Interpretative strategies for lung function tests
Riccardo Pellegrino,Giovanni Viegi,Vito Brusasco,Robert O. Crapo,Felip Burgos,Richard Casaburi,Allan L. Coates,C.P.M. van der Grinten,P. Gustafsson,John L. Hankinson,R. Jensen,D.C. Johnson,Neil R. MacIntyre,Roy T. McKay,Martin R. Miller,Daniel Navajas,O. F. Pedersen,J. Wanger +17 more
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This section is written to provide guidance in interpreting pulmonary function tests (PFTs) to medical directors of hospital-based laboratories that perform PFTs, and physicians who are responsible for interpreting the results of PFTS most commonly ordered for clinical purposes.Abstract:
SERIES “ATS/ERS TASK FORCE: STANDARDISATION OF LUNG FUNCTION TESTING”
Edited by V. Brusasco, R. Crapo and G. Viegi
Number 5 in this Series
This section is written to provide guidance in interpreting pulmonary function tests (PFTs) to medical directors of hospital-based laboratories that perform PFTs, and physicians who are responsible for interpreting the results of PFTs most commonly ordered for clinical purposes. Specifically, this section addresses the interpretation of spirometry, bronchodilator response, carbon monoxide diffusing capacity ( D L,CO) and lung volumes.
The sources of variation in lung function testing and technical aspects of spirometry, lung volume measurements and D L,CO measurement have been considered in other documents published in this series of Task Force reports 1–4 and in the American Thoracic Society (ATS) interpretative strategies document 5.
An interpretation begins with a review and comment on test quality. Tests that are less than optimal may still contain useful information, but interpreters should identify the problems and the direction and magnitude of the potential errors. Omitting the quality review and relying only on numerical results for clinical decision making is a common mistake, which is more easily made by those who are dependent upon computer interpretations.
Once quality has been assured, the next steps involve a series of comparisons 6 that include comparisons of test results with reference values based on healthy subjects 5, comparisons with known disease or abnormal physiological patterns ( i.e. obstruction and restriction), and comparisons with self, a rather formal term for evaluating change in an individual patient. A final step in the lung function report is to answer the clinical question that prompted the test.
Poor choices made during these preparatory steps increase the risk of misclassification, i.e. a falsely negative or falsely positive interpretation for a lung function abnormality or a change …read more
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TL;DR: A proportion of children with STRA exhibit increased intraepithelial airway neutrophilia that correlated with better lung function, and a potential beneficial rather than adverse role for neutrophils in pediatric severe asthma pathophysiology is suggested.
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Reduced lung function due to biomass smoke exposure in young adults in rural Nepal
Om P Kurmi,Graham Devereux,W. Cairns S. Smith,Sean Semple,Markus F C Steiner,Padam Simkhada,Kin Bong Hubert Lam,Jon G Ayres +7 more
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Jamilah Meghji,Maia Lesosky,Elizabeth Joekes,Peter K Banda,Jamie Rylance,Stephen B. Gordon,Joseph Jacob,H. M. Zonderland,Peter MacPherson,Elizabeth L. Corbett,Kevin Mortimer,Stephen Bertel Squire +11 more
TL;DR: PTLD is a common and under-recognised consequence of pTB that is disabling for patients and associated with adverse outcomes beyond pTB treatment completion, and low-cost clinical interventions to improve patient outcomes must be evaluated.
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Multivariate analysis of risk factors for pulmonary complications after hepatic resection.
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TL;DR: The correction of modifiable risk factors among the identified factors could reduce the incidence of PPCs and, as a consequence, improve patient outcomes and reduce the length of hospital stays.
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6-Minute walk distance in healthy North Africans older than 40 years: Influence of parity
Helmi Ben Saad,Christian Préfaut,Zouhair Tabka,Abdelaziz Hadj Mtir,Mohamed Chemit,Rym Hassaoune,Tarek Ben Abid,Khelifa Zara,Gregoire Mercier,Abdelkrim Zbidi,Maurice Hayot +10 more
TL;DR: This reliable 6-MWD reference equation for healthy North African adults older than 40 years was assessed and provides an important element of interpretation for women with high parity and enriches the World Bank.
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Standardisation of spirometry
Martin R. Miller,John L. Hankinson,Vito Brusasco,Felip Burgos,Richard Casaburi,Allan L. Coates,Robert O. Crapo,Paul L. Enright,C.P.M. van der Grinten,P. Gustafsson,R. Jensen,D.C. Johnson,Neil R. MacIntyre,Roy T. McKay,Daniel Navajas,O. F. Pedersen,Riccardo Pellegrino,Giovanni Viegi,J. Wanger +18 more
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Standardisation of spirometry
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