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Open AccessJournal ArticleDOI

Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries

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- 01 Jan 2022 - 
- Vol. 7, pp 47-72
TLDR
In this article , the authors summarized the applications of reactive oxygen species (ROS)-based nanoparticles, highlighting the latest achievements of nanotechnology researches for the treatment of myocardial ischemia reperfusion injury.
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This article is published in Bioactive Materials.The article was published on 2022-01-01 and is currently open access. It has received 97 citations till now. The article focuses on the topics: Reperfusion injury & Myocardial infarction.

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Rheumatoid arthritis microenvironment insights into treatment effect of nanomaterials

TL;DR: Wang et al. as discussed by the authors systematically introduced the unique features, constitutes of the RAM, and emphasized the key role of the vicious circle of reactive oxygen and nitrogen species (RONS) and inflammatory factors in the RA progress.
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Reactive Oxygen Species Scavenging Nanomedicine for the Treatment of Ischemic Heart Disease

TL;DR: The roles of ROS in both IHD and its risk factors are discussed, highlighting cardiovascular medications that have antioxidant properties and summarizing the advantages, properties, and recent achievements of nanomedicines that have ROS scavenging capacity for the treatment of diabetes, hypertension, hypercholesterolemia, atherosclerosis, ischemia/reperfusion, and myocardial infarction.
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Harnessing reactive oxygen/nitrogen species and inflammation: Nanodrugs for liver injury

TL;DR: In this article , a review of the latest developments contributing to our understanding of the mechanisms underlying nanodrugs in the treatment of liver injury via harnessing reactive oxygen/nitrogen species (RONS) and inflammation plays a key role in progression of liver disease.
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Passively-targeted mitochondrial tungsten-based nanodots for efficient acute kidney injury treatment

- 01 Mar 2023 - 
TL;DR: In this paper , an ultra-small Tungsten-based nanodots (TWNDs) with strong ROS scavenging can be very effective for treatment of acute kidney injury (AKI).
Journal ArticleDOI

Nanodrugs alleviate acute kidney injury: Manipulate RONS at kidney

TL;DR: In this article , the authors summarized the emerging nanodrugs that exploit the pathological and physiological features of the kidney to overcome the limitations of traditional small-molecule drugs to achieve high AKI efficacy.
References
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MicroRNAs: Target Recognition and Regulatory Functions

TL;DR: The current understanding of miRNA target recognition in animals is outlined and the widespread impact of miRNAs on both the expression and evolution of protein-coding genes is discussed.
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Free radicals and antioxidants in normal physiological functions and human disease

TL;DR: Attention is focussed on the ROS/RNS-linked pathogenesis of cancer, cardiovascular disease, atherosclerosis, hypertension, ischemia/reperfusion injury, diabetes mellitus, neurodegenerative diseases, rheumatoid arthritis, and ageing.
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The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology

TL;DR: This review summarizes the current state of knowledge of the functions of NOX enzymes in physiology and pathology.
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Intrinsic peroxidase-like activity of ferromagnetic nanoparticles

TL;DR: It is reported that magnetite nanoparticles in fact possess an intrinsic enzyme mimetic activity similar to that found in natural peroxidases, which are widely used to oxidize organic substrates in the treatment of wastewater or as detection tools.
Journal ArticleDOI

ROS Function in Redox Signaling and Oxidative Stress

TL;DR: It is argued that redox biology, rather than oxidative stress, underlies physiological and pathological conditions.
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