DNA in the presence of histone H1: binary and ternary approaches.
TL;DR: Experimental results proved that the intercalative binding between PA and ct DNA as well as the (H1-ct DNA) complex as binary and ternary systems must be predominant.
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Deciphering the interactions between chlorambucil and calf thymus DNA: a multi-spectroscopic and molecular docking study.
Sayeed Ur Rehman,Tarique Sarwar,Hassan Mubarak Ishqi,Mohammed Amir Husain,Ziaul Hasan,Mohammad Tabish +5 more
TL;DR: Chlorambucil was found to interact via external binding mode and follow groove binding as it replaces Hoechst (a typical groove binder) from the groove of DNA but does not replace intercalating dyes including ethidium bromide and acridine orange from the DNA helix.
References
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The Protein Data Bank
Helen M. Berman,John D. Westbrook,Zukang Feng,Gary L. Gilliland,Talapady N. Bhat,Helge Weissig,Ilya N. Shindyalov,Philip E. Bourne +7 more
TL;DR: The goals of the PDB are described, the systems in place for data deposition and access, how to obtain further information and plans for the future development of the resource are described.
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Quenching of fluorescence by oxygen. A probe for structural fluctuations in macromolecules.
TL;DR: In this article, the fluorescence of various fluorophores by molecular oxygen has been studied in aqueous and nonaqueous solutions equilibrated with oxygen pressures up to 100 atm.
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Structural considerations in the interaction of DNA and acridines.
L.S. Lerman,L.S. Lerman +1 more
TL;DR: The proposed structural change is compatible with the normal restrictions on bond lengths, angles, and non-bonded contacts, and maintenance of the hydrogen- bonded base pairs perpendicular to the axis of the molecule.
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Recognition and reaction of metallointercalators with DNA.
TL;DR: A more complete understanding of how to target DNA sites with specificity will lead not only to novel chemotherapeutics but also to a greatly expanded ability for chemists to probe DNA and to develop highly sensitive diagnostic agents.