Journal ArticleDOI
Phosphorus dendrimers for nanomedicine
TLDR
The most salient examples of phosphorus dendrimers used for the elaboration of bio-chips and of supports for cell cultures, for imaging biological events, and for carrying and delivering drugs or biomacromolecules are presented in this paper.About:
This article is published in Chemical Communications.The article was published on 2017-08-31. It has received 62 citations till now. The article focuses on the topics: Nanomedicine.read more
Citations
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Smart nanocarrier-based drug delivery systems for cancer therapy and toxicity studies: A review
Sarwar Hossen,M. Khalid Hossain,Mohammad Khairul Basher,M.N.H. Mia,Moizur Rahman,M. Jalal Uddin +5 more
TL;DR: In this paper, the authors highlight the recent development of smart drug delivery systems for a number of smart nanocarriers, including liposomes, micelles, dendrimers, meso-porous silica nanoparticles, gold nanoparticles and carbon nanotubes.
Journal ArticleDOI
Liposomes: Clinical Applications and Potential for Image-Guided Drug Delivery.
Narottam Lamichhane,Thirupandiyur S. Udayakumar,Warren D. D'Souza,Charles B. Simone,Srinivasa R. Raghavan,Jerimy C. Polf,Javed Mahmood +6 more
TL;DR: Clinical applications of liposomal formulation and their potential imaging properties are reviewed, to enhance therapeutic effectiveness of new and established drugs that are in preclinical and clinical trials.
Journal ArticleDOI
Dendrimers in combination with natural products and analogues as anti-cancer agents
Serge Mignani,João Rodrigues,João Rodrigues,Helena Tomás,Maria Zablocka,Xiangyang Shi,Xiangyang Shi,Anne-Marie Caminade,Anne-Marie Caminade,Jean-Pierre Majoral,Jean-Pierre Majoral +10 more
TL;DR: The most significant advantages of using dendrimers in nanomedicine are their high biocompatibility, good water solubility, and their entry through an endocytosis process.
Journal ArticleDOI
Dendrimers in the context of nanomedicine.
Ana Paula Vieira Dias,Soraya da Silva Santos,Joao Vitor Da Silva,Roberto Parise-Filho,Elizabeth Igne Ferreira,Omar A. El Seoud,Jeanine Giarolla +6 more
TL;DR: This review focused in providing examples of dendrimers used in nanomedicine, with a total of six derivatives in clinical trials and seven products available in the market.
Journal ArticleDOI
Nanosystems as Vehicles for the Delivery of Antimicrobial Peptides (AMPs)
TL;DR: The use of vehicles for the delivery of AMP, such as polymers, nanoparticles, micelles, carbon nanotubes, dendrimers, and other types of systems, allows the use of AMPs as a real alternative to treatment with antibiotics.
References
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Journal ArticleDOI
Two-Photon Laser Scanning Fluorescence Microscopy
TL;DR: The fluorescence emission increased quadratically with the excitation intensity so that fluorescence and photo-bleaching were confined to the vicinity of the focal plane as expected for cooperative two-photon excitation.
Journal ArticleDOI
A new class of polymers: Starburst-dendritic macromolecules
Donald A. Tomalia,H. Baker,James R Dewald,Michael B. Hall,G. Kallos,Steven J. Martin,J. Roeck,J. Ryder,Patrick B. Smith +8 more
TL;DR: Starburst polymers as mentioned in this paper are a class of topological macromolecules which are derived from classical monomers/oligomers by their extraordinary symmetry, high branching and maximized terminal functionality density.
Journal ArticleDOI
The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles.
TL;DR: Findings on the role of surface charge on cytotoxicity in general, action on specific cellular targets, modes of toxic action, cellular uptake, and intracellular localization of NPs are summarized.
Journal ArticleDOI
Polyamidoamine cascade polymers mediate efficient transfection of cells in culture
Jean Haensler,Francis C. Szoka +1 more
TL;DR: It is shown, using luciferase and beta-galactosidase containing plasmids, that dendrimers mediate high efficiency transfection of a variety of suspension and adherent cultured mammalian cells.
Journal ArticleDOI
Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers
Jolanta F. Kukowska-Latallo,Anna U. Bielinska,Jennifer Johnson,Ralph Spindler,Donald A. Tomalia,James R. Baker +5 more
TL;DR: It is demonstrated that Starburst dendrimers can transfect a wide variety of cell types in vitro and offer an efficient method for producing permanently transfected cell lines.
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The key role of the scaffold on the efficiency of dendrimer nanodrugs
Anne-Marie Caminade,Anne-Marie Caminade,Séverine Fruchon,Séverine Fruchon,Cédric-Olivier Turrin,Cédric-Olivier Turrin,Mary Poupot,Mary Poupot,Armelle Ouali,Armelle Ouali,Alexandrine Maraval,Alexandrine Maraval,Matteo Garzoni,Marek Maly,Victor Furer,Valeri I. Kovalenko,Jean-Pierre Majoral,Jean-Pierre Majoral,Giovanni M. Pavan,Rémy Poupot,Rémy Poupot +20 more