Permanent His-bundle pacing: a systematic literature review and meta-analysis
Francesco Zanon,Kenneth A. Ellenbogen,Gopi Dandamudi,Parikshit S. Sharma,Weijian Huang,Daniel L. Lustgarten,Roderick Tung,Hiroshi Tada,Jayanthi N. Koneru,Tracy L. Bergemann,Dedra H. Fagan,John Harrison Hudnall,Pugazhendhi Vijayaraman +12 more
TLDR
Permanent cardiac pacing of the His-bundle restores and retains normal electrical activation of the ventricles and improves left ventricular ejection fractions during follow-up.Abstract:
Aims Permanent cardiac pacing of the His-bundle restores and retains normal electrical activation of the ventricles. Data on His-bundle pacing (HBP) are largely limited to small single-centre reports, and clinical benefits and risks have not been systematically examined. We sought to systematically examine published studies of patients undergoing permanent HBP and quantify the benefits and risks of the therapy. Methods and results PubMed, Embase, and Cochrane Library were searched for full-text articles on permanent HBP. Clinical outcomes of interest included implant success rate, procedural and lead complications, pacing thresholds, QRS duration, and ejection fraction at follow-up, and mortality. Data were extracted and summarized. Where possible, meta-analysis of aggregate data was performed. Out of 2876 articles, 26 met the inclusion criteria representing 1438 patients with an implant attempt. Average age of patients was 73 years and 62.1% were implanted due to atrioventricular block. Overall average implant success rate was 84.8% and was higher with use of catheter-delivered systems (92.1%; P 3 months follow-up; although, pulse widths varied at testing. Average left ventricular ejection fractions (LVEFs) were 42.8% at baseline and 49.5% at follow-up. There were 43 complications observed in 907 patients across the 17 studies that reported safety information. Conclusion Among 26 articles of permanent HBP, the implant success rate averaged 84.8% and LVEF improved by an average of 5.9% during follow-up. Specific reporting of our clinical outcomes of interest varied widely, highlighting the need for uniform reporting in future HBP trials.read more
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2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy.
Michael Glikson,Jens Cosedis Nielsen,Mads Brix Kronborg,Yoav Michowitz,Angelo Auricchio,Israel M. Barbash,José A. Barrabés,Giuseppe Boriani,Frieder Braunschweig,Michele Brignole,Haran Burri,Andrew J.S. Coats,Jean-Claude Deharo,Victoria Delgado,Gerhard-Paul Diller,Carsten W. Israel,Andre Keren,Reinoud E. Knops,Dipak Kotecha,Christophe Leclercq,Béla Merkely,Christoph Starck,Ingela Thylén,José María Tolosana +23 more
Journal ArticleDOI
2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapyDeveloped by the Task Force on cardiac pacing and cardiac resynchronization therapy of the European Society of Cardiology (ESC) With the special contribution of the European Heart Rhythm Association (EHRA)
Michael Glikson,Jens Cosedis Nielsen,Mads Brix Kronborg,Yoav Michowitz,Angelo Auricchio,Israel M. Barbash,José A. Barrabés,Giuseppe Boriani,Frieder Braunschweig,Michele Brignole,Haran Burri,Andrew J.S. Coats,Jean-Claude Deharo,Victoria Delgado,Gerhard-Paul Diller,Carsten W. Israel,Andre Keren,Reinoud E. Knops,Dipak Kotecha,Christophe Leclercq,Béla Merkely,Christoph Starck,Ingela Thylén,José María Tolosana,Francisco Leyva,Cecilia Linde,Magdy Abdelhamid,Victor Aboyans,Elena Arbelo,Riccardo Asteggiano,Gonzalo Barón-Esquivias,Johann Bauersachs,Mauro Biffi,Ulrika Birgersdotter-Green,Maria Grazia Bongiorni,Michael A. Borger,Jelena Čelutkienė,Maja Čikeš,Jean-Claude Daubert,Inga Drossart,Kenneth A. Ellenbogen,Perry M. Elliott,Larissa Fabritz,Volkmar Falk,Laurent Fauchier,Francisco Fernández-Avilés,Dan Foldager,Fredrik Gadler,Pastora Gallego Garcia De Vinuesa,Bulent Gorenek,Jose M. Guerra,Kristina H. Haugaa,Jeroen M.L. Hendriks,Thomas Kahan,Hugo A. Katus,Aleksandra Konradi,Konstantinos C. Koskinas,Hannah Law,Basil S. Lewis,Nicholas J. Linker,Maja-Lisa Løchen,Joost Lumens,Julia Mascherbauer,Wilfried Mullens,Klaudia Vivien Nagy,Eva Prescott,Pekka Raatikainen,Amina Rakisheva,Tobias Reichlin,Renato Pietro Ricci,Evgeny Shlyakhto,Marta Sitges,Miguel Sousa-Uva,Richard Sutton,Piotr Suwalski,Jesper Hastrup Svendsen,Rhian M. Touyz,Isabelle C. Van Gelder,Kevin Vernooy,Johannes Waltenberger,Zachary I. Whinnett,Klaus K. Witte +81 more
Journal ArticleDOI
Prospective evaluation of feasibility and electrophysiologic and echocardiographic characteristics of left bundle branch area pacing
Pugazhendhi Vijayaraman,Faiz A. Subzposh,Angela Naperkowski,Ragesh Panikkath,Kaitlyn John,Vernon Mascarenhas,Terry D. Bauch,Weijian Huang +7 more
TL;DR: HBP and LBBAP may significantly increase the overall success of physiologic pacing and be feasible in a high percentage of patients with low thresholds during acute follow-up.
Journal ArticleDOI
Left Bundle Branch Pacing: JACC Review Topic of the Week.
TL;DR: The concept of pacing the conduction system distal to the His bundle to bypass the region of conduction block was proposed and the procedural feasibility of left bundle branch pacing was demonstrated.
Journal ArticleDOI
Long-Term Safety and Feasibility of Left Bundle Branch Pacing in a Large Single-Center Study.
Lan Su,Songjie Wang,Shengjie Wu,Lei Xu,Zhouqing Huang,Xiao Chen,Rujie Zheng,Limeng Jiang,Kenneth A. Ellenbogen,Zachary I. Whinnett,Weijian Huang +10 more
TL;DR: In this paper, left bundle branch branch pacing (LBBP) is used for pacing and has been observed to have low and stable pacing thresholds in prior small short-term studies.
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Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
TL;DR: The QUOROM Statement (QUality Of Reporting Of Meta-analyses) as mentioned in this paper was developed to address the suboptimal reporting of systematic reviews and meta-analysis of randomized controlled trials.
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Adverse Effect of Ventricular Pacing on Heart Failure and Atrial Fibrillation Among Patients With Normal Baseline QRS Duration in a Clinical Trial of Pacemaker Therapy for Sinus Node Dysfunction
Michael O. Sweeney,Anne S. Hellkamp,Kenneth A. Ellenbogen,Arnold J. Greenspon,Roger A. Freedman,Kerry L. Lee,Gervasio A. Lamas +6 more
TL;DR: Ventricular desynchronization imposed by ventricular pacing even when AV synchrony is preserved increases the risk of HF hospitalization and AF in SND with normal baseline QRSd.
Journal ArticleDOI
Permanent, Direct His-Bundle Pacing A Novel Approach to Cardiac Pacing in Patients With Normal His-Purkinje Activation
TL;DR: Permanent DHBP is feasible in select patients who have chronic atrial fibrillation and dilated cardiomyopathy and results in a reduction of left ventricular dimensions and improved cardiac function.
Journal ArticleDOI
His-bundle pacing versus biventricular pacing in cardiac resynchronization therapy patients: A crossover design comparison.
Daniel L. Lustgarten,Eric M. Crespo,Irina Arkhipova-Jenkins,Robert Lobel,Joseph F. Winget,Jodi Koehler,Evan Liberman,Todd J. Sheldon +7 more
TL;DR: In this crossover comparison between HBP and BiVP, HBP was found to effect an equivalent CRT response, suggesting this approach may be feasible in more patients with left bundle branch block than previously assumed.