Laboratory Diagnosis for SARS-CoV-2 Infection
TLDR
The optimal diagnostic test for SARS-CoV-2 infection should be selected based on a patient's clinical syndrome and presentation in relation to symptom onset as mentioned in this paper , and the optimal test should be chosen based on the patient's symptoms and presentation.About:
This article is published in Infectious Disease Clinics of North America.The article was published on 2022-05-27 and is currently open access. It has received 4 citations till now. The article focuses on the topics: Medicine & Medicine.read more
Citations
More filters
Journal ArticleDOI
Expert consensus on the diagnosis and treatment of severe and critical coronavirus disease 2019
Y Shang,Jian-Feng Wu,Jing-long Liu,Yun Long,Jianfeng Xie,Dong Ye Zhang,B.‐L. Hu,Yuan Zong,Xuelian Liao,Xiuling Shang,Renyu Ding,Kai Kang,Jiaozhi Liu,Aijun Pan,Yonghao Xiu,Changsong Wang,Qianghong Xu,Xijing Zhang,Jicheng Zhang,Lin Liu,Jiancheng Zhang,Yi Yang,Kai Yu,Xiangdong Guan,Dechang Chen +24 more
TL;DR: A group of critical care medicine experts across China were organized to formulate this consensus based on a literature review, the clinical experience gained in the fight with the pandemic in China, and several expert workshops to guide clinical practice.
Journal ArticleDOI
Expert consensus on the diagnosis and treatment of severe and critical coronavirus disease 2019 (COVID-19)
You Shang,Jian-Feng Wu,Jing-long Liu,Yun Long,Jianfeng Xie,Dong Ye Zhang,Bo Hu,Yuan Zong,Xuelian Liao,Xiuling Shang,Renyu Ding,Kai Kang,Jiaozhi Liu,Aijun Pan,Yonghao Xiu,Changsong Wang,Qianghong Xu,Xijing Zhang,Jicheng Zhang,Lin Liu,Jiancheng Zhang,Yi Yang,Kai Yu,Xiangdong Guan,Dechang Chen +24 more
Journal ArticleDOI
Distinct Molecular Mechanisms Characterizing Pathogenesis of SARS-CoV-2
TL;DR: The molecular mechanisms of SARS-CoV-2 propagation and pathogenesis are discussed, with an update on recent advances.
Journal ArticleDOI
Systematic analysis on expression quantitative trait loci identifies a novel regulatory variant in ring finger and WD repeat domain 3 associated with prognosis of pancreatic cancer
Ying Zhu,Xiating Peng,Xiaoyang Wang,Pingting Ying,Haoxue Wang,Bin Li,Yue Li,Ping Zhang,Yimin Cai,Zequn Lu,Siyuan Niu,Nan Yang,Rong Zhong,Jianbo Tian,Jiang Chang,Xiaoping Miao +15 more
TL;DR: RFWD3 and its regulatory variant are novel genetic factors for PAAD prognosis and might orchestrate the genes in the DNA repair process.
References
More filters
Journal ArticleDOI
Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding.
Roujian Lu,Xiang Zhao,Juan Li,Peihua Niu,Bo Yang,Honglong Wu,Wenling Wang,Hao Song,Baoying Huang,Na Zhu,Yuhai Bi,Xuejun Ma,Faxian Zhan,Liang Wang,Tao Hu,Hong Zhou,Zhenhong Hu,Weimin Zhou,Li Zhao,Jing Chen,Yao Meng,Ji Wang,Yang Lin,Jianying Yuan,Zhihao Xie,Jinmin Ma,William J. Liu,Dayan Wang,Wenbo Xu,Edward C. Holmes,George F. Gao,George F. Gao,Guizhen Wu,Weijun Chen,Weifeng Shi,Wenjie Tan,Wenjie Tan +36 more
TL;DR: The phylogenetic analysis suggests that bats might be the original host of this virus, an animal sold at the seafood market in Wuhan might represent an intermediate host facilitating the emergence of the virus in humans.
Journal ArticleDOI
SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients.
Lirong Zou,Feng Ruan,Mingxing Huang,Lijun Liang,Huitao Huang,Zhongsi Hong,Jianxiang Yu,Min Kang,Yingchao Song,Jinyu Xia,Qianfang Guo,Tie Song,Jianfeng He,Hui-Ling Yen,Malik Peiris,Jie Wu +15 more
TL;DR: Results of an analysis of nasal and throat swabs from 17 patients in Zhuhai, China, who had received a diagnosis of Covid-19 and found SARS-CoV-2 Viral Load in Upper Respiratory Specimens positive.
Journal ArticleDOI
Temporal dynamics in viral shedding and transmissibility of COVID-19.
Xi He,Eric H. Y. Lau,Peng Wu,Xilong Deng,Jian Wang,Xinxin Hao,Yiu Chung Lau,Jessica Y. Wong,Yujuan Guan,Xinghua Tan,Xiaoneng Mo,Yanqing Chen,Baolin Liao,Weilie Chen,Fengyu Hu,Qing Zhang,Mingqiu Zhong,Yanrong Wu,Lingzhai Zhao,Fuchun Zhang,Benjamin J. Cowling,Fang Li,Gabriel M. Leung +22 more
TL;DR: It is estimated that 44% (95% confidence interval, 25–69%) of secondary cases were infected during the index cases’ presymptomatic stage, in settings with substantial household clustering, active case finding and quarantine outside the home.
Journal ArticleDOI
Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study.
Kelvin K. W. To,Owen Tak Yin Tsang,Wai Shing Leung,Anthony Raymond Tam,Tak Chiu Wu,David Christopher Lung,Cyril C. Y. Yip,Jian Piao Cai,Jacky Man Chun Chan,Thomas Shiu Hong Chik,Daphne Pui-Ling Lau,Chris Yau Chung Choi,Lin Lei Chen,Wan Mui Chan,Kwok-Hung Chan,Jonathan Daniel Ip,Anthony Chin-Ki Ng,Rosana W.S. Poon,Cui Ting Luo,Vincent C.C. Cheng,Jasper Fuk-Woo Chan,Jasper Fuk-Woo Chan,Ivan Hung,Zhiwei Chen,Honglin Chen,Kwok-Yung Yuen +25 more
TL;DR: The serial respiratory viral load of SARS-CoV-2 in posterior oropharyngeal saliva samples from patients with COVID-19, and serum antibody responses from patients infected with severe acute respiratory syndrome coronavirus 2 are ascertained.
Journal ArticleDOI
Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection.
David S. Khoury,Deborah Cromer,Arnold Reynaldi,Timothy E. Schlub,Timothy E. Schlub,Adam K. Wheatley,Jennifer A Juno,Kanta Subbarao,Stephen J. Kent,Stephen J. Kent,Stephen J. Kent,James A. Triccas,Miles P. Davenport +12 more
TL;DR: It is shown that neutralization level is highly predictive of immune protection, and an evidence-based model of SARS-CoV-2 immune protection that will assist in developing vaccine strategies to control the future trajectory of the pandemic is provided.