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New Developments of Ti-Based Alloys for Biomedical Applications

TLDR
Efforts have been made to reveal the latest scenario of bulk and porous Ti-based materials for biomedical applications, emphasizing their current status, future opportunities and obstacles for expanded applications.
Abstract
Ti-based alloys are finding ever-increasing applications in biomaterials due to their excellent mechanical, physical and biological performance. Nowdays, low modulus β-type Ti-based alloys are still being developed. Meanwhile, porous Ti-based alloys are being developed as an alternative orthopedic implant material, as they can provide good biological fixation through bone tissue ingrowth into the porous network. This paper focuses on recent developments of biomedical Ti-based alloys. It can be divided into four main sections. The first section focuses on the fundamental requirements titanium biomaterial should fulfill and its market and application prospects. This section is followed by discussing basic phases, alloying elements and mechanical properties of low modulus β-type Ti-based alloys. Thermal treatment, grain size, texture and properties in Ti-based alloys and their limitations are dicussed in the third section. Finally, the fourth section reviews the influence of microstructural configurations on mechanical properties of porous Ti-based alloys and all known methods for fabricating porous Ti-based alloys. This section also reviews prospects and challenges of porous Ti-based alloys, emphasizing their current status, future opportunities and obstacles for expanded applications. Overall, efforts have been made to reveal the latest scenario of bulk and porous Ti-based materials for biomedical applications.

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Review on titanium and titanium based alloys as biomaterials for orthopaedic applications.

TL;DR: Various attempts to improve upon these properties like different processing routes, surface modifications have been inculcated in the paper to provide an insight into the extent of research and effort that has been put into developing a highly superior titanium orthopaedic implant.
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Selective Laser Melting of Titanium Alloys and Titanium Matrix Composites for Biomedical Applications: A Review†

TL;DR: In this article, the authors reviewed the recent progresses in selective laser melting of titanium alloys and their composites for biomedical applications, especially developing new titanium powder for SLM, and extended attractive progresses in the SLM of all types of titanium, composites and porous structures including Ti-24Nb-4Zr-8Sn and Ti-TiB/TiC composites with focus on the manufacture by SLM and resulting unique microstructure and properties.
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Corrosion of Metallic Biomaterials: A Review

TL;DR: The body environment is analysed in detail and the possible effects of the corrosion of different biomaterials on biocompatibility are discussed, followed by description of the most common corrosion processes in vivo.
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Titanium nanostructures for biomedical applications

TL;DR: Perhaps the most spectacular and surprising one-dimensional structures and their unique biomedical applications for increased osseointegration, protein interaction and antibacterial properties are focused on.
References
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Journal ArticleDOI

Aligned porous alumina ceramics with high compressive strengths for bone tissue engineering

TL;DR: In this paper, the authors fabricated highly aligned porous alumina ceramics with interconnection sizes of >50μm by the unidirectional freeze casting of ceramic/camphene slurries at 3°C and subsequent treatment at 35°C for 24h, followed by sintering at 1600 Âm for 3Âh.
Journal ArticleDOI

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TL;DR: Studies on titanium made by implanting into subcutaneous tissue of rabbits, and femora of rats, have demonstrated that titanium is an inert metal which appears to be ideal for fixation of fractures.
Journal ArticleDOI

Design and fabrication of standardized hydroxyapatite scaffolds with a defined macro-architecture by rapid prototyping for bone-tissue-engineering research

TL;DR: This investigation describes the production and characterization of calcium phosphate scaffolds with defined and reproducible porous macro-architectures and their preliminary in vitro and in vivo bone-tissue-engineered response.
Journal ArticleDOI

Mechanical properties of open-pore titanium foam.

TL;DR: The analyzed foams are found to be anisotropic due to the use of nonspherical space holder particles which rearrange during the compaction of the powder mixture.
Journal ArticleDOI

Rapid prototyped porous titanium coated with calcium phosphate as a scaffold for bone tissue engineering

TL;DR: It is demonstrated that porous Ti scaffolds with high strength and defined geometry may be evenly coated with CaP layers and cultured mesenchymal stem cells for bone tissue engineering.
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