Plant terpenes: defense responses, phylogenetic analysis, regulation and clinical applications
Bharat Singh,R. A. Sharma +1 more
- Vol. 5, Iss: 2, pp 129-151
TLDR
In this review paper, recent developments in the biosynthesis of terpenoids, indepth description of terpene synthases and their phylogenetic analysis, regulation of ter pene biosynthesis as well as updates of ter penes which have entered in the clinical studies are reviewed thoroughly.Abstract:
The terpenoids constitute the largest class of natural products and many interesting products are extensively applied in the industrial sector as flavors, fragrances, spices and are also used in perfumery and cosmetics. Many terpenoids have biological activities and also used for medical purposes. In higher plants, the conventional acetate-mevalonic acid pathway operates mainly in the cytosol and mitochondria and synthesizes sterols, sesquiterpenes and ubiquinones mainly. In the plastid, the non-mevalonic acid pathway takes place and synthesizes hemi-, mono-, sesqui-, and diterpenes along with carotenoids and phytol tail of chlorophyll. In this review paper, recent developments in the biosynthesis of terpenoids, indepth description of terpene synthases and their phylogenetic analysis, regulation of terpene biosynthesis as well as updates of terpenes which have entered in the clinical studies are reviewed thoroughly.read more
Citations
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Cannabis sativa: The Plant of the Thousand and One Molecules
TL;DR: Prospects on the benefits linked to the use of the -omics technologies, such as metabolomics and transcriptomics to speed up the identification and the large-scale production of lead agents from bioengineered Cannabis cell culture, are presented.
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Uncovering Potential Applications of Cyanobacteria and Algal Metabolites in Biology, Agriculture and Medicine: Current Status and Future Prospects
Rachana Singh,Parul Parihar,Madhulika Singh,Andrzej Bajguz,Jitendra Kumar,Samiksha Singh,Vijay Pratap Singh,Sheo Mohan Prasad +7 more
TL;DR: In this review, an endeavor has been made to uncover the significance of various metabolites like phenolics, phytoene/terpenoids, phytols, sterols, free fatty acids, photoprotective compounds, etc., which have several biotechnological, industrial, pharmaceutical, and cosmetic uses.
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Volatile terpenoids: multiple functions, biosynthesis, modulation and manipulation by genetic engineering
Farhat Abbas,Yanguo Ke,Rangcai Yu,Yuechong Yue,Sikandar Amanullah,Muhammad Muzammil Jahangir,Yanping Fan +6 more
TL;DR: This review summarizes the recent advances in biosynthetic pathways, including the spatiotemporal, transcriptional and post-transcriptional regulatory mechanisms, and discusses the multiple functions of the terpene synthase genes (TPS), their interaction with the surrounding environment and the use of genetic engineering for terpenoid production in model plants.
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Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science
TL;DR: Knowledge of the individual medicinal properties of the cannabinoids, terpenes, and flavonoids is necessary to cross‐breed strains to obtain optimal standardized synergistic compositions, which will enable targeting individual symptoms and/or diseases.
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The molecular biology of fruity and floral aromas in beer and other alcoholic beverages.
Sylvester Holt,Marta H. Mikš,Bruna Trindade de Carvalho,Maria R. Foulquié-Moreno,Johan M. Thevelein +4 more
TL;DR: The molecular biology of a major subset of beer aroma volatiles, fruity and floral compounds, originating from raw materials, or formed by yeast during fermentation, is discussed.
References
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