Ralstonia mannitolilytica in cystic fibrosis: A new predictor of worse outcomes
I. Coman,L. Bilodeau,Annick Lavoie,Maite Carricart,François Tremblay,J.E. Zlosnik,Yves Berthiaume +6 more
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TLDR
New pathogens are identified with the evolution of the microbiota in cystic fibrosis respiratory tracts, and acquisition of Ralstonia spp.Abstract:
Background
Patients with Cystic Fibrosis are subject to repeated respiratory tract infections, with recent increasing isolation of unusual pathogens. Ralstonia species have lately been isolated at our institution, an organism historically frequently misidentified as Burkholderia or Pseudomonas. The prevalence of Ralstonia spp. in cystic fibrosis populations has yet to be determined, along with its clinical implications.read more
Citations
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The role of multispecies social interactions in shaping Pseudomonas aeruginosa pathogenicity in the cystic fibrosis lung.
TL;DR: This work discusses how P. aeruginosa-secreted products can have community-wide effects, with the potential to ultimately shape microbial community dynamics within the lung, and focuses on three well-studied traits associated with worsening clinical outcome in CF: phenazines, siderophores and biofilm formation.
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Phylogenetic Analysis and Antimicrobial Profiles of Cultured Emerging Opportunistic Pathogens (Phyla Actinobacteria and Proteobacteria) Identified in Hot Springs.
Jocelyn Leonie Jardine,Akebe Luther King Abia,Vuyo Mavumengwana,Eunice Ubomba-Jaswa,Eunice Ubomba-Jaswa +4 more
TL;DR: It is suggested that hot springs are potential reservoirs for emerging opportunistic pathogens, including multiple antibiotic resistant strains, and highlights the presence of unknown populations of emerging and potential waterborne opportunism pathogens in the environment.
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Betaproteobacteria are predominant in drinking water: are there reasons for concern?
TL;DR: It is demonstrated that DW holds a high diversity of Betaproteobacteria, whose presence may not be innocuous, and is placed in the list of candidates of emerging opportunistic pathogens.
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Culture-independent Characterization of the Microbiome of Healthy Pulp.
Christopher Widmer,Jorie Skutas,Cole G. Easson,Jose V. Lopez,Calvin Torneck,Michael Flax,Taner Cem Sayin +6 more
TL;DR: Evidence is presented that the pulp spaces of pristine healthy teeth contain detectable bacterial DNA, supporting the long‐held hypothesis that healthy pulp lack bacteria.
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Coinfection with Pseudomonas aeruginosa and Aspergillus fumigatus in cystic fibrosis
TL;DR: A complex relationship exists between P. aeruginosa and A. fumigatus and is associated with worsened clinical disease in cystic fibrosis, and robust longitudinal studies are required to derive causality and to determine whether interspecies interaction contributes to disease progression.
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