New Developments of Ti-Based Alloys for Biomedical Applications
TLDR
Efforts have been made to reveal the latest scenario of bulk and porous Ti-based materials for biomedical applications, emphasizing their current status, future opportunities and obstacles for expanded applications.Abstract:
Ti-based alloys are finding ever-increasing applications in biomaterials due to their excellent mechanical, physical and biological performance. Nowdays, low modulus β-type Ti-based alloys are still being developed. Meanwhile, porous Ti-based alloys are being developed as an alternative orthopedic implant material, as they can provide good biological fixation through bone tissue ingrowth into the porous network. This paper focuses on recent developments of biomedical Ti-based alloys. It can be divided into four main sections. The first section focuses on the fundamental requirements titanium biomaterial should fulfill and its market and application prospects. This section is followed by discussing basic phases, alloying elements and mechanical properties of low modulus β-type Ti-based alloys. Thermal treatment, grain size, texture and properties in Ti-based alloys and their limitations are dicussed in the third section. Finally, the fourth section reviews the influence of microstructural configurations on mechanical properties of porous Ti-based alloys and all known methods for fabricating porous Ti-based alloys. This section also reviews prospects and challenges of porous Ti-based alloys, emphasizing their current status, future opportunities and obstacles for expanded applications. Overall, efforts have been made to reveal the latest scenario of bulk and porous Ti-based materials for biomedical applications.read more
Citations
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Journal ArticleDOI
Oxidation treatments of beta-type Ti-40Nb for biomedical use
A. Gebert,Dimitri Eigel,Petre Flaviu Gostin,Volker Hoffmann,M. Uhlemann,Arne Helth,Stefan Pilz,Romy Schmidt,Mariana Calin,Markus Göttlicher,Marcus Rohnke,Jürgen Janek +11 more
TL;DR: In this article, different anodization methods for surface oxidation were evaluated and oxide layers with characteristic morphologies were obtained and obtained oxide types appear to be promising as coatings of beta-type implants with appropriate bioactivity to stimulate bone growth.
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The Crosstalk between Mesenchymal Stem Cells and Macrophages in Bone Regeneration: A Systematic Review
TL;DR: In this article, a systematic literature review of mesenchymal stem cells and macrophages during bone regeneration is presented. But, the precise mechanisms by which macrophage subtypes influence bone regeneration and how MSCs communicate with macophages have not yet been fully elucidated.
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Strength-ductility improvement of extruded Ti-(N) materials using pure Ti powder with high nitrogen solution
Ammarueda Issariyapat,Patama Visuttipitukul,Tingting Song,Junko Umeda,Ma Qian,Katsuyoshi Kondoh +5 more
TL;DR: In this article, the Hall-Petch equation and Labusch model were used to quantitatively evaluate the mechanism for the α-Ti grain refinement and solid solution strengthening effects of Ti-(N) powder metallurgy materials.
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Osteogenic activity of a titanium surface modified with silicon-doped titanium dioxide.
TL;DR: A coating consisting of microporous titanium doped with silicon (Si-TiO2) was successfully created by microarc oxidation (MAO), and Si was evenly distributed on the surface of the coating.
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Formation of Micro- and Nanostructures on the Nanotitanium Surface by Chemical Etching and Deposition of Titania Films by Atomic Layer Deposition (ALD)
TL;DR: Comparative study of the adhesive and spreading properties of human osteoblasts MG-63 has demonstrated that presence of nano- and microscale structures and crystalline titanium oxide on the surface of nanotitanium improve bioactive properties of the material.
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