Journal ArticleDOI
Nanosystems in Drug Targeting: Opportunities and Challenges
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This article is published in Current Nanoscience.The article was published on 2005-01-01. It has received 377 citations till now. The article focuses on the topics: Targeted drug delivery.read more
Citations
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Turning biopolymer particles into hybrid capsules: the example of silica/alginate nanocomposites
Michel Boissière,Philippa J. Meadows,Roberta Brayner,Christophe Hélary,Jacques Livage,Thibaud Coradin +5 more
TL;DR: This paper demonstrates that some of these approaches can be easily adapted for the design of hybrid nanocapsules and shows that these new nanocomposites should be suitable for targeted drug delivery applications.
Journal ArticleDOI
Andrographolide nanoparticles in leishmaniasis: characterization and in vitro evaluations.
TL;DR: Antileishmanial activity was found to be significant for the nanoparticle preparation with 4% PVA in about one-fourth of the dosage of the pure compound AG (IC50 160 μM), which have significant potential to target the infested macrophage cells and prove valuable in chemotherapy of neglected tropical diseases such as leishmaniasis.
Journal ArticleDOI
Enzyme-directed assembly of a nanoparticle probe in tumor tissue.
Miao-Ping Chien,Matthew P. Thompson,Christopher V. Barback,Ti-Hsuan Ku,David J. Hall,Nathan C. Gianneschi +5 more
TL;DR: Enzyme-directed assembly in vivo: A targeting strategy is demonstrated, which leads to an active accumulation of nanoparticles by virtue of an assembly event specific to endogenous, enzymatic biochemical signals associated with tumor tissue.
Journal ArticleDOI
Polymere Therapeutika: Konzepte und Anwendungen
Rainer Haag,Felix Kratz +1 more
TL;DR: In this paper aufsatz geben wir einen Uberblick uber polymere Therapeutika with einem Schwerpunkt auf Konzepten und beispielen, die die besonderen Merkmale des jeweiligen Wirkstofftransport systems charakterisieren.
Journal ArticleDOI
Cisplatin encapsulated in phosphatidylethanolamine liposomes enhances the in vitro cytotoxicity and in vivo intratumor drug accumulation against melanomas.
TL;DR: It is demonstrated that PE liposomes represent a potentially useful strategy for targeting cisplatin delivery into melanomas, and had higher cytotoxicity than classic liposome or free cisPlatin.
References
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Book
Liposomes: From Physics to Applications
TL;DR: Part 1 General Introduction to Liposomes: Chemistry of lipids and liposomes and applications in Basic Sciences and Pharmacology and Medicine.
Book
Encyclopedia Of Controlled Drug Delivery
TL;DR: The 70 entries offer A-to-Z coverage of controlled drug delivery systems for researchers in the pharmaceutical and biotechnology industries, agriculture companies, medical device companies, clinical research organizations and medical schools.
BookDOI
Scientific and clinical applications of magnetic carriers
TL;DR: Preparation and Modification of Biodegradable Magnetic Particles: Preparation and Application of Monosized magnetic Particles in Selective Cell Separation and Applications in Molecular Biology and Drug Delivery and Radionuclide Therapy.
Book
Microencapsulation : methods and industrial applications
TL;DR: Methods of Encapsulation and Advances in Production Technology a Survey of Microencapsulation Processes, Curt Thies.
Related Papers (5)
A New Concept for Macromolecular Therapeutics in Cancer Chemotherapy: Mechanism of Tumoritropic Accumulation of Proteins and the Antitumor Agent Smancs
Yasuhiro Matsumura,Hiroshi Maeda +1 more