Orodispersible films: Towards drug delivery in special populations.
Mariagiovanna Scarpa,Sven Stegemann,Wen Kai Hsiao,Heinz Pichler,Simon Gaisford,Massimo Bresciani,Amrit Paudel,Mine Orlu +7 more
TLDR
The current strides of ODF technology and some of its unmet quality and manufacturing aspects are reviewed, which highlights opportunities and limitations of inkjet printed ODF as a population-specific drug delivery.About:
This article is published in International Journal of Pharmaceutics.The article was published on 2017-05-15 and is currently open access. It has received 73 citations till now.read more
Citations
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Personalized orodispersible films by hot melt ram extrusion 3D printing
Umberto M. Musazzi,Francesca Selmin,Marco Aldo Ortenzi,Garba Khalid Mohammed,Silvia Franzè,Paola Minghetti,Francesco Cilurzo +6 more
TL;DR: This work demonstrates the feasibility of the extemporaneous preparation of maltodextrins orodispersible films (ODF) by hot‐melt ram‐extrusion 3D printing, demonstrating the suitability of the proposed technology.
Journal ArticleDOI
Towards Printed Pediatric Medicines in Hospital Pharmacies: Comparison of 2D and 3D-Printed Orodispersible Warfarin Films with Conventional Oral Powders in Unit Dose Sachets
TL;DR: The aim of this study was to compare the currently used method to produce patient-tailored warfarin doses at HUS Pharmacy in Finland with two innovative printing techniques and demonstrates the potential of utilizing printing technologies for the production of on-demand patient-specific doses.
Journal ArticleDOI
New formulation and approach for mucoadhesive buccal film of rizatriptan benzoate
Sahar Salehi,Soheil Boddohi +1 more
TL;DR: The results suggest that RB-loaded mucoadhesive buccal films could be a potential candidate to achieve optimum drug release for effective treatment of migraine.
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Printing T3 and T4 oral drug combinations as a novel strategy for hypothyroidism
Mustafa Alomari,Parameswara Rao Vuddanda,Sarah J. Trenfield,Cornelius C. Dodoo,Sitaram P. Velaga,Abdul Basit,Simon Gaisford +6 more
TL;DR: The ability to produce personalised dose combinations by TIJ printing T3 and T4 onto the same substrate for oral administration for Hypothyroidism is demonstrated for the first time.
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3D printing of multilayered orodispersible films with in-process drying
TL;DR: The modified printing method shows great promise in a compounding production of personalized film dosage forms, and brings in possibilities such as one step preparation of films with compartmented drugs and incorporation of taste masking or release control layers.
References
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Capillary flow as the cause of ring stains from dried liquid drops
TL;DR: In this article, the authors ascribe the characteristic pattern of the deposition to a form of capillary flow in which pinning of the contact line of the drying drop ensures that liquid evaporating from the edge is replenished by liquid from the interior.
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Inkjet Printing—Process and Its Applications
TL;DR: This Progress Report provides an update on recent developments in inkjet printing technology and its applications, which include organic thin-film transistors, light-emitting diodes, solar cells, conductive structures, memory devices, sensors, and biological/pharmaceutical tasks.
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Inkjet Printing of Functional and Structural Materials: Fluid Property Requirements, Feature Stability, and Resolution
TL;DR: In this paper, the authors review the current state of understanding of the mechanisms of drop formation and how this defines the fluid properties that are required for a given liquid to be printable.
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Strategies to Address Low Drug Solubility in Discovery and Development
Hywel David Williams,Natalie L. Trevaskis,Susan A. Charman,Ravi Mysore Shanker,William N. Charman,Colin W. Pouton,Christopher J.H. Porter +6 more
TL;DR: The article provides an integrated and contemporary discussion of current approaches to solubility and dissolution enhancement but has been deliberately structured as a series of stand-alone sections to allow also directed access to a specific technology where required.
Journal Article
Medical Applications for 3D Printing: Current and Projected Uses.
TL;DR: 3D printing in medicine can provide many benefits, including: the customization and personalization of medical products, drugs, and equipment; cost-effectiveness; increased productivity; the democratization of design and manufacturing; and enhanced collaboration.