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Journal ArticleDOI

Peptides and the origin of life1

Bernd M. Rode
- 01 Aug 1999 - 
- Vol. 20, Iss: 6, pp 773-786
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TLDR
The salt-induced peptide formation reaction in connection with adsorption processes on clay minerals would appear to be the simplest and most universal mechanism known to date for chemical peptide evolution.
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This article is published in Peptides.The article was published on 1999-08-01. It has received 290 citations till now.

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Prebiotic systems chemistry: new perspectives for the origins of life.

TL;DR: This paper presents a probabilistic analysis of the stationary phase replacement of Na6(CO3)(SO4)/ Na2SO4 in horseshoe clusters and shows clear trends in the number of stationary phases and in the stationary phases of Na2CO3.
Journal ArticleDOI

Adsorption and Polymerization of Amino Acids on Mineral Surfaces: A Review

TL;DR: A review of recent (post-1980) work on amino acid adsorption and thermal reactivity on oxide and sulfide minerals and a discussion of future work needed to fill the most conspicuous gaps in knowledge of amino acids/mineral surfaces systems and their reactivity.
Journal ArticleDOI

Origins of building blocks of life: A review

TL;DR: This review of reported experimental and theoretical findings for prebiotic chemistry relevant to this topic summary indicates that life's origin did not occur at a single setting; rather, it required highly diverse and dynamic environments that were connected with each other to allow intra-transportation of reaction products and reactants through fluid circulation.
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Ester‐Mediated Amide Bond Formation Driven by Wet–Dry Cycles: A Possible Path to Polypeptides on the Prebiotic Earth

TL;DR: A prebiotically plausible mechanism for peptide (amide) bond formation that is enabled by α-hydroxy acids is demonstrated, which supports a long-standing hypothesis that peptides might have arisen from ester-based precursors.
References
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A Production of Amino Acids Under Possible Primitive Earth Conditions

TL;DR: In this study, an apparatus was built to circulate CHI4, NH3, H2O, and H2 past an electric discharge, and the resulting mixture has been tested for amino acids by paper chromatography.
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Evidence for life on Earth before 3,800 million years ago.

TL;DR: In this article, ion-microprobe measurements of the carbon-isotope composition of carbonaceous inclusions within grains of apatite (basic calcium phosphate) from the oldest known sediment sequences a approx. 3,800 Myr-old banded iron formation from the Isua supracrustal belt, West Greenland and a similar formation from Akilia island that is possibly older than 3,850 Myr.
Journal ArticleDOI

Autocatalytic sets of proteins.

TL;DR: The main conclusions appear independent of the idealizations of the initial model, introduce a novel kind of parallel selection for peptides catalyzing connected sequences of reactions, depend upon a new kind of minimal critical complexity whose properties are definable, and suggest that the emergence of self replicating systems may be a self organizing collective property of critically complex protein systems in prebiotic evolution.
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