Q2. Who is the author of this article?
The authors thank G. Hidalgo (CCSS, Costa Rica) for technical assistance with the IHC and M. Domingo (CReSA, Spain) for collaboration with the morbillivirus detection assays and Fundación KETO.
Pathology of striped dolphins (Stenella coeruleoalba) infected with Brucella ceti.
Rocío González-Barrientos,Juan Morales,Gabriela Hernández-Mora,Elías Barquero-Calvo,Caterina Guzmán-Verri,Esteban Chaves-Olarte,Edgardo Moreno +6 more
Reads0
Chats0
TLDR
The severity of brucellosis in S. coeruleoalba indicates that this dolphin species is highly susceptible to infection by B. ceti.About:
This article is published in Journal of Comparative Pathology.The article was published on 2010-05-01 and is currently open access. It has received 66 citations till now. The article focuses on the topics: Brucella ceti & Stenella coeruleoalba.read more
Figures
Fig. 2. Microscopical findings detected in 17 S. coeruleoalba dolphins. 
Fig. 1. Gross pathological findings detected in 17 S. coeruleoalba dolphins. 
Table 1 Meningoencephalomyelitis, detection of anti-Brucella antibodies and B. ceti isolation in 17 stranded S. coeruleoalba dolphins 
Fig. 3. Pathological findings inB. ceti-infected S. coeruleoalba dolphins. (A) Coronal transverse section of the lateral caudal region of the left hemisphere of the brain. There is internal hydrocephalus with enlargement of the lateral ventricles due to cerebrospinal fluid accumulation secondary to inflammation surrounding the ventricular system. Arrow indicates a hyperaemic blood vessel. (B) Necrotizing placentitis showing marked infiltration of inflammatory cells into the fetal placental villi (arrow), submucosal oedema and hyperaemic blood vessels. HE. 4. (C) Placental villi with inflammatory infiltrate and some detached placental epithelial cells (arrowed). HE. 40. (D) Labelling ofBrucella antigen within inflammatory cells invading the placental villi (example arrowed). IHC. 40. (E) Vegetative nodule in the mitral valve (white arrow) of the heart and hyperaemic blood vessels in the dorsal region of the valve (black arrow). (F)Microscopical appearance of themitral valve shown in (E) with bacterial colonies (arrow) and fibrin deposition HE, 40. (G) Section from the mitral valve shown in (E) demonstrating Brucella antigen (arrow) and labelled bacterial aggregates. IHC. 10. (H) Section from the mitral valve shown in (E) demonstrating Brucella antigen within phagocytic cells and some probable bacterial aggregates (arrow). IHC. 40.
Citations
More filters
Journal ArticleDOI
Diagnosis of Brucellosis in Livestock and Wildlife
TL;DR: The diagnosis of brucellosis in livestock and wildlife is complex and serological results need to be carefully analyzed.
Journal ArticleDOI
What have we learned from brucellosis in the mouse model
María Jesús Grilló,José M. Blasco,Jean-Pierre Gorvel,Jean-Pierre Gorvel,Jean-Pierre Gorvel,Ignacio Moriyón,Edgardo Moreno +6 more
TL;DR: It is concluded that, when used properly, the mouse is a valuable brucellosis model and a useful virulence/attenuation index and is used in vaccine (Residual Virulence) quality control.
Journal ArticleDOI
An evolutionary strategy for a stealthy intracellular Brucella pathogen
TL;DR: In this paper, the stealthy strategy used by Brucella to escape recognition of the innate immunity and the means by which this bacterium evades intracellular destruction are discussed.
Journal ArticleDOI
Advancement of knowledge of Brucella over the past 50 years.
S. C. Olsen,Mitchell V. Palmer +1 more
TL;DR: Although pathogenic Brucella spp have preferred reservoir hosts, their ability to infect numerous mammalian hosts has been increasingly documented and the maintenance of infection in new reservoirhosts, such as wildlife, has become an issue for both public health and animal health regulatory personnel.
Journal ArticleDOI
A review of Brucella infection in marine mammals, with special emphasis on Brucella pinnipedialis in the hooded seal (Cystophora cristata)
TL;DR: It is described how different molecular methods have contributed to species identification and differentiation of B. ceti and B. pinnipedialis, with special emphasis on the hooded seal isolates.
References
More filters
Book
Histological and Histochemical Methods: Theory and Practice
TL;DR: This text presents the chemical and physical principles of fixation, staining and histochemistry, and offers a practical guide to the preparation of specimens for light microscopy and includes detailed practical instructions of the techniques used.
Journal ArticleDOI
Human Neurobrucellosis with Intracerebral Granuloma Caused by a Marine Mammal Brucella spp.
Annette H. Sohn,Will S. Probert,Carol A. Glaser,Nalin Gupta,Andrew W. Bollen,Jane D. Wong,Elizabeth Grace,William C. McDonald +7 more
TL;DR: The first report of community-acquired human infections with marine mammal–associated Brucella spp.
Journal ArticleDOI
Brucella abortus uses a stealthy strategy to avoid activation of the innate immune system during the onset of infection.
Elías Barquero-Calvo,Esteban Chaves-Olarte,David S. Weiss,Caterina Guzmán-Verri,Carlos Chacón-Díaz,Alexandra Rucavado,Ignacio Moriyón,Edgardo Moreno +7 more
TL;DR: It is proposed that Brucella has developed a stealth strategy through PAMPs reduction, modification and hiding, ensuring by this manner low stimulatory activity and toxicity for cells.
Journal ArticleDOI
Characteristics of a Brucella species from a bottlenose dolphin (Tursiops truncatus)
TL;DR: Biochemical and oxidative metabolism profiles indicated that the isolate belongs in the genus Brucella but did not match the profiles of any established species or biovars.
Journal ArticleDOI
Clinical categories of neurobrucellosis. A report on 19 cases.
TL;DR: awareness of the condition and performance of the appropriate serological tests will differentiate neurobrucellosis from other chronic CNS infections, especially tuberculosis and neurosyphilis.