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Relationship between sarcopenia and physical activity in older people: a systematic review and meta-analysis.

TLDR
A systematic review and meta-analysis of cross-sectional and cohort studies exploring the relationship between PA and sarcopenia in older people confirmed the beneficial influence of PA in general for the prevention of sarc Openia.
Abstract
Physical activity (PA) has been identified as beneficial for many diseases and health disorders, including sarcopenia The positive influence of PA interventions on sarcopenia has been described previously on many occasions Current reviews on the topic include studies with varied PA interventions for sarcopenia; nevertheless, no systematic review exploring the effects of PA in general on sarcopenia has been published The main aim of this study was to explore the relationship between PA and sarcopenia in older people on the basis of cross-sectional and cohort studies We searched PubMed, Scopus, EBSCOhost, and ScienceDirect for articles addressing the relationship between PA and sarcopenia Twenty-five articles were ultimately included in the qualitative and quantitative syntheses A statistically significant association between PA and sarcopenia was documented in most of the studies, as well as the protective role of PA against sarcopenia development Furthermore, the meta-analysis indicated that PA reduces the odds of acquiring sarcopenia in later life (odds ratio [OR] =045; 95% confidence interval [CI] 037-055) The results of this systematic review and meta-analysis confirm the beneficial influence of PA in general for the prevention of sarcopenia

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Sarcopenia and type 2 diabetes mellitus: a bidirectional relationship.

TL;DR: The current literature highlighting the bidirectional relationship between T2DM and sarcopenia is discussed, current research gaps and treatments are highlighted, and recommendations for future research are provided.
Journal ArticleDOI

Vitamin D Deficiency and Sarcopenia in Older Persons.

TL;DR: The biological, clinical and epidemiological evidence supporting the hypothesis of a causal association between Vitamin D deficiency and an increased risk of sarcopenia in older people is summarized.
Journal ArticleDOI

Osteoporosis and Sarcopenia Increase Frailty Syndrome in the Elderly.

TL;DR: The aim of this review is to analyze the pathophysiological mechanisms underlying the frailty syndrome and its association with sarcopenia and osteoporosis, and investigate possible intervention measures.
References
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Journal ArticleDOI

Measuring inconsistency in meta-analyses

TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
Journal ArticleDOI

Bias in meta-analysis detected by a simple, graphical test

TL;DR: Funnel plots, plots of the trials' effect estimates against sample size, are skewed and asymmetrical in the presence of publication bias and other biases Funnel plot asymmetry, measured by regression analysis, predicts discordance of results when meta-analyses are compared with single large trials.

The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Nonrandomised Studies in Meta-Analyses

TL;DR: The Newcastle-Ottawa Scale (NOS) as discussed by the authors was developed to assess the quality of nonrandomised studies with its design, content and ease of use directed to the task of incorporating the quality assessments in the interpretation of meta-analytic results.
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