Journal ArticleDOI
Metal contamination, bioaccumulation, ROS generation, and epigenotoxicity influences on zebrafish exposed to river water polluted by mining activities
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TLDR
Zebrafish was used as a biological model to study pollution of Le'an River, and it was shown that midstream and downstream sections of the river were seriously polluted by trace metals.About:
This article is published in Journal of Hazardous Materials.The article was published on 2021-03-05. It has received 25 citations till now. The article focuses on the topics: Trace metal & Bioaccumulation.read more
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Inflammatory, Oxidative Stress, and Apoptosis Effects in Zebrafish Larvae after Rapid Exposure to a Commercial Glyphosate Formulation
TL;DR: In this paper, the effects of acute exposure to a commercial formulation of glyphosate, Roundup® Flex (RF), at environmentally relevant and higher concentrations in zebrafish larvae through the assessment of the inflammatory, oxidative stress and cell death response were evaluated.
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Biomarker for monitoring heavy metal pollution in aquatic environment: An overview toward molecular perspectives
TL;DR: In this paper , a review of studies using biomarkers for monitoring heavy metal pollution in rivers is presented, which is expected to reference and encourage future biomarker research, especially for measuring heavy metal contamination in rivers.
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Effects of polycyclic aromatic hydrocarbons and multiple metals co-exposure on the mosaic loss of chromosome Y in peripheral blood.
Yansen Bai,Xin Guan,Wei Wei,Yue Feng,Hua Meng,Guyanan Li,Hang Li,Mengying Li,Chenming Wang,Ming Fu,Jiali Jie,Xiaomin Zhang,Meian He,Huan Guo +13 more
TL;DR: In this paper, the internal exposure levels of 11 polycyclic aromatic hydrocarbon (PAH) metabolites and 22 metals among 888 coke-oven workers were detected and calculated based on genome-wide SNP genotyping data and presented as median log R ratio (mLRR-Y).
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Acute effects of antimony exposure on adult zebrafish (Danio rerio): From an oxidative stress and intestinal microbiota perspective.
TL;DR: In this article , the acute toxic effects of various concentrations of antimony on adult zebrafish (Danio rerio) were investigated, including effects on oxidative stress, neurotransmitters and intestinal microbiota.
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Hydrogen-Rich Water Alleviates the Nickel-Induced Toxic Responses (Inflammatory Responses, Oxidative Stress, DNA Damage) and Ameliorates Cocoon Production in Earthworm.
TL;DR: In this article, the effects of hydrogen-rich water on different nickel-induced toxic responses (reactive oxygen species (ROS), tumor necrosis factor-alpha (TNF-α), and 8-hydroxy-2′-deoxyguanosine (8-OHdG) of stress responses, histopathological changes) and cocoon production in earthworm model were assessed.
References
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ROS signalling in the biology of cancer.
TL;DR: The generation and sources of ROS within tumour cells, the regulation of ROS by antioxidant defence systems, as well as the effect of elevated ROS production on their signalling targets in cancer are discussed.
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Global evaluation of heavy metal content in surface water bodies: A meta-analysis using heavy metal pollution indices and multivariate statistical analyses
Vinod Kumar,Ripu Daman Parihar,Anket Sharma,Palak Bakshi,Gagan Preet Singh Sidhu,Aditi Shreeya Bali,Ioannis Karaouzas,Renu Bhardwaj,Ashwani Kumar Thukral,Yeboah Gyasi-Agyei,Jesús Rodrigo-Comino +10 more
TL;DR: Results of ingestion and dermal pathways for adults and children in the current analyzed review showed that As is the major contaminant, and remediation techniques such as the introduction of aquatic phytoremediation plant species and adsorbents should be included in land management plans in order to reduce human risks.
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An Overview of Carcinogenic Heavy Metal: Molecular Toxicity Mechanism and Prevention.
TL;DR: The analyzed data showed that Arsenic, cadmium, chromium, and nickel induce oxidative stress, DNA damage, and cell death processes, resulting in increase the risk of cancer and cancer-related diseases.
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Anthropogenic pollution of aquatic ecosystems: Emerging problems with global implications
Donat-P. Häder,Anastazia T. Banaszak,Virginia E. Villafañe,Virginia E. Villafañe,Maite Andrea Narvarte,Maite Andrea Narvarte,Raúl González,Raúl González,E. Walter Helbling,E. Walter Helbling +9 more
TL;DR: Five sources of anthropogenic pollution that affect marine and freshwater ecosystems are discussed: sewage, nutrients and terrigenous materials, crude oil, heavy metals and plastics, and the direct and indirect effects that these pollutants have on a range of aquatic organisms even when the pollutant source is distant from the sink.
Journal ArticleDOI
Associating cellular epigenetic models with human phenotypes
TL;DR: Refocused, epigenetics research aligns with the field of functional genomics to provide insights into environmental and genetic influences on phenotypic variation in humans.