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Journal ArticleDOI

Invasive aspergillosis in allogeneic stem cell transplant recipients: changes in epidemiology and risk factors

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TLDR
Risk factor analyses verify previously recognized risk factors (GVHD, receipt of corticosteroids, and neutropenia) and uncover the roles of lymphopenia and viral infections in increasing the incidence of postengraftment IA in the 1990s.
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This article is published in Blood.The article was published on 2002-12-15. It has received 906 citations till now. The article focuses on the topics: Hematopoietic stem cell transplantation & Graft-versus-host disease.

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Citations
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Graft-versus-host disease

TL;DR: The understanding of the risk factors and causes of GHVD, the cellular and cytokine networks implicated in its pathophysiology, and current strategies to prevent and treat the disease are reviewed.
Journal ArticleDOI

Immunity to fungal infections

TL;DR: Research in this field is entering an exciting period of transition from studying the molecular and cellular bases of fungal virulence to determining the cellular and molecular mechanisms that maintain immune homeostasis with fungi.
Journal ArticleDOI

Global and Multi-National Prevalence of Fungal Diseases—Estimate Precision

TL;DR: The accuracy of the estimation of the burden of serious fungal infections country by country for over 5.7 billion people is questioned in the 43 published papers within the LIFE initiative.
References
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Book ChapterDOI

Nonparametric Estimation from Incomplete Observations

TL;DR: In this article, the product-limit (PL) estimator was proposed to estimate the proportion of items in the population whose lifetimes would exceed t (in the absence of such losses), without making any assumption about the form of the function P(t).
Journal Article

1994 Consensus Conference on Acute GVHD Grading.

TL;DR: Reports of GVHD prevention trials should include an accurate description of the grading system used and should report actuarial rates of grades II-IV and III-IV GV HD corrected for graft failure and potential interventions for early relapse.
Journal ArticleDOI

Aspergillus fumigatus and Aspergillosis

TL;DR: This review focuses on the biology of A. fumigatus, one of the most ubiquitous of the airborne saprophytic fungi, and the diseases it causes, and discusses discussions of genomic and molecular characterization of the organism.

Aspergillus fumigatus and aspergillosis.

TL;DR: A review of the biology of Aspergillus fumigatus and the diseases it causes can be found in this article, where the authors discuss genomic and molecular characterization of the organism, clinical and laboratory methods available for the diagnosis of aspergillosis in immunocompetent and immunOCompromised hosts, identification of host and fungal factors that play a role in the establishment of the fungus in vivo, and problems associated with antifungal therapy.
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Trending Questions (1)
What complications of Aspergillosis will occur by Graft-versus-host disease?

Graft-versus-host disease is a risk factor for postengraftment invasive aspergillosis.