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Restless legs syndrome in 218 patients: associated disorders.

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TLDR
RLS patients are much more likely to have previously been diagnosed with extrapyramidal disorders, musculoskeletal disorders, depression, and painful conditions such as joint and back disorders.
About
This article is published in Sleep Medicine.The article was published on 2000-07-01. It has received 131 citations till now. The article focuses on the topics: Extrapyramidal disorder & Polysomnography.

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Citations
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Journal ArticleDOI

Prevalence of restless legs syndrome and periodic limb movement disorder in the general population.

TL;DR: PLMD and RLS are prevalent in the general population and both conditions are associated with several physical and mental disorders and may negatively impact sleep.
Journal ArticleDOI

Restless legs syndrome: a review of clinical and pathophysiologic features.

TL;DR: This review of RLS covers history, diagnosis, morbidity of sleep disturbance, relation to periodic limb movements in both sleep and waking, secondary causes, severity assessment methods, phenotypes for possible genetic patterns, epidemiology, pathophysiology, and medical treatmentconsiderations.
Journal ArticleDOI

Dopamine and iron in the pathophysiology of restless legs syndrome (RLS).

TL;DR: It is concluded that there may be an iron-dopamine connection central to the pathophysiology of RLS for at least some if not most patients with this disorder.
References
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Journal ArticleDOI

The International Classification of Sleep Disorders: Diagnostic and Coding Manual

Robert B. Daroff
- 01 Jan 1991 - 
TL;DR: This outstanding manual is more than an outline; it includes diagnostic criteria, clinical course, predisposing factors, prevalence, differential diagnosis, and a bibliography for each of the numerous disorders.
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Epidemiologic study of sleep disturbances and psychiatric disorders : an opportunity for prevention

TL;DR: As part of the National Institute of Mental Health Epidemiologic Catchment Area study, 7954 respondents were questioned at baseline and 1 year later about sleep complaints and psychiatric symptoms using the Diagnostic Interview Schedule.
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Sleep disturbance and psychiatric disorders: A longitudinal epidemiological study of young Adults

TL;DR: Prior insomnia remained a significant predictor of subsequent major depression when history of other prior depressive symptoms was controlled for, and complaints of 2 weeks or more of insomnia nearly every night might be a useful marker of subsequent onset of major depression.
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Toward a better definition of the restless legs syndrome

TL;DR: A large International Restless Legs Syndrome (RLS) Study Group has been formed as discussed by the authors, which has taken upon itself the role of definig the clinical features of the RLS, including sleep disturbance, periodic limb movements in sleep and similar involuntary movements while awake, a normal neurological examination in the idiopathic from, a tendency for the symptoms to be worse in middle to older age, and a family history suggestive of an autosomal dominant mode of inheritance.
Journal ArticleDOI

Restless legs syndrome

Karl Ekbom
- 01 Sep 1960 - 
TL;DR: Restless legs syndrome is a common cause of insomnia related to problems with sleep initiation and sleep maintenance, unrefreshing sleep, and excessive daytime sleepiness, and it may signify an underlying medical condition as mentioned in this paper.
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