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Porous titanium materials with entangled wire structure for load-bearing biomedical applications.

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TLDR
This kind of porous metal-entangled titanium wire material is very promising for implant applications because of their very good toughness, perfect flexibility, high strength, adequate elastic modulus, and low cost.
Abstract
A kind of porous metal-entangled titanium wire material has been investigated in terms of the pore structure (size and distribution), the strength, the elastic modulus, and the mechanical behavior under uniaxial tensile loading. Its functions and potentials for surgical application have been explained. In particular, its advantages over competitors (e.g., conventional porous titanium) have been reviewed. In the study, a group of entangled titanium wire materials with non-woven structure were fabricated by using 12–180 MPa forming pressure, which have porosity in a range of 48%–82%. The pores in the materials are irregular in shape, which have a nearly half-normal distribution in size range. The yield strength, ultimate tensile strength, and elastic modulus are 75 MPa, 108 MPa, and 1.05 GPa, respectively, when its porosity is 44.7%. The mechanical properties decrease significantly as the porosity increases. When the porosity is 57.9%, these values become 24 MPa, 47.5 MPa, and 0.33 GPa, respectively. The low elastic modulus is due to the structural flexibility of the entangled titanium wire materials. For practical reference, a group of detailed data of the porous structure and the mechanical properties are reported. This kind of material is very promising for implant applications because of their very good toughness, perfect flexibility, high strength, adequate elastic modulus, and low cost.

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TL;DR: An overview of the design of ideal biomimetic porous scaffolds for bone tissue engineering is presented, and concepts and techniques including the production of a hierarchical structure on both the macro- and nano-scales, the adjustment of biomechanical properties through structural alignment and chemical components, and the control of the biodegradability of the scaffold and its by-products are discussed.
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New Developments of Ti-Based Alloys for Biomedical Applications

TL;DR: Efforts have been made to reveal the latest scenario of bulk and porous Ti-based materials for biomedical applications, emphasizing their current status, future opportunities and obstacles for expanded applications.
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Bone tissue engineering via growth factor delivery: from scaffolds to complex matrices

TL;DR: An analysis of scaffold-based growth factor delivery strategies found in the recent literature shows great promise, both by providing sustained release over a therapeutically relevant timeframe and the potential to sequentially deliver multiple growth factors.
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New Ti-Alloys and Surface Modifications to Improve the Mechanical Properties and the Biological Response to Orthopedic and Dental Implants: A Review.

TL;DR: The aim of this paper is to discuss the current trends, advantages, and disadvantages of new titanium-based biomaterials, fabricated to enhance the quality of life of many patients around the world.
Journal ArticleDOI

Fabrication, pore structure and compressive behavior of anisotropic porous titanium for human trabecular bone implant applications.

TL;DR: Porous titanium with 60-70% porosity has potential for trabecular bone implant applications and relationship between compressive properties and porosity conforms well to the Gibson-Ashby model.
References
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Book

Cellular Solids: Structure and Properties

TL;DR: The linear elasticity of anisotropic cellular solids is studied in this article. But the authors focus on the design of sandwich panels with foam cores and do not consider the properties of the materials.
Journal ArticleDOI

A variational approach to the theory of the elastic behaviour of multiphase materials

TL;DR: In this paper, the authors derived upper and lower bounds for the effective elastic moduli of quasi-isotropic and quasi-homogeneous multiphase materials of arbitrary phase geometry.
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Ti based biomaterials, the ultimate choice for orthopaedic implants – A review

TL;DR: In this paper, the influence of alloy chemistry, thermomechanical processing and surface condition on these properties is discussed and various surface modification techniques to achieve superior biocompatibility, higher wear and corrosion resistance.
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Porous scaffold design for tissue engineering

TL;DR: The integration of CTD with SFF to build designer tissue-engineering scaffolds is reviewed and the mechanical properties and tissue regeneration achieved using designer scaffolds are details.
Journal ArticleDOI

Manufacture, characterisation and application of cellular metals and metal foams

TL;DR: The possibilities for manufacturing metal foams or other porous metallic structures are reviewed in this article, where various manufacturing processes are classified according to the state of matter in which the metal is processed, such as solid, liquid, gaseous or ionised.
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