Measuring the thickness of the human cerebral cortex from magnetic resonance images
Bruce Fischl,Anders M. Dale +1 more
Reads0
Chats0
TLDR
An automated method for accurately measuring the thickness of the cerebral cortex across the entire brain and for generating cross-subject statistics in a coordinate system based on cortical anatomy is presented.Abstract:
Accurate and automated methods for measuring the thickness of human cerebral cortex could provide powerful tools for diagnosing and studying a variety of neurodegenerative and psychiatric disorders. Manual methods for estimating cortical thickness from neuroimaging data are labor intensive, requiring several days of effort by a trained anatomist. Furthermore, the highly folded nature of the cortex is problematic for manual techniques, frequently resulting in measurement errors in regions in which the cortical surface is not perpendicular to any of the cardinal axes. As a consequence, it has been impractical to obtain accurate thickness estimates for the entire cortex in individual subjects, or group statistics for patient or control populations. Here, we present an automated method for accurately measuring the thickness of the cerebral cortex across the entire brain and for generating cross-subject statistics in a coordinate system based on cortical anatomy. The intersubject standard deviation of the thickness measures is shown to be less than 0.5 mm, implying the ability to detect focal atrophy in small populations or even individual subjects. The reliability and accuracy of this new method are assessed by within-subject test-retest studies, as well as by comparison of cross-subject regional thickness measures with published values.read more
Citations
More filters
Journal ArticleDOI
Default mode network links to visual hallucinations: A comparison between Parkinson's disease and multiple system atrophy
Raffaella Franciotti,Stefano Delli Pizzi,Bernardo Perfetti,Armando Tartaro,Laura Bonanni,Astrid Thomas,Luca Weis,Roberta Biundo,Angelo Antonini,Marco Onofrj +9 more
TL;DR: This work aimed to evaluate default mode network functions in multiple system atrophy in comparison with Parkinson's disease.
Journal ArticleDOI
Cortical asymmetry in Parkinson's disease: early susceptibility of the left hemisphere.
Daniel O. Claassen,Katherine E McDonell,Manus J. Donahue,Shiv Rawal,Scott A. Wylie,Joseph S. Neimat,Hakmook Kang,Peter Hedera,David H. Zald,Bennett A. Landman,Benoit M. Dawant,Swati Rane +11 more
TL;DR: Evaluating hemispheric differences in estimated rates of atrophy in a large, well‐characterized cohort of PD patients found that the left nigrostriatal system appears more susceptible to early degeneration than the right.
Journal ArticleDOI
Development of cortical anatomical properties from early childhood to early adulthood.
TL;DR: The result shows that the development of cortex reaches a turning point at around 7 years of age, where the cortical thickness reaches its highest value and also the cortical folding becomes stable at this age.
Journal ArticleDOI
Hemispheric asymmetries of cortical volume in the human brain
Elkhonon Goldberg,Donovan Roediger,N. Erkut Kucukboyaci,N. Erkut Kucukboyaci,Chad Carlson,Orrin Devinsky,Ruben Kuzniecky,Eric Halgren,Thomas Thesen +8 more
TL;DR: Hemispheric asymmetry represents a cardinal feature of cerebral organization, but the nature of structural and functional differences between the hemispheres is far from fully understood.
Journal ArticleDOI
Socioeconomic Status and Reading Disability: Neuroanatomy and Plasticity in Response to Intervention.
Rachel R. Romeo,Rachel R. Romeo,Joanna A. Christodoulou,Joanna A. Christodoulou,Joanna A. Christodoulou,Kelly Halverson,Jack Murtagh,Abigail Cyr,Carly Schimmel,Patricia Chang,Pamela E. Hook,John D. E. Gabrieli,John D. E. Gabrieli,John D. E. Gabrieli +13 more
TL;DR: It is indicated that effective summer reading intervention is coupled with cortical growth, and is especially beneficial for children with RD who come from lower-SES home environments.
References
More filters
Numerical recipes in C
TL;DR: The Diskette v 2.06, 3.5''[1.44M] for IBM PC, PS/2 and compatibles [DOS] Reference Record created on 2004-09-07, modified on 2016-08-08.
Journal ArticleDOI
Snakes : Active Contour Models
TL;DR: This work uses snakes for interactive interpretation, in which user-imposed constraint forces guide the snake near features of interest, and uses scale-space continuation to enlarge the capture region surrounding a feature.
Journal ArticleDOI
Cortical surface-based analysis. I. Segmentation and surface reconstruction
TL;DR: A set of automated procedures for obtaining accurate reconstructions of the cortical surface are described, which have been applied to data from more than 100 subjects, requiring little or no manual intervention.
Book
Co-planar stereotaxic atlas of the human brain : 3-dimensional proportional system : an approach to cerebral imaging
TL;DR: Direct and Indirect Radiologic Localization Reference System: Basal Brain Line CA-CP Cerebral Structures in Three-Dimensional Space Practical Examples for the Use of the Atlas in Neuroradiologic Examinations Three- Dimensional Atlas of a Human Brain Nomenclature-Abbreviations Anatomic Index Conclusions.