Journal ArticleDOI
One-Pot Three-Component Synthesis of 3-Methyl-4-Arylmethylene- Isoxazol-5(4H)- Ones Catalyzed by Sodium Sulfide
Qing Liu,Xianming Hou +1 more
TLDR
In this paper, 3-Methyl-4-arylmethylene-isoxazol-5(4H)-ones were synthesized by the convenient three-component reaction of ethyl acetoacetate, hydroxylamine hydrochloride, and aromatic aldehydes catalyzed by sodium sulfide.Abstract:
3-Methyl-4-arylmethylene-isoxazol-5(4H)-ones were synthesized by the convenient three-component reaction of ethyl acetoacetate, hydroxylamine hydrochloride, and aromatic aldehydes catalyzed by sodium sulfide in the presence of ethanol at room temperature. The advantages of this procedure were mild reaction conditions, high yields, short reaction time, and operational simplicity.read more
Citations
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Journal ArticleDOI
Synthesis of Arylmethylidene-isoxazol-5(4H)-ones via Three-Component Reaction in Water Catalyzed by Sodium Tetraborate
Hamzeh Kiyani,Fatemeh Ghorbani +1 more
TL;DR: Arylmethylidene-isoxazol-5(4H)-ones have been prepared via a one-pot, three-component cyclocondensation process between aromatic aldehydes, ethyl acetoacetate, and hydroxylamine hydrochloride in good yields.
Journal ArticleDOI
Cu/TCH-pr@SBA-15 nano-composite: a new organometallic catalyst for facile three-component synthesis of 4-arylidene-isoxazolidinones
TL;DR: In this paper, a copper complex supported on SBA-15 nanoparticles (Cu/TCH-pr@SBA-2015) was synthesized by the post-synthesis modification of nano-mesoporous silica with 3-chloropropyltriethoxysilane (CPTES) and thiocarbohydrazide (TCH) and subsequent metal-ligand coordination with Cu(II).
Journal ArticleDOI
A facile and environmental-friendly protocol for the synthesis of methyleneisoxazole-5(4H)-ones catalyzed by CeO2/TiO2 under ultrasonic irradiation
TL;DR: In this paper , a novel and efficient nanocomposite is synthesized by deposition-precipitation approach, characterized by FE-SEM, SEM-EDX, P-XRD, TEM, TGA and BET analyses.
Journal ArticleDOI
Vitamin B 1 ‐Catalyzed Multicomponent Reaction for Efficient Synthesis of an Isoxazolone Compound by Using Ultrasound in a Water and Its Selective Identification of Metal Ions
TL;DR: An efficient synthesis of 3-methyl-4-(arylmethylene)isoxazol-5(4H)-ones is developed via cyclocondensation in 84-94 % yields starting from aromatic aldehydes, hydroxylamine with ethyl acetoacetate vitamin B1 is catalyzed under ultrasound radiation, and are characterized by HR-MS, FT-IR and 1H and 13C NMR spectroscopy as mentioned in this paper .
Journal ArticleDOI
Introduction of [2,2'-Bipyridine]-1,1'-Diium Perchlorate as a Novel and Highly Efficient Dicationic Brönsted Acidic Organic Salt for the Synthesis of 3-Methyl-4-Arylmethylene Isoxazole-5(4H)-One Derivatives in Water
References
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Journal ArticleDOI
Multicomponent Reactions with Isocyanides.
Alexander Dömling,Ivar Ugi +1 more
TL;DR: MCRs and especially MCRs with isocyanides offer many opportunities to attain new reactions and basic structures, however, this requires that the chemist learns the "language" of M CRs, something that this review wishes to stimulate.
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Yong Koo Kang,Kye Jung Shin,Kyung Ho Yoo,Kyung Jae Seo,Chang Yong Hong,Chang Seok Lee,Seung Yong Park,Dong Jin Kim,Sang Woo Park +8 more
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A practical and green approach towards synthesis of dihydropyrimidinones: using heteropoly acids as efficient catalysts.
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TL;DR: This method provides an efficient and much improved modification of the original Biginelli reaction in terms of high yields, and short reaction times, and has the ability to allow a wide variety of substitutions in all three components.
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