Is there a general factor of prevalent psychopathology during adulthood
Benjamin B. Lahey,Brooks Applegate,Jahn K. Hakes,David H. Zald,Ahmad R. Hariri,Paul J. Rathouz +5 more
TLDR
The hypothesis that these prevalent forms of psychopathology have both important common and unique features is supported, which is whether this is because they share elements of their etiology and neurobiological mechanisms.Abstract:
The patterns of comorbidity among prevalent mental disorders in adults lead them to load on “externalizing,” “distress,” and “fears” factors. These factors are themselves robustly correlated, but little attention has been paid to this fact. As a first step in studying the implications of these interfactor correlations, we conducted confirmatory factor analyses on diagnoses of 11 prevalent Diagnostic and Statistical Manual of Mental Disorders (4th ed.) mental disorders in a nationally representative sample. A model specifying correlated externalizing, distress, and fears factors fit well, but an alternative model was tested in which a “general” bifactor was added to capture what these disorders share in common. There was a modest but significant improvement in fit for the bifactor model relative to the 3-factor oblique model, with all disorders loading strongly on the bifactor. Tests of external validity revealed that the fears, distress, and externalizing factors were differentially associated with measures of functioning and potential risk factors. Nonetheless, the general bifactor accounted for significant independent variance in future psychopathology, functioning, and other criteria over and above the fears, distress, and externalizing factors. These findings support the hypothesis that these prevalent forms of psychopathology have both important common and unique features. Future studies should determine whether this is because they share elements of their etiology and neurobiological mechanisms. If so, the existence of common features across diverse forms of prevalent psychopathology could have important implications for understanding the nature, etiology, and outcomes of psychopathology.read more
Citations
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The p Factor: One General Psychopathology Factor in the Structure of Psychiatric Disorders?
Avshalom Caspi,Renate Houts,Daniel W. Belsky,Sidra Goldman-Mellor,HonaLee Harrington,Salomon Israel,Madeline H. Meier,Sandhya Ramrakha,Idan Shalev,Richie Poulton,Terrie E. Moffitt +10 more
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The Hierarchical Taxonomy of Psychopathology (HiTOP): A Dimensional Alternative to Traditional Nosologies
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Advancing understanding of executive function impairments and psychopathology: bridging the gap between clinical and cognitive approaches.
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References
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Book
Methodology for Genetic Studies of Twins and Families
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Bridget F. Grant,Deborah A. Dawson,Frederick S. Stinson,S. Patricia Chou,Mary C. Dufour,Roger P. Pickering +5 more
TL;DR: In this paper, the authors present nationally representative data on the prevalence of 12-month DSM-IV alcohol abuse and dependence in 2001-2002 and examine trends in alcohol abuse between 1991-1992 and 2001- 2002.
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Methodology for Genetic Studies of Twins and Families
TL;DR: The saimie paper suggests how susceptible individuals could reduce their total intake of aluminium and suggests that although definite proof is still lacking, there is more than enough evidence to fuel further epidemiological investigation.
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