Journal ArticleDOI
Loss of skeletal muscle mass in aging: examining the relationship of starvation, sarcopenia and cachexia.
Reads0
Chats0
TLDR
The key clinical question is whether changes in body composition are distinct entities or represent an interdependent continuum and the importance of defining the distinction lies in developing a targeted therapeutic approach to skeletal muscle loss and muscle strength in older persons.About:
This article is published in Clinical Nutrition.The article was published on 2007-08-01. It has received 466 citations till now. The article focuses on the topics: Sarcopenia & Cachexia.read more
Citations
More filters
Journal ArticleDOI
Sarcopenia: European consensus on definition and diagnosis Report of the European Working Group on Sarcopenia in Older People
Alfonso J. Cruz-Jentoft,Jean-Pierre Baeyens,Jürgen M. Bauer,Yves Boirie,Tommy Cederholm,Francesco Landi,Finbarr C. Martin,Jean-Pierre Michel,Yves Rolland,Stéphane M. Schneider,Eva Topinkova,Maurits Vandewoude,Mauro Zamboni +12 more
TL;DR: The European Working Group on Sarcopenia in Older People (EWGSOP) developed a practical clinical definition and consensus diagnostic criteria for age-related sarcopenia as discussed by the authors.
Journal ArticleDOI
Consensus definition of sarcopenia, cachexia and pre-cachexia: joint document elaborated by Special Interest Groups (SIG) "cachexia-anorexia in chronic wasting diseases" and "nutrition in geriatrics"
Maurizio Muscaritoli,Stefan D. Anker,Josep M. Argilés,Zaira Aversa,Juergen M. Bauer,Gianni Biolo,Yves Boirie,Ingvar Bosaeus,Tommy Cederholm,Paola Costelli,Kenneth C. H. Fearon,Alessandro Laviano,Marcello Maggio,F. Rossi Fanelli,Stéphane M. Schneider,Annemie M. W. J. Schols,Cornel C. Sieber +16 more
TL;DR: The definition of cachexia, pre-cachexia and sarc Openia as well as the criteria for the differentiation between cachexia and other conditions associated with sarcopenia, which have been developed in cooperation with the ESPEN SIG on nutrition in geriatrics are reported.
Journal ArticleDOI
Protein intake and exercise for optimal muscle function with aging: recommendations from the ESPEN Expert Group
Nicolaas E. P. Deutz,Jürgen M. Bauer,Rocco Barazzoni,Gianni Biolo,Yves Boirie,Anja Bosy-Westphal,Tommy Cederholm,Tommy Cederholm,Alfonso J. Cruz-Jentoft,Zeljko Krznaric,K. Sreekumaran Nair,Pierre Singer,Daniel Teta,Kevin D. Tipton,Philip C. Calder,Philip C. Calder +15 more
TL;DR: Recommendations are made that daily physical activity or exercise (resistance training, aerobic exercise) should be undertaken by all older people, for as long as possible to help older adults sustain muscle strength and function into older age.
Journal ArticleDOI
The role of exercise and PGC1α in inflammation and chronic disease
TL;DR: It is proposed that the transcriptional coactivator PGC1α controls muscle plasticity, suppresses a broad inflammatory response and mediates the beneficial effects of exercise.
Journal ArticleDOI
Sarcopenia, Dynapenia, and the Impact of Advancing Age on Human Skeletal Muscle Size and Strength; a Quantitative Review
TL;DR: The aim of this review is to present current knowledge of the decline in human muscle mass and strength with advancing age and the associated risk to health and survival and to review the underlying changes in muscle characteristics and the etiology of sarcopenia.
References
More filters
Journal ArticleDOI
Body-Mass Index and Mortality in a Prospective Cohort of U.S. Adults
TL;DR: The risk of death from all causes, cardiovascular disease, cancer, or other diseases increases throughout the range of moderate and severe overweight for both men and women in all age groups.
Journal ArticleDOI
Epidemiology of Sarcopenia among the Elderly in New Mexico
Richard N. Baumgartner,Kathleen M. Koehler,Dympna Gallagher,Linda J. Romero,Steven B. Heymsfield,Robert Ross,Philip J. Garry,Robert D. Lindeman +7 more
TL;DR: Some of the first estimates of the extent of the public health problem posed by sarcopenia are provided, independent of ethnicity, age, morbidity, obesity, income, and health behaviors.
Journal ArticleDOI
Exercise training and nutritional supplementation for physical frailty in very elderly people
Maria A. Fiatarone,Evelyn F. O'Neill,Nancy D. Ryan,Karen M. Clements,Guido R. Solares,Miriam E. Nelson,Susan B. Roberts,Joseph J. Kehayias,Lewis A. Lipsitz,William J. Evans +9 more
TL;DR: High-intensity resistance exercise training is a feasible and effective means of counteracting muscle weakness and physical frailty in very elderly people, in contrast to multi-nutrient supplementation without concomitant exercise, which does not reduce muscle weakness orPhysical frailty.
Journal ArticleDOI
What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old men
TL;DR: The results show that the ageing atrophy of this muscle begins around 25 years of age and thereafter accelerates, and suggest the occurrence of several other age-related adaptive mechanisms which could influence fiber sizes and fiber number, as well as enzyme histochemical fiber characteristics.
Journal ArticleDOI
Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?
TL;DR: A role for IL-6 is proposed in the pathogenesis of CHD through a combination of autocrine, paracrine and endocrine mechanisms, activation of which is associated with central obesity, hypertension and insulin resistance.
Related Papers (5)
Cachexia: a new definition.
William J. Evans,John E. Morley,Josep M. Argilés,Connie W. Bales,Vickie E. Baracos,Denis Guttridge,Aminah Jatoi,Kamyar Kalantar-Zadeh,H. Lochs,Giovanni Mantovani,Daniel L. Marks,William E. Mitch,Maurizio Muscaritoli,Armine Najand,Piotr Ponikowski,Filippo Rossi Fanelli,Morrie Schambelan,Annemie M. W. J. Schols,Michael W. Schuster,David R. Thomas,Robert R. Wolfe,Stefan D. Anker +21 more