Journal ArticleDOI
Nanosystems in Drug Targeting: Opportunities and Challenges
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This article is published in Current Nanoscience.The article was published on 2005-01-01. It has received 377 citations till now. The article focuses on the topics: Targeted drug delivery.read more
Citations
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Cytotoxicity of functionalized polystyrene latex nanoparticles toward lactic acid bacteria, and comparison with model microbes
TL;DR: The cytotoxicity and colloidal behavior of surface-functionalized polystyrene latex (PSL) nanoparticles (NPs) toward a model gram positive bacterium Lactococcus lactis JCM 5805 indicated that the cells were damaged by the cell disruption that resulted from the adhesion of the NPs to the cell surface.
Journal ArticleDOI
Intravesical delivery of 5‐aminolevulinic acid from water‐in‐oil nano/submicron‐emulsion systems
TL;DR: Water-in-oil (w/o) emulsions for the intravesical administration of 5-aminolevulinic acid (ALA) provide a significant advantage for drugs targeting bladder tissues.
Journal ArticleDOI
Conjugates of gonadotropin releasing hormone (GnRH) with carminic acid: Synthesis, generation of reactive oxygen species (ROS) and biological evaluation.
Vered Lev-Goldman,B. Mester,Nurit Ben-Aroya,Tamar Hanoch,Barbara Rupp,Tsvetanka Stanoeva,Georg Gescheidt,Rony Seger,Yitzhak Koch,Lev Weiner,Mati Fridkin +10 more
TL;DR: It is found that the CA-GnRH conjugates preserved the bioactivity of GnRH as illustrated by their capability to induce ERK phosphorylation and LH release, and used electron spin resonance (ESR) and spin trapping techniques to study the light-stimulated redox properties of CA.
Journal ArticleDOI
Solid Lipid Nanoparticles Containing Nimesulide: Preparation, Characterization and Cytotoxicity Studies
Maria Luisa Bondì,Antonina Azzolina,Emanuela Fabiola Craparo,Giulia Capuano,Nadia Lampiasi,Gaetano Giammona,Melchiorre Cervello +6 more
TL;DR: These SLN containing nimesulide show good loading capacity and drug release profile, and an in vitro antitumour activity comparable to free drug, and the antiproliferative effect of drug-loaded SLN versus free drug on HT-29 and SW-480 cell lines was here evaluated.
Journal ArticleDOI
Brain targeted delivery of sumatriptan succinate loaded chitosan nanoparticles: Preparation, In vitro characterization, and (Neuro-)pharmacokinetic evaluations
TL;DR: Neuropharmacokinetic evaluations of the polymeric nanoparticles represent a suitable brain delivery system and the high DTP value for nanoparticles confirms the satisfactory entrance of the drug into the higher parts of the brain.
References
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Book
Liposomes: From Physics to Applications
TL;DR: Part 1 General Introduction to Liposomes: Chemistry of lipids and liposomes and applications in Basic Sciences and Pharmacology and Medicine.
Book
Encyclopedia Of Controlled Drug Delivery
TL;DR: The 70 entries offer A-to-Z coverage of controlled drug delivery systems for researchers in the pharmaceutical and biotechnology industries, agriculture companies, medical device companies, clinical research organizations and medical schools.
BookDOI
Scientific and clinical applications of magnetic carriers
TL;DR: Preparation and Modification of Biodegradable Magnetic Particles: Preparation and Application of Monosized magnetic Particles in Selective Cell Separation and Applications in Molecular Biology and Drug Delivery and Radionuclide Therapy.
Book
Microencapsulation : methods and industrial applications
TL;DR: Methods of Encapsulation and Advances in Production Technology a Survey of Microencapsulation Processes, Curt Thies.
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A New Concept for Macromolecular Therapeutics in Cancer Chemotherapy: Mechanism of Tumoritropic Accumulation of Proteins and the Antitumor Agent Smancs
Yasuhiro Matsumura,Hiroshi Maeda +1 more