Nutritional genomics and personalized diet
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TLDR
Interaction of genetic background and diet with regard to development of such life threatening chronic conditions as obesity, cardiovascular disease (CVD), and cancer that are responsible for the majority of deaths in developed Western countries are focused upon.About:
This article is published in Egyptian Journal of Medical Human Genetics.The article was published on 2011-05-01 and is currently open access. It has received 19 citations till now. The article focuses on the topics: Nutrigenomics & Nutrigenetics.read more
Citations
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Journal ArticleDOI
Dietary Fatty Acid Composition Modulates Obesity and Interacts with Obesity-Related Genes
Shatha S Hammad,Peter B. Jones +1 more
TL;DR: The evidence is not only supporting the modulatory effect of fat quality on obesity development but also presenting a number of interactions between obesity-related genes and the quality of dietary fat, which holds a promise for the possibility of using genetically targeted dietary interventions to reduce obesity risk in the future.
Journal ArticleDOI
Tackling Atherosclerosis via Selected Nutrition
TL;DR: For the prevention of atherosclerosis through personalized nutrition, it is necessary to analyze the genetic characteristics (SNP) associated with the metabolism of nutrients, to assess the state of the microbiota of the GIT.
Dissertation
Nutrigenetika i prevencija metaboličkog sindroma
TL;DR: U nastanku metabolickog sindroma (MetS) cini se da geneticko ustrojstvo ima znacajnu ulogu, a zbog njegove povezanosti s kardiovaskularnim bolesti
Journal ArticleDOI
Modulation of dietary folate with age confers selective hepatocellular epigenetic imprints through DNA methylation.
Rauf Ahmad Najar,Nissar Ahmad Wani,Javeed Ahmad Bhat,Nawab John Dar,Beenish Rahat,Ajai Prakash Gupta,Jaspreet Kaur,Jyotdeep Kaur,Abid Hamid +8 more
TL;DR: Folate deficiency with age resulted in the up-regulation of proto-oncogenes and cell cycle regulator gene Cyclin E as a result of promoter hypomethylation and promoter hypermethylation, respectively, which may contribute toward the pathogenesis at cellular level.
Journal ArticleDOI
Nutrigenomic Approach in Understanding the Antiallergic Effects of Curcumin
TL;DR: A novel potential of curcumin is suggested for utilization in prevention or management of allergic diseases.
References
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Journal ArticleDOI
Obesity as a medical problem
TL;DR: The global epidemic of obesity results from a combination of genetic susceptibility, increased availability of high-energy foods and decreased requirement for physical activity in modern society, and should be regarded as an epidemic that threatens global well being.
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Atherosclerosis: The Road Ahead
TL;DR: Elevated levels of serum cholesterol are probably unique through the hepatic LDL receptor pathway, as evi-in being sufficient to drive the development of athero-denced by the fact that lack of functional LDL receptors sclerosis in humans and experimental animals, even in is responsible for the massive accumulation of LDL in the absence of other known risk factors.
Journal Article
Atherosclerosis : Vascular biology
TL;DR: It is now clear that atherosclerosis is not simply an inevitable degenerative consequence of ageing, but rather a chronic inflammatory condition that can be converted into an acute clinical event by plaque rupture and thrombosis.
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Cancer chemoprevention with dietary phytochemicals
TL;DR: Attention has recently been focused on intracellular-signalling cascades as common molecular targets for various chemopreventive phytochemicals.
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A high-resolution recombination map of the human genome
Augustine Kong,Daniel F. Gudbjartsson,Jesus Sainz,Gudrun M. Jonsdottir,Sigurjon A. Gudjonsson,Bjorgvin Richardsson,Sigrun Sigurdardottir,John Barnard,Bjorn Hallbeck,Gisli Masson,Adam Shlien,Stefan T Palsson,Michael L. Frigge,Thorgeir E. Thorgeirsson,Jeffrey R. Gulcher,Kari Stefansson +15 more
TL;DR: Recombination rates are significantly correlated with both cytogenetic structures and sequence and paternal chromosomes show many differences in locations of recombination maxima, suggesting that there is some underlying component determined by both genetic and environmental factors that affects maternal recombination rates.