Journal ArticleDOI
Molecular and cellular adaptation of muscle in response to exercise: perspectives of various models
TLDR
Article de synthese sur l'adaptation cellulaire (assimilation du glucose), moleculaire (flux d'oxygene; enzymes glycolytiques) des muscles squelettiques en reponse a un exercice (aerobique, exercice de resistance).Abstract:
Article de synthese sur l'adaptation cellulaire (assimilation du glucose) et moleculaire (flux d'oxygene; enzymes glycolytiques) des muscles squelettiques en reponse a un exercice (aerobique, exercice de resistance). Utilisation de plusieurs modeles animaux (vertebres), de cultures cellulaires et comparaison avec l'activite physique humaine. Synthese sur les adaptations affectant le flux cardiaque, le flux sanguin peripherique et le petabolisme des myocytes cardiaquesread more
Citations
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Journal Article
Progression Models in Resistance Training for Healthy Adults
TL;DR: In this article, the optimal characteristics of strength-specific programs include the use of concentric (CON), eccentric (ECC), and isometric muscle actions and the performance of bilateral and unilateral single and multiple-joint exercises.
Journal ArticleDOI
Spinal and Supraspinal Factors in Human Muscle Fatigue
TL;DR: Evidence for "central" fatigue and the neural mechanisms underlying it are reviewed, together with its terminology and the methods used to reveal it.
Journal ArticleDOI
American College of Sports Medicine Position Stand. Progression Models in Resistance Training for Healthy Adults
William J. Kraemer,Kent J. Adams,Cafarelli E,Gary A. Dudley,C R. Dooly,Feigenbaum Ms,Steven J. Fleck,Franklin B,Andrew C. Fry,Hoffman,Robert U. Newton,Jeff A. Potteiger,Michael H. Stone,Nicholas A. Ratamess,Travis Triplett-McBride +14 more
TL;DR: In order to stimulate further adaptation toward a specific training goal(s), progression in the type of resistance training protocol used is necessary and emphasis should be placed on multiple-joint exercises, especially those involving the total body.
Journal ArticleDOI
Creatine and Creatinine Metabolism
Markus Wyss,Rima Kaddurah-Daouk +1 more
TL;DR: A comprehensive survey of the many intriguing facets of creatine (Cr) and creatinine metabolism is presented, encompassing the pathways and regulation of Cr biosynthesis and degradation, species and tissue distribution of the enzymes and metabolites involved, and of the inherent implications for physiology and human pathology.
Journal ArticleDOI
Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres
Jiandie D. Lin,Hai Wu,Paul T. Tarr,Chen-Yu Zhang,Zhidan Wu,Olivier Boss,Laura F. Michael,Pere Puigserver,Elji Isotani,Eric N. Olson,Bradford B. Lowell,Rhonda S Bassel-Duby,Bruce M. Spiegelman +12 more
TL;DR: Using fibre-type-specific promoters, it is shown in cultured muscle cells that PGC-1α activates transcription in cooperation with Mef2 proteins and serves as a target for calcineurin signalling, which has been implicated in slow fibre gene expression.
References
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Journal ArticleDOI
Adaptations of skeletal muscle to endurance exercise and their metabolic consequences
J. O. Holloszy,Edward F. Coyle +1 more
TL;DR: The major metabolic consequences of the adaptations of muscle to endurance exercise are a slower utilization of muscle glycogen and blood glucose, a greater reliance on fat oxidation, and less lactate production during exercise of a given intensity.
Journal ArticleDOI
Diet, Muscle Glycogen and Physical Performance
TL;DR: It has been shown that the glycogen content and, consequently, the long-term work capacity can be appreciably varied by instituting different diets after glycogen depletion.
Journal ArticleDOI
Biochemical Adaptations in Muscle EFFECTS OF EXERCISE ON MITOCHONDRIAL OXYGEN UPTAKE AND RESPIRATORY ENZYME ACTIVITY IN SKELETAL MUSCLE
TL;DR: The increase in electron transport capacity was associated with a concomitant rise in the capacity to produce adenosine triphosphate, which may partially account for the increase in aerobic work capacity that occurs with regularly performed, prolonged exercise.
Journal ArticleDOI
Starvation in man.
TL;DR: In this article, it was shown that decreased levels of active T3 may play a role by sparing otherwise obligated calories by decreasing metabolic needs, but this can be nullified by amino acid or protein supplementation.
Journal ArticleDOI
Hyperpolarizing vasodilators activate ATP-sensitive K+ channels in arterial smooth muscle.
TL;DR: In arterial rings the vasorelaxing actions of the drugs diazoxide, cromakalim, and pinacidil and the hyperpolarizing actions of vasoactive intestinal polypeptide and acetylcholine were blocked by inhibitors of the ATP-sensitive K+ channels, suggesting that all these agents may act through a common pathway in smooth muscle by opening ATP- sensitivity channels.
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Adaptations of skeletal muscle to endurance exercise and their metabolic consequences
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