New Developments of Ti-Based Alloys for Biomedical Applications
TLDR
Efforts have been made to reveal the latest scenario of bulk and porous Ti-based materials for biomedical applications, emphasizing their current status, future opportunities and obstacles for expanded applications.Abstract:
Ti-based alloys are finding ever-increasing applications in biomaterials due to their excellent mechanical, physical and biological performance. Nowdays, low modulus β-type Ti-based alloys are still being developed. Meanwhile, porous Ti-based alloys are being developed as an alternative orthopedic implant material, as they can provide good biological fixation through bone tissue ingrowth into the porous network. This paper focuses on recent developments of biomedical Ti-based alloys. It can be divided into four main sections. The first section focuses on the fundamental requirements titanium biomaterial should fulfill and its market and application prospects. This section is followed by discussing basic phases, alloying elements and mechanical properties of low modulus β-type Ti-based alloys. Thermal treatment, grain size, texture and properties in Ti-based alloys and their limitations are dicussed in the third section. Finally, the fourth section reviews the influence of microstructural configurations on mechanical properties of porous Ti-based alloys and all known methods for fabricating porous Ti-based alloys. This section also reviews prospects and challenges of porous Ti-based alloys, emphasizing their current status, future opportunities and obstacles for expanded applications. Overall, efforts have been made to reveal the latest scenario of bulk and porous Ti-based materials for biomedical applications.read more
Citations
More filters
Journal ArticleDOI
Synthetic bone: Design by additive manufacturing.
TL;DR: A conceptual bio-engineering design methodology for new biomedical lattices produced by additive manufacturing is presented, which addresses some of the critical points in currently existing porous implant materials, including feasibility and accuracy of manufacturing, design to the elastic properties of bone, and sensible pores sizes for osseointegration.
Journal ArticleDOI
A review of biomimetic surface functionalization for bone-integrating orthopedic implants: Mechanisms, current approaches, and future directions
Callum Stewart,Behnam Akhavan,Behnam Akhavan,Steven G. Wise,Steven G. Wise,Marcela M.M. Bilek +5 more
TL;DR: This approach seeks to promote osteoblast differentiation and bone formation at the implant surface, leading to integration between the orthopedic surface and the local bone tissue, and the need for biomimetic functionalization from a materials and biological perspective is highlighted.
Journal ArticleDOI
Phase transition, microstructural evolution and mechanical properties of Ti-Nb-Fe alloys induced by Fe addition
TL;DR: In this article, the phase and properties of the alloys depend on Fe additions, and the results suggest that Ti-11Nb-9Fe is a promising candidate for biomedical applications.
Journal ArticleDOI
Recent Development in Beta Titanium Alloys for Biomedical Applications
TL;DR: A broad and extensive review of β-type Ti alloys in terms of alloy design, preparation methods, mechanical properties, corrosion behavior, and biocompatibility is provided in this article.
Journal ArticleDOI
Mechanical properties and biocompatibility of porous titanium scaffolds for bone tissue engineering.
Yunhui Chen,Jessica E. Frith,Ali Dehghan-Manshadi,Hooyar Attar,Damon Kent,Nicolas Soro,Michael Bermingham,Matthew S. Dargusch +7 more
TL;DR: It is concluded that samples with 30% porosity exhibit the best biocompatibility and suggest that porous titanium scaffolds generated using this manufacturing route have excellent potential for hard tissue engineering applications.
References
More filters
Book
Cellular Solids: Structure and Properties
Lorna J. Gibson,Michael F. Ashby +1 more
TL;DR: The linear elasticity of anisotropic cellular solids is studied in this article. But the authors focus on the design of sandwich panels with foam cores and do not consider the properties of the materials.
Journal ArticleDOI
Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030.
TL;DR: These large projected increases in demand for total hip and knee arthroplasties provide a quantitative basis for future policy decisions related to the numbers of orthopaedic surgeons needed to perform these procedures and the deployment of appropriate resources to serve this need.
Journal ArticleDOI
Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
Journal ArticleDOI
Stabilization of metallic supercooled liquid and bulk amorphous alloys
TL;DR: In this article, the authors investigated the stabilization properties of the supercooled liquid for a number of alloys in the Mg-, lanthanide-, Zr-, Ti-, Fe-, Co-, Pd-Cu- and Ni-based systems.
Journal ArticleDOI
Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Related Papers (5)
Ti based biomaterials, the ultimate choice for orthopaedic implants – A review
Development of new metallic alloys for biomedical applications
Titanium alloys in total joint replacement—a materials science perspective
Marc Long,H.J Rack +1 more