Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries
TLDR
In this article , the authors summarized the applications of reactive oxygen species (ROS)-based nanoparticles, highlighting the latest achievements of nanotechnology researches for the treatment of myocardial ischemia reperfusion injury.About:
This article is published in Bioactive Materials.The article was published on 2022-01-01 and is currently open access. It has received 97 citations till now. The article focuses on the topics: Reperfusion injury & Myocardial infarction.read more
Citations
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Rheumatoid arthritis microenvironment insights into treatment effect of nanomaterials
Yan Zhu,Tianjiao Zhao,Min Liu,Shuya Wang,Saili Liu,Yunchen Yang,Yuqiong Yang,Yayun Nan,Qiong Huang,Kelong Ai +9 more
TL;DR: Wang et al. as discussed by the authors systematically introduced the unique features, constitutes of the RAM, and emphasized the key role of the vicious circle of reactive oxygen and nitrogen species (RONS) and inflammatory factors in the RA progress.
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Reactive Oxygen Species Scavenging Nanomedicine for the Treatment of Ischemic Heart Disease
Zhan Zhang,Rinkoo Dalan,Zhenyu Hu,Jiong-Wei Wang,Nicholas Chew,Kian Keong Poh,Ru San Tan,Tuck Wah Soong,Yu-ping Dai,Lei Ye,Xiaoyuan Chen +10 more
TL;DR: The roles of ROS in both IHD and its risk factors are discussed, highlighting cardiovascular medications that have antioxidant properties and summarizing the advantages, properties, and recent achievements of nanomedicines that have ROS scavenging capacity for the treatment of diabetes, hypertension, hypercholesterolemia, atherosclerosis, ischemia/reperfusion, and myocardial infarction.
Journal ArticleDOI
Harnessing reactive oxygen/nitrogen species and inflammation: Nanodrugs for liver injury
TL;DR: In this article , a review of the latest developments contributing to our understanding of the mechanisms underlying nanodrugs in the treatment of liver injury via harnessing reactive oxygen/nitrogen species (RONS) and inflammation plays a key role in progression of liver disease.
Journal ArticleDOI
Passively-targeted mitochondrial tungsten-based nanodots for efficient acute kidney injury treatment
TL;DR: In this paper , an ultra-small Tungsten-based nanodots (TWNDs) with strong ROS scavenging can be very effective for treatment of acute kidney injury (AKI).
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Nanodrugs alleviate acute kidney injury: Manipulate RONS at kidney
Qiaohui Chen,Yayun Nan,Yuqi Yang,Zuoxiu Xiao,Min Liu,Jia Huang,Yu Xiang,Xingyu Long,Tianjiao Zhao,Xin Wang,Qiong Huang,Kelong Ai +11 more
TL;DR: In this article , the authors summarized the emerging nanodrugs that exploit the pathological and physiological features of the kidney to overcome the limitations of traditional small-molecule drugs to achieve high AKI efficacy.
References
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Journal ArticleDOI
MicroRNAs: Target Recognition and Regulatory Functions
TL;DR: The current understanding of miRNA target recognition in animals is outlined and the widespread impact of miRNAs on both the expression and evolution of protein-coding genes is discussed.
Journal ArticleDOI
Free radicals and antioxidants in normal physiological functions and human disease
TL;DR: Attention is focussed on the ROS/RNS-linked pathogenesis of cancer, cardiovascular disease, atherosclerosis, hypertension, ischemia/reperfusion injury, diabetes mellitus, neurodegenerative diseases, rheumatoid arthritis, and ageing.
Journal ArticleDOI
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
Karen Bedard,Karl-Heinz Krause +1 more
TL;DR: This review summarizes the current state of knowledge of the functions of NOX enzymes in physiology and pathology.
Journal ArticleDOI
Intrinsic peroxidase-like activity of ferromagnetic nanoparticles
Lizeng Gao,Jie Zhuang,Leng Nie,Jinbin Zhang,Yu Zhang,Ning Gu,Taihong Wang,Jing Feng,Dongling Yang,Sarah Perrett,Xiyun Yan +10 more
TL;DR: It is reported that magnetite nanoparticles in fact possess an intrinsic enzyme mimetic activity similar to that found in natural peroxidases, which are widely used to oxidize organic substrates in the treatment of wastewater or as detection tools.
Journal ArticleDOI
ROS Function in Redox Signaling and Oxidative Stress
TL;DR: It is argued that redox biology, rather than oxidative stress, underlies physiological and pathological conditions.